26 research outputs found

    Kerr-Schild spacetimes with (A)dS background

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    General properties of Kerr-Schild spacetimes with (A)dS background in arbitrary dimension are studied. It is shown that the geodetic Kerr-Schild vector k is a multiple WAND of the spacetime. Einstein Kerr-Schild spacetimes with non-expanding k are shown to be of Weyl type N, while the expanding spacetimes are of type II or D. It is shown that this class of spacetimes obeys the optical constraint. This allows us to solve Sachs equation, determine r-dependence of boost weight zero components of the Weyl tensor and discuss curvature singularities.Comment: 17 pages, minor change

    Spatio-temporal Models of Lymphangiogenesis in Wound Healing

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    Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries. Although many mathematical models have been developed to describe the formation of blood capillaries (angiogenesis), very few have been proposed for the regeneration of the lymphatic network. Lymphangiogenesis is a markedly different process from angiogenesis, occurring at different times and in response to different chemical stimuli. Two main hypotheses have been proposed: 1) lymphatic capillaries sprout from existing interrupted ones at the edge of the wound in analogy to the blood angiogenesis case; 2) lymphatic endothelial cells first pool in the wound region following the lymph flow and then, once sufficiently populated, start to form a network. Here we present two PDE models describing lymphangiogenesis according to these two different hypotheses. Further, we include the effect of advection due to interstitial flow and lymph flow coming from open capillaries. The variables represent different cell densities and growth factor concentrations, and where possible the parameters are estimated from biological data. The models are then solved numerically and the results are compared with the available biological literature.Comment: 29 pages, 9 Figures, 6 Tables (39 figure files in total

    Adaptation of the Amsterdam Inventory for Auditory Disability and Handicap into Cantonese

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    This research aimed to adapt the Amsterdam Inventory for Auditory Disability and Handicap (AIADH) into Cantonese. A total of six Cantonese-English bilingual speakers participated in the adaptation of the AIADH. One-hundred and thirty- three normal-hearing and hearing-impaired Chinese-speaking participants from Hong Kong completed the Cantonese adaptation of the questionnaire (C-AIADH). Good internal consistency and reliability of the questionnaire was indicated by a high Cronbach's alpha coefficient. Statistical analysis showed that the newly adapted questionnaire could differentiate between normal-hearing and hearing-impaired subjects. Percentiles were computed from the data obtained from normal-hearing subjects (n = 35) to obtain normal scores for the C-AIADH. The findings and possible clinical uses are discussed
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