22 research outputs found

    Acute Q fever in febrile patients in northwestern of Iran

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    <div><p>Background</p><p>Q fever is an endemic disease in different parts of Iran. This study aimed to investigate the prevalence of acute Q fever disease among at-risk individuals in northwestern Iran.</p><p>Methodology</p><p>An etiological study was carried out in 2013 in Tabriz County. A total of 116 individuals who were in contact with livestock and had a nonspecific febrile illness were enrolled in the study. IgG phase II antibodies against <i>Coxiella burnetii</i> were detected using ELISA.</p><p>Principal findings</p><p>The prevalence of acute Q fever was 13.8% (95% confidence interval [CI]: 8.0, 21.0%). Headache (87.5%) and fatigue and weakness (81.3%) were the dominant clinical characteristics among patients whit acute Q fever. Acute lower respiratory tract infection and chills were poorly associated with acute Q fever. Furthermore, 32% (95% CI: 24, 41%) of participants had a history of previous exposure to Q fever agent (past infection). Consumption of unpasteurized dairy products was a weak risk factor for previous exposure to <i>C</i>. <i>burnetii</i>.</p><p>Conclusion</p><p>This study identified patients with acute Q fever in northwestern of Iran. The evidence from this study and previous studies conducted in different regions of Iran support this fact that Q fever is one of the important endemic zoonotic diseases in Iran and needs due attention by clinical physicians and health care system.</p></div

    Funnel plot, using data from the 20 included studies in meta-analysis, with kappa displayed on the horizontal axis and S.E. (kappa) on the vertical axis; symmetrical plot shows the absence of publication bias.

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    <p>Funnel plot, using data from the 20 included studies in meta-analysis, with kappa displayed on the horizontal axis and S.E. (kappa) on the vertical axis; symmetrical plot shows the absence of publication bias.</p
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