A Combinatorial Discussion on Finite Dimensional Leavitt Path Algebras

Any finite dimensional semisimple algebra A over a field K is isomorphic to a direct sum of finite dimensional full matrix rings over suitable division rings. In this paper we will consider the special case where all division rings are exactly the field K. All such finite dimensional semisimple algebras arise as a finite dimensional Leavitt path algebra. For this specific finite dimensional semisimple algebra A over a field K, we define a uniquely detemined specific graph - which we name as a truncated tree associated with A - whose Leavitt path algebra is isomorphic to A. We define an algebraic invariant {\kappa}(A) for A and count the number of isomorphism classes of Leavitt path algebras with {\kappa}(A)=n. Moreover, we find the maximum and the minimum K-dimensions of the Leavitt path algebras of possible trees with a given number of vertices and determine the number of distinct Leavitt path algebras of a line graph with a given number of vertices.Comment: 10 pages, 5 figure

Colorectal Cancer Prevention and Risk Counseling

Colorectal cancer (CRC) is one of the leading causes of cancer death in the world. Many risk factors have been identified in the development of colorectal cancer. It is necessary to carry out activities related to risk factors in order to implement effective CRC early diagnosis and screening programs and achieve positive outcomes. International screening guidelines have been created and these are being implemented by individual countries according to their own health policies. Colorectal cancer prevention and early training in terms of disease identification, counseling against negative disease perceptions, and changing false beliefs will reduce the fear of CRC and ensure the development of positive health behaviors and acceptance of screening. Among recent developments in cancer prevention, “cancer risk counseling” has become quite prominent. Individual-specific colorectal cancer risk counseling programs are developed through the assessment of individual risk factors by focusing on a genetic assessment and the development of a risk management plan. This chapter will examine and define colorectal cancer prevention and risk counseling strategies in relation with the relative literature

A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia

The objective was to apply a population model to describe the time course and variability of serum creatinine (sCr) in (near)term neonates with moderate to severe encephalopathy during and after therapeutic hypothermia (TH). The data consisted of sCr observations up to 10 days of postnatal age in neonates who underwent TH during the first 3 days after birth. Available covariates were birth weight (BWT), gestational age (GA), survival, and acute kidney injury (AKI). A previously published population model of sCr kinetics in neonates served as the base model. This model predicted not only sCr but also the glomerular filtration rate normalized by its value at birth (GFR/GFR0). The model was used to compare the TH neonates with a reference full term non-asphyxiated population of neonates. The estimates of the model parameters had good precision and showed high between subject variability. AKI influenced most of the estimated parameters denoting a strong impact on sCr kinetics and GFR. BWT and GA were not significant covariates. TH transiently increased sCr in TH neonates over the first days compared to the reference group. Asphyxia impacted not only GFR, but also the sCr synthesis rate. We also observed that AKI neonates exhibit a delayed onset of postnatal GFR increase and have a higher sCr synthesis rate compared to no-AKI patients. Our findings show that the use of sCr as marker of renal function in asphyxiated neonates treated with TH to guide dose selection for renally cleared drugs is challenging, while we captured the postnatal sCr patterns in this specific population. Graphical Abstract: [Figure not available: see fulltext.].</p

Retinopathy of prematurity (ROP): From the perspective of the neonatologist

Retinopathy of prematurity (ROP) is a serious morbidity of prematurity. It is a pathophysiological condition that occurs due to abnormal proliferation of the retinal vessels. The incidence and severity of ROP increase with decreasing gestational age (GA) and birth weight (BW).The enhanced chance of survival of premature babies in parallel with the developments in neonatal care increased the incidence of ROP. Early diagnosis and timely and appropriate treatment of ROP increases the quality of life by preventing vision loss.Many risk factors were reported besides prematurity and inappropriate oxygen treatment for preterm infants. Pediatricians and neonatologists play important role in prevention, detection and management of ROP. It should be kept in mind that ROP may also lead to medicolegal problems

The Effects of Surfactant on Oxygenation in Term Infants with Respiratory Failure

Objective: The objective of the study was to evaluate the effects of exogenous surfactant on respiratory indices in term infants with respiratory failure. Methods: Consecutive 18 mechanically ventilated term infants, who received a single dose of exogenous surfactant were retrospectively included into the study. The respiratory outcome of surfactant rescue therapy was evaluated by comparing respiratory indices before and six hours after surfactant administration. Findings: Median oxygenation index (OI), mean alveolar pressure (MAP) and fraction of inspired oxygen (FiO2) values were significantly decreased (P<0.001); median arterial oxygen partial pressure (PaO2), arterial oxygen saturation (SaO2) and PaO2/FiO2 values were significantly increased six hours after surfactant treatment (P<0.001). Conclusion: Rescue therapy with surfactant was found to be effective in the improvement of early respiratory indices in term infants with respiratory failure