Dental Anxiety in Relationship to Demographic Status and Periodontal Health in Adults

WOS: 000446726700007Objective: Dental anxiety is a major complication for many patients and practitioners. Dental fear often results in poor oral health in regard to poor cooperation. The aim of the present study was to determine the dental anxiety and its relation to socio-demographic status and periodontal health in adults. Materials and Methods: In this cross-sectional study, a total of 187 patients were asked to complete a questionnaire consisted of the questions gathering information on sex, age, education level, income level, smoking habits and the last dental visit The questionnaire also included Modified Dental Anxiety scale (MDAS) administered in Turkish language. The oral health status was determined with Community Periodontal index (CPI). Results: Based on MDAS scores, 54% of the subjects had mild anxiety, 41.7% had moderate anxiety, and 4.3% had severe anxiety. Anxiety was affected by age and gender (p0.05). Participants with higher CPI scores had significantly higher dental anxiety compared to those of lower CPI scores (p<0.05). Conclusion: Encouragement of young individuals for regular dental visits since childhood would help to lower the dental anxiety. Frequent dental visits might prevent the negative dental experiences and contribute to decrease the dental fear

Evaluating the Periodontal Status and Oral Hygiene Habits Among Dental Patients

WOS: 000390100700004Objective: The periodontal status is important for treatment planning. The aim of this cross-sectional study was to determine the periodontal status and to explore the relationship between demographic and socio-economic data and smoking and systemic health and oral hygiene habits of subjects who attended Ege University School of Dentistry. Methods: All subjects were interviewed with a structured questionnaire. Gender, educational status, income profit, smoking habits, systemic problems, dental treatment frequency, and oral hygiene habits were recorded using this questionnaire. The periodontal status was evaluated by CPITN and plaque and gingival indexes. Data were analyzed using a statistical program. Results: When periodontal conditions were investigated, 69.5% of the subjects had gingivitis and 30.5% had periodontitis. The tooth brushing habits and frequency of replacing a new toothbrush were significantly different between the gingivitis and periodontitis groups (p< 0.05). CPI values negatively correlated with financial income and education level (p< 0.05). A positive correlation was observed between the level of education and number of existed teeth (p< 0.001). Conclusion: According to our results, subjects showed poor periodontal health and a lack of oral hygiene habits. Our results showed an extremely high demand for periodontal health service programs. The present study indicates a need for oral health promotion including health education along with oral healthcare service provision

Evaluation of gingival crevicular fluid cyclophilin a and extracellular matrix metalloproteinase inducer levels in different periodontal diseases

WOS: 000379369600022PubMed ID: 27176139Objective: Cyclophilin A (CypA) is able to regulate inflammatory responses and matrix metalloproteinase production via its interaction with extracellular matrix metalloproteinase inducer (EMMPRIN). EMMPRIN is the cell surface receptor of CypA. The aim of the present study was to evaluate the gingival crevicular fluid (GCF) CypA and EMMPRIN levels in patients with chronic periodontitis (CP), generalized aggressive periodontitis (G-AgP) and periodontally healthy controls. Methods: Twenty CP patients, 19 G-AgP patients and 20 healthy control subjects were included in the present study. All study participants were non-smokers. Full mouth clinical periodontal parameters including probing depth, clinical attachment level, plaque index, and papilla bleeding index were recorded. GCF CypA and EMMPRIN levels were analyzed by enzyme-linked immunosorbent assay. Data were analyzed statistically with parametric and non-parametric tests. Results: GCF CypA total amount was higher in the G-AgP group compared to healthy controls (p 0.05). No significant difference in GCF CypA total amount between CP and G-AgP was observed (p > 0.05). Also, there was no significant difference in GCF EMMPRIN total amounts among the study groups (p > 0.05). Conclusion: Higher levels of GCF CypA in patients with G-AgP might demonstrate that CypA is associated with the inflammatory infiltrate and alveolar bone destruction of G-AgP. However, GCF CypA level does not seem to be affected by CP. Similar GCF EMMPRIN levels in diseased and healthy groups might suggest that EMMPRIN has role in the turn over of connective tissues in physiological conditions as well as pathological state. (C) 2016 Elsevier Ltd. All rights reserved

LEVELS OF LL-37 ANTIMICROBIAL PEPTIDE IN THE GINGIVAL CREVICULAR FLUID OF YOUNG AND MIDDLE-AGED SUBJECTS WITH OR WITHOUT GINGIVITIS

WOS: 000408113400003PubMed ID: 28955581Purpose: LL-37 is an antimicrobial peptide which plays an important role in the innate immunity. The aim of this study was to investigate the LL-37 levels in the gingival crevicular fluid (GCF) of middle-aged and young adults who have either gingivitis or healthy periodontal tissues. Materials and Methods: Forty middle-aged adults (20 healthy controls and 20 with gingivitis) and 41 younger adults (20 healthy controls and 21 with gingivitis) were included in the present study. Probing depth, clinical attachment level, plaque index, and papilla bleeding index were recorded. LL-37 levels in the GCF were analyzed by enzyme-linked immunosorbent assay. Results: No significant differences were observed in the GCF LL-37 levels between young healthy and middle-aged healthy subjects. Also, there were no significant differences in GCF LL-37 levels between young and middle-aged gingivitis subjects. However, gingivitis groups had significantly higher GCF LL-37 levels than healthy groups (p<0.001). Correlation analysis demonstrated no significant correlation between age and GCF LL-37 levels neither in healthy nor in gingivitis groups. Conclusion: The levels of LL-37 in GCF increase in the presence of gingival inflammation, however, this does not vary according to subjects being young or middle-aged.Ege University Research FoundationEge University [2012/DIS/019]This study has been supported by a research grant from Ege University Research Foundation (project no : 2012/DIS/019)

Monocyte chemotactic protein-1, RANTES and macrophage migration inhibitory factor levels in gingival crevicular fluid of metabolic syndrome patients with gingivitis

WOS: 000381592400011PubMed ID: 27270225Objective: The aim of the present study was to determine gingival crevicular fluid (GCF) levels of monocyte chemotactic protein-1 (MCP-1), regulated on activation, normal T-cell expressed and secreted protein (RANTES) and macrophage migration inhibitory factor (MIF) in metabolic syndrome patients with gingivitis. Design: Twenty metabolic syndrome patients with gingivitis (MSG), 20 MetS patients with clinically healthy periodontium (MSH), 20 systemically healthy subjects with gingivitis and 20 subjects who were both systemically and periodontally healthy were included. Periodontal and systemical parameters were recorded. GCF MCP-1, RANTES and MIF levels were assayed by enzyme-linked immunosorbent assay method. Results: MSG and MSH groups had elevated blood pressure, triglyceride, waist circumference and fasting glucose values in comparison to gingivitis and healthy groups (P 0.05). Conclusion: Elevated levels of GCF RANTES in MetS patients with gingivitis might associate with the presence of increased gingival inflammation by MetS. Low-grade systemic inflammation associated with MetS and adipose tissue-derived RANTES might lead to altered GCF RANTES levels in the presence of gingival inflammation. (C) 2016 Published by Elsevier Ltd.Ege University Research ProjectEge University [06-DIS-013]This work was supported by grants from the Ege University Research Projects number: 06-DIS-013