122 research outputs found

    Examining the relationship between the talent and the final grades of undergraduate music education students

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    This study aims to examine the relationship between the talent exam grades (2017) of 2 voice, 3 voice, 4 voice hearing, melody repetition, rythym repetition, dictation, solfege and the final exam grades (2018) of first class undergraduate music education students of a University placed in Blacksea reagion. The same questions were directed to the students both in talent exam and the final exam of Musical Hearing, Reading and Writing lesson at the end of the second semester of the first year, and the corelation among two exam scores are examined. The study group of the article consists of 50 students who became successfull in the talent exam of Music Education Department of Fine Arts Branch of Education Faculty in the year 2017, and 44 of 50 successfull students who registered to the faculty as first class students in 2017-2018. The talent exam grades are accessed with the approval of the deanship. The implementation grades are obtained from the final exam of Musical Hearing, Reading and Writing lesson at the end of the second semester of the first year by directing the same questions. The talent exam grades and the implementation grades of study groups are analysed by using analysis programs, and results are compared. As the conclusion of the study, it’s noted that there is a weak relationship between talent exam and implementation exam grades of 2 voice hearing, 3 voice hearing, 4 voice hearing, melody repetition and solfege, and there is almost no relationship between the grades of rythym repetition. The grades of dictation is higher in the implementation exam

    The comparasion of music teacher candidates’ instrument test grades and instrument sight reading grades in talent exam with individual instrument exam grades during four-years education period

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     Every year Music education programs of the education Faculties, select students through out a talent test. This study aims to compare the instrument test grades and instrument sight reading grades at the talent test with individual instrument test grades of the students of Education Faculty Fine Arts Education Branch Music Education department. At the same time, the study aims to compare the instrument test grades and instrument sight reading grades at the talent test with individual instrument test grades of the students at first, second, third and fourth calass according to the high schools that students graduated. This research is important bescause of showing the 4 year progress of the students from the point of individual instrument playing; at the same time it is important for showing the progress of Fine Arts High School graduates and other high school graduates, and the difference between two groups.  In this research relational search method will be used. The sample of the study consists of 176 student who became successfull at the talent exams in 2012, 2013, 2014 ve 2015 and registered to the Education Faculty Fine Arts Education Branch Music Education department of a University located in Black Sea Reagion. The data of the research is obtained by the approval of the deanship of the Faculty. The data will be analysed with a statistical analyse program which is used for the social sciences. As the result of the study the progress and the difference of the instrument playing and instrument sight reading scores will be shown as tables and will be commented

    A synchronous occurrence of urothelial carcinoma with abundant myxoid stroma and inverted papilloma of the urinary bladder

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    Abundant myxoid stroma rarely occurs in urothelial carcinomas, and may cause diagnostic challenges when cells with eosinophilic cytoplasm forming nests and cords in a myxoid background are seen, particularly in the absence of typical carcinomatous appearance. Microscopic examination of transurethral resection specimen of a 71-year-old male patient revealed non-cohesive oval or elongated tumor cells with eosinophilic cytoplasm arranged in cord-like filigree pattern in an abundant myxoid stroma. Immunohisto chemically the tumor was positive for cytokeratin 7, cytokeratin 20, and 34BE12. About 90 to 100% nuclear staining was observed with p63, p53, and Ki-67. A second neoplasm with a flat overlying urothelial epithelium and a complete inverted cellular growth pattern was also noted. The neoplasm exhibited less than 2% and 10% nuclear staining with Ki-67 and p53, respectively. Considering histological, histochemical, and immunohistochemical findings, a diagnosis of synchronous urothelial carcinoma with abundant myxoid stroma and inverted papilloma was made

    A COVID-19-Related Kawasaki Disease: Our First Multi-system Inflammatory Syndrome in Children Case

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    A new type of coronavirus disease-2019 (COVID-19) epidemic, which started in the last months of 2019, has spread rapidly all over the world and caused many deaths, especially in adults. Recently, a syndromic condition caused by the hyperinflammatory response that is thought to be due to this new pandemic coronavirus factor has been identified, especially in the childhood age group. It has been stated that this response is particularly similar to Kawasaki disease and can manifest itself with multiorgan involvement. This new clinical condition was defined as pediatric inflammatory multi-system syndrome temporally associated with severe acute respiratory syndrome-coronavirus 2 or multi-system inflammatory syndrome in children associated with COVID-19. In this case presentation, a nine-year-old male patient was admitted to our emergency department with complaints similar to ones in Kawasaki disease. The patient was followed up in our pediatric intensive care unit due to hypotension and myocarditis, as well as likely macrophage activation syndrome and simultaneous COVID-19 positivity. For Kawasaki disease, intravenous immunoglobulin, acetylsalicylic acid, low molecular weight heparin and methylprednisolone; for myocarditis, enalapril and furosemide; and for COVID-19, favipiravir was administered to the patient. We would like to present our case to exemplify clinicians dealing with pediatric patients and to assist in easier recognition, prevention, diagnosis and treatment of COVID-19 in all children worldwide

    Structural analysis of pectin, polygalacturonic acid and pectinase enzyme lyophilysed

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    Pektik enzimler, yüksek moleküler ağırlıklı pektik asitlerin indirgeyici olmayan uçlarına atak yaparak monogalakturonatları oluşturan enzimlerdir. Bu enzimler Saprofitik fungus, bakteri ve bazı mayalarca oluşturulmaktadırlar. Meyve ve sebze teknolojilerinde kullanılmaktadır. Bu çalışmada pektin, poligalakturonik asit ve liyofilize bakteriyel pektinazın kristal yapıları, taramalı elektron mikroskobunda (SEM) görüntülenmiştir. SEM’deki görüntülerinde homojen kristal yapı görülmektedir. Pektin poligalakturonik asit ve bakteriyel pektinaz, elektron ışınlarını geçirmeyecek kadar kompakt ve sıkı paketlenmiştir. Ayrıca substrat moleküllerinin kristallerinin pektinaz enziminden daha küçük boyutta olduğu tespit edilmiştir. Pektinazın enzimatik aktivitesini Ca++ ve Na+ gibi katyonların sitimüle ettiği bilinmektedir. Çalışmanın ikinci aşamasında pektinaz enziminin kristal yapısında bulunabilecek elementlerin analizi gerçekleştirilmiştir. Anahtar Kelimeler: Pektinaz, taramalı elektron mikroskop (SEM), yapısal analiz, elementer analiz, pektin, poligalakturonik asit.Pectic substances are pectinic acid, pectin, pectic acid and their salts. Pectin is a polysaccaride found in plants like fruits and vegetables etc in high level. Substances which have no methyl group are pectic acid and polygalacturonic acid. Pectic substances are heteropolysaccarides with 30,000-300,000 molecular weight.Pectic enzymes are known as enzyme destroying chain. Pectic enzymes produce monogalacturonates by attaking the nonreducing end of the high molecular weight pectic acids. These are produced by saprophytic fungi, bacteria and some yeasts. They are used in fruit and vegetable technologies. In this research, crystal structures of pectin, polygalacturonic acid and lyophilysed bacterial pectinase samples were studied by scanning elektron microskop. Homogenous crystal structure was observed from the images at SEM. Pectin, polygalacturonic acid and pectinase enzyme was packed so compact and tightly that no transiion of beam was observed. Pectin crystals have bigger size than polygalacturonic acid crystals. The crystals of substrat molecules was determined to be smaller than pectinase enzymes. Ca++ and Na+ cations are known to stimulate enzymatic activity In second step of study, the elements which are thought to be present in the crystal structure of pectinase were analysed. Analysis results showed that Na, Zn and Ca elements were found at concentrations of 60 %, 29.296 % and 6.555 %, respectively.  Keywords: Pectinase, scanning electron microscopy (SEM), structural analysis, elementary analysis, pectin, polygalacturonic acid

    Development of socıal desirability scale: validity and reliability study

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    Bu çalıĢma bireylerin sosyal beğenirlik düzeylerinin belirlenebilmesine yönelik bir ölçeğin geliĢtirilmesini amaçlamaktadır. Katılımcılar yaĢları 17 ile 45 arasında değiĢen (OrtyaĢ=21.33, Ss=2.32) 527’si kadın (%62), 325’i erkek (%38) toplamda 852 öğrenciden oluĢmaktadır. AraĢtırma kapsamında ölçek maddelerinin dil, anlam ve kapsam geçerliği sağlanmıĢ, pilot uygulama ardından formun nihai hali 426 öğrenciye uygulanarak açımlayıcı faktör analizi yapılmıĢtır. Analiz sonucunda elde edilen faktör yapısının toplam varyansın %52.29’unu açıkladığı belirlenmiĢtir. Iki faktörlü ve 15 maddeden oluĢan yapının doğrulayıcı faktör analizi 426 kiĢilik farklı bir örnekleme uygulanmıĢ elde edilen sonuçlar faktörlerin yapısal uyum gösterdiğini ortaya koymuĢtur (χ2 /df= 2.50, GFI= .93, CFI= .92, AGFI= .91, RMSEA= .06). Güvenirlik analizi için Cronbach Alpha Ġç Tutarlılık katsayısından faydalanılmıĢtır. Analizler ölçeğin bütününün ait güvenirlik katsayısının .84, kabul görme alt boyutunun .85 ve dikkat çekme al boyutunun .75 olduğunu göstermektedir. ÇalıĢma sonucunda, ortaya çıkan 15 maddeli ölçeğin bireylerin sosyal beğenirlik düzeylerinin belirlenmesinde kullanılabilecek geçerli ve güvenilir bir ölçme aracı olduğu görülmüĢtür.This study aims to develop a scale to determine the social desirability levels of individuals. Participants consisted of a total of 852 students, ranging in age from 17 to 45 (Mage= 21.33, Sd= 2.32), 527 female (62%), 325 male (38%). Within the scope of the research, the language, meaning and content validity of the scale items were provided. After the pre application, the final form of the scale was applied to 426 students and exploratory factor analysis was conducted. It was determined that the factor structure obtained as a result of the analysis explained 52.29% of the total variance. Confirmatory factor analysis of the structure consisting of two factors and 15 items was applied to a different sample of 426 people, and the results showed that the factors showed structural adjustment (χ2 /df= 2.50, GFI= .93, CFI= .92, AGFI= .91, RMSEA= .06). Cronbach Alpha Internal Consistency coefficient was used for reliability analysis. As a result of the analysis, the reliability coefficient of the whole scale was .84, the acceptance sub-dimension was .85 and the attention-getting dimension was .75. As a result of the study, it was found that the resulting 15-item scale is a valid and reliable measurement tool that can be used to determine the social desirability levels of individual

    The Histomorphogenetic Relationship between Melanocytes and Langerhans Cells in Ovarian Mature Cystic Teratomas

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    Amaç: Biz bu çalışmada; hücre birimleri, organizasyon ve arşitektürel yapılanmalar bakımından orijinaline yakın sayılabilecek genel anlamda bir vücut yapımı gösteren matür kistik teratomlarda epidermisteki melanositler ve Langerhans hücrelerinin varlığı, birbiri ile sayısal ilişkileri ve birlikte bulunmaları halinde embriyolojik kaynakları hakkında fikir yürütebilmeyi amaçladık. Yöntemler: Sağlık Bakanlığı İstanbul Eğitim ve Araştırma Hastanesi Patoloji Bölümü'nde 2006-2009 yılları arasında rapor edilen 45 matür kistik teratom olgusu çalışmaya alındı. İmmünohistokimyasal olarak; melanositler için Human Melanoma Black-45 (HMB-45) ve Melanoma Antigens (Melan-A) recognized by T cells-1), Langerhans hücreleri için Cluster of Differentiation 1a (CD1a) ve Langerin uygulandı. Bulgular: Langerhans hücreleri olguların %100'ünde tespit edilmekle birlikte, melanositler %88,2'sinde mevcuttu. Sonuç: Bizim çalışmamıza göre Langerhans hücrelerinin, melanositlerin köken aldığı bilinen nöral krest dışında bir kaynaktan gelişmiş olabileceği ve bu iki hücre arasında ilişki olamayabileceği sonucuna vardık.Objective: The purpose of this study was to form a view about the existence, numerical relationship and embryological origin of melanocytes and Langerhans cells when they are found together in mature cystic teratomas which have similar cell types and architectural structure to the original vertebrated body. Methods: Forty five mature cystic teratomas cases, diagnosed in the Ministry of Health İstanbul Education and Research Hospital Pathology Department between 2006-2009 were included in the study. Immunohistochemically, Human Melanoma Black-45 (HMB-45) and Melanoma Antigens (Melan-A) recognized by T cells-1) for melanocytes, Cluster of Differentiation 1a (CD1a) and Langerin for Langerhans cells were applied. Results: Although Langerhans cells were detected in 100%, melanocytes were established in 88.2% of cases. Conclusion: According to our study, Langerhans cells could derive from another source except the neural crest where melanocytes evolve and there is no relationship between them

    Evaluation of the Relationship Between the Severity of the Disease, the Neutrophil/Lymphocyte Ratio and CRP in Children with Bronchiolitis

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    Objective:In this study, we aimed to evaluate the relationship among neutrophil-lymphocyte ratio (NLR), C-reactive protein (CRP) and disease severity in 0-2-year-old children diagnosed and hospitalized with bronchiolitis.Method:This retrospective cross-sectional study includes 158 patients aged 0-2 years, who were hospitalized for bronchiolitis between 01.12.2018 and 04.01.2020 in University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital’s Pediatrics Clinic. Patients’ age, gender, laboratory results and disease severity scores were recorded. According to this, disease severity was categorized as mild, moderate and severe.Results:No statistically significant difference was observed among the scores of disease severity, mean age of the groups and gender distribution (p=0.061, p=0.392). However, a statistically significant difference was found between the disease severity score and the neutrophil/lymphocyte (N/L) ratios (p=0.007). The N/L ratio of the “mild” group was seen as statistically significantly lower than that of the “moderate” and “severe” groups (p=0.003, p=0.006). No statistically significant correlation was detected among the disease severity score, mean age of the moderate and severe groups (r=0.081 p=0.311). A statistically significant difference was witnessed between the disease severity score and CRP values (p=0.014). The CRP values of the group with mild disease were realized to be significantly lower than that of the group with moderate severity (p=0.04).Conclusion:An increase in the NLR along with CRP is associated with the clinical severity and is a beneficial parameter that can be used for evaluating the prognosis of 0-2-year-old hospitalized patients with bronchiolitis

    Are Mean Platelet Volume and Neutrophil-to- Lymphocyte Ratio Valuable in The Early Detection of System Involvements in Henoch-Schönlein Purpura?

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    Aim:Henoch-Schönlein purpura (HSP) is the most common type of vasculitis in childhood, and severe complications due to intestinal and renal involvement can be observed. In this study, it was planned to investigate the value of mean platelet volume (MPV) and neutrophil-tolymphocyte ratio (NLR) in early detection of system involvement in HSP.Methods:A total of 119 patients diagnosed with HSP and 75 healthy controls were included in the study. Data on age, gender and physical examination as well as complete blood count, complete urine examination and faecal occult blood test were obtained from the files of the patients.Results:Gastrointestinal system (GIS) involvement was detected in 41 patients (34.45%), renal involvement in 35 patients (29.41%) and arthritis was detected in 21 patients (17.65%). It was determined that the mean hemoglobin (p=0.02) and MPV values (p=0.0001) o were significantly lower and the mean leukocyte (p=0.0001), platelet (p=0.0001), neutrophil (p=0.0001) count and NLR value (p=0.0001) were significantly higher in patients than in controls. No statistically significant difference was observed in the MPV and NLR values between patients with and without GIS involvement, renal involvement and arthritis.Conclusion:It is thought that MPV and NLR cannot be used as laboratory parameters in the early detection of system involvement in HSP

    Are Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio Related with Hepatosteatosis in Obese Children?

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    Objective: Obesity is an important health problem, which affects children and adolescents and is highly prevalent throughout the world. Non-alcoholic fatty liver disease is fattening that occurs due to non-alcohol causes, and it is associated with obesity in most of the cases. We investigated the relation of mean platelet volume (MPV) and neutrophil-to-lymphocyte ratio (NLR) to hepatosteatosis in obese children in our study.Material and Methods: 104 obese children aged between 4-16 years, who were determined to have a body mass index (BMI) of 95th percentile or higher according to age and gender, were examined retrospectively. The genders, ages, and examination findings of the patients were recorded. In obese children, leukocyte, hemoglobin, platelet, mean platelet volume, neutrophil and lymphocyte levels were assessed in the complete blood count performed during the first application. Neutrophil-to-lymphocyte ratio was calculated. Fasting blood glucose (FBG) and fasting insulin, serum aminotransferase values, ultrasonographic results of patients were recorded.Results: Hepatosteatosis was determined in 64 of 104 patients (61.53%) while it was not determined in 40 patients (38.47%). The BMI, fasting insulin, HOMA-IR, ALT levels were higher in obese children with hepatosteatosis than patients without hepatosteatosis. The average MPV of the group with hepatosteatosis was 7.78±1.57, and the average MPV of the group without hepatosteatosis was 7.42±1.43, no statistical difference was observed between the groups (p=0.236). The average NLR was 1.62±1.06 in the group with hepatosteatosis and 1.38±0.59 in the group without hepatosteatosis. There was no statistical difference between the NLR averages of both groups (p=0.200).Conclusion: No relation was determined between MPV and NLR and liver fattening in obese children
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