185 research outputs found

    Measuring the Capital Energy Value in Historic Structures

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    A credible model to account for the overall energy benefits with retention of historic buildings has been needed since preservation became national policy in 1966. The initial need to measure energy capital in buildings arose from the two energy crises in the 1970s, with a second need to address the sustainability goals of the 1990s/2000s. Both responses measure overall energy efficiency of historic buildings by attempting to account for the energy capital. The Advisory Council on Historic Preservation introduced the first model in 1979, focused on measuring embodied energy and it has remained embedded in preservation vocabulary and is a reflexive argument utilized to advocate for the retention of historic structures over new construction. The second model, the life cycle assessment/avoided impacts is a response to the evolving metrics and currency of sustainability. The Preservation Green Lab further matured the capabilities of the life cycle assessment/avoided impacts model in 2012 with their innovative report, The Greenest Building: Quantifying the Environmental Value of Building Reuse. This thesis evaluates the future of the preservation field to communicate with a common currency regarding retention of historic structures

    Faith Experiences Among Doctoral Psychology Students

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    In order to become culturally competent psychologists, doctoral students must undergo their own process of self-reflection, including personal exploration of religious and spiritual issues. This can prove difficult insofar as many doctoral programs in psychology provide relatively little instruction in religious and spiritual issues. Even among those programs that specialize in religion and spirituality, a shifting of personal faith typically occurs over the course of doctoral training. This study is a step toward understanding the faith experiences of students in one explicitly religious doctoral training program. Faith experiences among students in the George Fox University Graduate Department of Clinical Psychology (GDCP) have been studied before, but not since the GDCP implemented spiritual direction as a program requirement. Results indicate that students continue to experience changes in their faith experiences, likely due to many previously hypothesized reasons such as fatigue, eroding of faith, and possible rearranging of faith (Fisk et al., 2013). Students who report a more favorable experience with their spiritual director reported more willingness to collaborate with clergy for client care. This study continues to raise more questions regarding what can be done to better inform, protect, and encourage the spiritual development of students throughout graduate training in professional psychology. Moreover, it brings into light the possibility of better preparing and training graduate students in collaboration with faith professionals to better meet clients’ treatment needs in a holistic way

    Teachers\u27 Knowledge and Misconceptions of Postconcussion Symptoms

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    Concussion, or Mild Traumatic Brain Injury (MTBI), is defined as a consequence of a physical trauma to the head followed by some disruption of brain function (Parker, 2001). The highest risk age groups for concussion are children up to the age of 5 years and adolescents from 15 years to 19 years of age (CDC, 2010). A constellation of symptoms, dubbed Postconcussion Syndrome (PCS), have been found to be commonly experienced after an individual has suffered a concussion, which consists of cognitive symptoms, affective symptoms, and somatic symptoms that adversely affect the individual\u27s functioning (McAllister & Arciniegas, 2002; Ryan & Warden, 2003; Taylor et al., 2010). These symptoms may last anywhere from two weeks to several years after a concussion has been sustained (Alves, Macciocchi, & Barth, 1993; Ciccerone & Kalmar, 1995; Rutherford, Merrett, & McDonald, 1979; Ryan & Warden, 2003). Research has demonstrated that misconceptions about the nature of concussions and the symptoms that can follow are widespread (Gouvier, Presholdt, & Warner, 1988; Guilmette & Paglia 2004; Willer, Johnson, Rempel, & Linn, 1993). The purpose of this study was to describe the knowledge of a sample of public school teachers regarding concussions and the symptoms that can occur postconcussion. The study investigated common knowledge and misconceptions held by teachers about concussion in children. In addition, the study served an exploratory function and investigated whether differences in misconceptions are evident between various subgroups of teachers. Results of the study indicated public school teachers endorsed very few misconceptions about postconcussion symptoms. Significant differences were found dependent upon the years of experience teaching on the items concerning multi-tasking behaviors, having difficulty concentrating for some time, and emotional problems. No gender differences were found in regards to knowledge and misconceptions of postconcussion symptoms. No significant differences were found dependent upon elementary versus secondary settings. Regular education teachers answered items correctly concerning changes in personality, mood swings, brain damage, and the duration of symptoms at a higher rate than the special education teachers. Finally, both regular education and special education teachers endorse having had training in the area o

    Measurement of limiting activity coefficients using a differential dew point technique

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    Thesis (B.S.) in Chemical Engineering -- University of Illinois at Urbana-Champaign, 1989.Includes bibliographical references (leaf 19)Microfiche of typescript. [Urbana, Ill.]: Photographic Services, University of Illinois, U of I Library, [1989]. 1 microfiche (37 frames): negative.s 1989 ilu n

    Counselling Charles VI of France: Christine de Pizan, Honorat Bovet, Philippe de Mézières, and Pierre Salmon

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    Four vernacular advice books were dedicated to King Charles VI (r. 1380- 1422) during his reign. Charles became king at the age of eleven, and both Philippe de Mézières’ Songe du vieil pelerin and Honorat Bovet’s Arbre des batailles were dedicated to him in 1389, a year after his declaration of personal rule at the age of twenty. Charles VI began suffering from intermittent periods of mental illness from 1392 until his death. Both Christine de Pizan’s Chemin de long estude (1402-3) and Pierre Salmon’s Dialogues (1409, with a second version in 1412-15) were dedicated to him during this period. The four books suggested solutions to problems posed by the king’s minority and later mental illness, as well as other political concerns including the papal schism, the Anglo-French wars, and the conflicts between the king’s relatives that eventually descended into civil war. Although they have been described as belonging to the modern category of “mirrors for princes,” these books are united more by their common dedication to Charles than by their conformity to a modern understanding of genre. The books’ textual contents and their manuscript images, layout, and circulation demonstrate the importance of the dedication to the construction of their messages. The books’ intended audiences included the king as well as other members of his government and in particular his relatives. The writers authorized their advice by stressing the importance of books and their own credentials, especially their goodwill towards and relationship with the king. They adapted familiar discussions of kingship to suggest concrete solutions to the crises in France, and to urge the king’s relatives to work together to support Charles instead of fighting amongst themselves. The later manuscript circulation of these books demonstrates how such a dedication could be adapted for new audiences in different political circumstances

    Patient support interventions to improve adherence to drug-resistant tuberculosis treatment: A counselling toolkit

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    In response to the growing burden of drug-resistant tuberculosis (DR-TB) in South Africa (SA), Médecins Sans Frontières (MSF), with local government health departments, piloted a decentralised model of DR-TB care in Khayelitsha, Western Cape Province, in 2007. The model takes a patient-centred approach to DR-TB treatment that is integrated into existing TB and HIV primary care programmes. One essential component of the model is individual and family counselling to support adherence to and completion of treatment. The structured and standardised adherence support sessions have been compiled into a DR-TB counselling toolkit. This is a comprehensive guide that focuses on DR-TB treatment literacy, adherence strategies to encourage retention in care, and provision of support throughout the patient’s long treatment journey. Along with other strategies to promote completion of treatment, implementation of a strong patient support component of DR-TB treatment is considered essential to reduce rates of loss from treatment among DR-TB patients. We describe our experience from the implementation of this counselling model in a high DR-TB burden setting in Khayelitsha, Cape Town, SA

    The impact of web-based and face-to-face simulation on patient deterioration and patient safety : Protocol for a multi-site multi-method design

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    Background: There are international concerns in relation to the management of patient deterioration which has led to a body of evidence known as the 'failure to rescue' literature. Nursing staff are known to miss cues of deterioration and often fail to call for assistance. Medical Emergency Teams (Rapid Response Teams) do improve the management of acutely deteriorating patients, but first responders need the requisite skills to impact on patient safety. Methods/design: In this study we aim to address these issues in a mixed methods interventional trial with the objective of measuring and comparing the cost and clinical impact of face-to-face and web-based simulation programs on the management of patient deterioration and related patient outcomes. The education programs, known as 'FIRST2ACT', have been found to have an impact on education and will be tested in four hospitals in the State of Victoria, Australia. Nursing staff will be trained in primary (the first 8 min) responses to emergencies in two medical wards using a face-to-face approach and in two medical wards using a web-based version FIRST2ACTWeb. The impact of these interventions will be determined through quantitative and qualitative approaches, cost analyses and patient notes review (time series analyses) to measure quality of care and patient outcomes. Discussion: In this 18 month study it is hypothesised that both simulation programs will improve the detection and management of deteriorating patients but that the web-based program will have lower total costs. The study will also add to our overall understanding of the utility of simulation approaches in the preparation of nurses working in hospital wards. (ACTRN12616000468426, retrospectively registered 8.4.2016). © 2016 The Author(s)

    The Eighteenth Data Release of the Sloan Digital Sky Surveys: Targeting and First Spectra from SDSS-V

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    The eighteenth data release of the Sloan Digital Sky Surveys (SDSS) is the first one for SDSS-V, the fifth generation of the survey. SDSS-V comprises three primary scientific programs, or "Mappers": Milky Way Mapper (MWM), Black Hole Mapper (BHM), and Local Volume Mapper (LVM). This data release contains extensive targeting information for the two multi-object spectroscopy programs (MWM and BHM), including input catalogs and selection functions for their numerous scientific objectives. We describe the production of the targeting databases and their calibration- and scientifically-focused components. DR18 also includes ~25,000 new SDSS spectra and supplemental information for X-ray sources identified by eROSITA in its eFEDS field. We present updates to some of the SDSS software pipelines and preview changes anticipated for DR19. We also describe three value-added catalogs (VACs) based on SDSS-IV data that have been published since DR17, and one VAC based on the SDSS-V data in the eFEDS field.Comment: Accepted to ApJ

    The eighteenth data release of the Sloan Digital Sky Surveys : targeting and first spectra from SDSS-V

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    The eighteenth data release of the Sloan Digital Sky Surveys (SDSS) is the first one for SDSS-V, the fifth generation of the survey. SDSS-V comprises three primary scientific programs, or "Mappers": Milky Way Mapper (MWM), Black Hole Mapper (BHM), and Local Volume Mapper (LVM). This data release contains extensive targeting information for the two multi-object spectroscopy programs (MWM and BHM), including input catalogs and selection functions for their numerous scientific objectives. We describe the production of the targeting databases and their calibration- and scientifically-focused components. DR18 also includes ~25,000 new SDSS spectra and supplemental information for X-ray sources identified by eROSITA in its eFEDS field. We present updates to some of the SDSS software pipelines and preview changes anticipated for DR19. We also describe three value-added catalogs (VACs) based on SDSS-IV data that have been published since DR17, and one VAC based on the SDSS-V data in the eFEDS field.Publisher PDFPeer reviewe

    Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

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    Funding Information: This work was supported by the National Institute of Mental Health / U.S. Army Medical Research and Development Command (Grant No. R01MH106595 [to CMN, IL, MBS, KJRe, and KCK], National Institutes of Health (Grant No. 5U01MH109539 to the Psychiatric Genomics Consortium ), and Brain & Behavior Research Foundation (Young Investigator Grant [to KWC]). Genotyping of samples was provided in part through the Stanley Center for Psychiatric Genetics at the Broad Institute supported by Cohen Veterans Bioscience . Statistical analyses were carried out on the LISA/Genetic Cluster Computer ( https://userinfo.surfsara.nl/systems/lisa ) hosted by SURFsara. This research has been conducted using the UK Biobank resource (Application No. 41209). This work would have not been possible without the financial support provided by Cohen Veterans Bioscience, the Stanley Center for Psychiatric Genetics at the Broad Institute, and One Mind. Funding Information: MBS has in the past 3 years received consulting income from Actelion, Acadia Pharmaceuticals, Aptinyx, Bionomics, BioXcel Therapeutics, Clexio, EmpowerPharm, GW Pharmaceuticals, Janssen, Jazz Pharmaceuticals, and Roche/Genentech and has stock options in Oxeia Biopharmaceuticals and Epivario. In the past 3 years, NPD has held a part-time paid position at Cohen Veterans Bioscience, has been a consultant for Sunovion Pharmaceuticals, and is on the scientific advisory board for Sentio Solutions for unrelated work. In the past 3 years, KJRe has been a consultant for Datastat, Inc., RallyPoint Networks, Inc., Sage Pharmaceuticals, and Takeda. JLM-K has received funding and a speaking fee from COMPASS Pathways. MU has been a consultant for System Analytic. HRK is a member of the Dicerna scientific advisory board and a member of the American Society of Clinical Psychopharmacology Alcohol Clinical Trials Initiative, which during the past 3 years was supported by Alkermes, Amygdala Neurosciences, Arbor Pharmaceuticals, Dicerna, Ethypharm, Indivior, Lundbeck, Mitsubishi, and Otsuka. HRK and JG are named as inventors on Patent Cooperative Treaty patent application number 15/878,640, entitled “Genotype-guided dosing of opioid agonists,” filed January 24, 2018. RP and JG are paid for their editorial work on the journal Complex Psychiatry. OAA is a consultant to HealthLytix. All other authors report no biomedical financial interests or potential conflicts of interest. Funding Information: This work was supported by the National Institute of Mental Health/ U.S. Army Medical Research and Development Command (Grant No. R01MH106595 [to CMN, IL, MBS, KJRe, and KCK], National Institutes of Health (Grant No. 5U01MH109539 to the Psychiatric Genomics Consortium), and Brain & Behavior Research Foundation (Young Investigator Grant [to KWC]). Genotyping of samples was provided in part through the Stanley Center for Psychiatric Genetics at the Broad Institute supported by Cohen Veterans Bioscience. Statistical analyses were carried out on the LISA/Genetic Cluster Computer (https://userinfo.surfsara.nl/systems/lisa) hosted by SURFsara. This research has been conducted using the UK Biobank resource (Application No. 41209). This work would have not been possible without the financial support provided by Cohen Veterans Bioscience, the Stanley Center for Psychiatric Genetics at the Broad Institute, and One Mind. This material has been reviewed by the Walter Reed Army Institute of Research. There is no objection to its presentation and/or publication. The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting true views of the U.S. Department of the Army or the Department of Defense. We thank the investigators who comprise the PGC-PTSD working group and especially the more than 206,000 research participants worldwide who shared their life experiences and biological samples with PGC-PTSD investigators. We thank Mark Zervas for his critical input. Full acknowledgments are in Supplement 1. MBS has in the past 3 years received consulting income from Actelion, Acadia Pharmaceuticals, Aptinyx, Bionomics, BioXcel Therapeutics, Clexio, EmpowerPharm, GW Pharmaceuticals, Janssen, Jazz Pharmaceuticals, and Roche/Genentech and has stock options in Oxeia Biopharmaceuticals and Epivario. In the past 3 years, NPD has held a part-time paid position at Cohen Veterans Bioscience, has been a consultant for Sunovion Pharmaceuticals, and is on the scientific advisory board for Sentio Solutions for unrelated work. In the past 3 years, KJRe has been a consultant for Datastat, Inc. RallyPoint Networks, Inc. Sage Pharmaceuticals, and Takeda. JLM-K has received funding and a speaking fee from COMPASS Pathways. MU has been a consultant for System Analytic. HRK is a member of the Dicerna scientific advisory board and a member of the American Society of Clinical Psychopharmacology Alcohol Clinical Trials Initiative, which during the past 3 years was supported by Alkermes, Amygdala Neurosciences, Arbor Pharmaceuticals, Dicerna, Ethypharm, Indivior, Lundbeck, Mitsubishi, and Otsuka. HRK and JG are named as inventors on Patent Cooperative Treaty patent application number 15/878,640, entitled ?Genotype-guided dosing of opioid agonists,? filed January 24, 2018. RP and JG are paid for their editorial work on the journal Complex Psychiatry. OAA is a consultant to HealthLytix. All other authors report no biomedical financial interests or potential conflicts of interest. Publisher Copyright: © 2021 Society of Biological PsychiatryBackground: Posttraumatic stress disorder (PTSD) is heritable and a potential consequence of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information could enhance the discovery power of PTSD genome-wide association studies (GWASs). Methods: A GWAS on PTSD symptoms was performed in 51 cohorts followed by a fixed-effects meta-analysis (N = 182,199 European ancestry participants). A GWAS of LTE burden was performed in the UK Biobank cohort (N = 132,988). Genetic correlations were evaluated with linkage disequilibrium score regression. Multivariate analysis was performed using Multi-Trait Analysis of GWAS. Functional mapping and annotation of leading loci was performed with FUMA. Replication was evaluated using the Million Veteran Program GWAS of PTSD total symptoms. Results: GWASs of PTSD symptoms and LTE burden identified 5 and 6 independent genome-wide significant loci, respectively. There was a 72% genetic correlation between PTSD and LTE. PTSD and LTE showed largely similar patterns of genetic correlation with other traits, albeit with some distinctions. Adjusting PTSD for LTE reduced PTSD heritability by 31%. Multivariate analysis of PTSD and LTE increased the effective sample size of the PTSD GWAS by 20% and identified 4 additional loci. Four of these 9 PTSD loci were independently replicated in the Million Veteran Program. Conclusions: Through using a quantitative trait measure of PTSD, we identified novel risk loci not previously identified using prior case-control analyses. PTSD and LTE have a high genetic overlap that can be leveraged to increase discovery power through multivariate methods.publishersversionpublishe
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