Urticaria and infections

Urticaria is a group of diseases that share a distinct skin reaction pattern. Triggering of urticaria by infections has been discussed for many years but the exact role and pathogenesis of mast cell activation by infectious processes is unclear. In spontaneous acute urticaria there is no doubt for a causal relationship to infections and all chronic urticaria must have started as acute. Whereas in physical or distinct urticaria subtypes the evidence for infections is sparse, remission of annoying spontaneous chronic urticaria has been reported after successful treatment of persistent infections. Current summarizing available studies that evaluated the course of the chronic urticaria after proven Helicobacter eradication demonstrate a statistically significant benefit compared to untreated patients or Helicobacter-negative controls without urticaria (p < 0.001). Since infections can be easily treated some diagnostic procedures should be included in the routine work-up, especially the search for Helicobacter pylori. This review will update the reader regarding the role of infections in different urticaria subtypes

Literature selections [Literatür Seçmeleri]

Steven Johnson Sendromunu/Toksik Epidermal Nekroliz Tedavisinde Immunglobulin ile Siklosporinin Retrospektif Karşılaştırılması © 2014 Aves Yayincilik. All rights reserved

Neonatal and infant dermatology, 3rd edition

[No abstract available

Imiquimod

Imiquimod is an immune response-modifying agent that demonstrates potent antiviral and antitumour activity. Although it's use has been approved by the FDA (Food and Drug Administration) in the treatment of external genital and perianal warts, actinic keratosis on the face or scalp and superficial basal cell carcinomas, it has recently been tried to treat different types of dermatological diseases including molluscum contagiosum, herpes simplex, melanoma, T-cell lymphoma. Side effects of imiquimod are erythema, itching, burning, crusting, and rarely cytokine-release syndrome, exacerbation of inflammatory skin conditions. In thi review, the structure of imiquimod, mechanism of action and its usage in the treatment of different skin diseases are discussed. © 2007 Bentham Science Publishers Ltd

A case of reversible telogen effluvium caused by a drug [İlaca bagli gelişen bir reversibl effluvium olgusu]

Effluvium, known as diffuse hair loss, is seen as anagen and telogen effluvium. In telogen effluvium, hair follicles pass from anagen phase to telogen phase prematurely. Certain drugs such as anticoagulants, cytostatics, interpherons, retinoids, lithium carbonate, ß- blockers, antimalarials, sexual hormone preparations and angiotensin converting enzyme inhibitors may be cause of effluvium. In this case, we present a 52 years old female patient suffering from diffuse hair loss after using conjugate estrogen plus progesterone preparation for nearly one-month. Etiological investigations revealed no certain pathological results. After cessation of treatment, hair loss diminished and complete hair regrowth was observed during follow up period. In this report, current literatures related to the topic were reviewed and the role of sexual hormone preparations on hair loss was emphasized