42,299 research outputs found
PUSAT PEMBINAAN ATLET BOLA VOLI KOTA BANDUNG
Olahraga bola voli di Kota Bandung semakin berkembang ditandai dengan bermunculannya klub pembinaan baru, namun perkembangan tersebut tidak didukung dengan fasilitas pelatihan yang memadai sebagai penunjang keberlangsungan kegiatan pelatihan. “Pusat Pembinaan Atlet Bola Voli di Kota Bandung” merupakan wadah bagi perkembangan olahraga bola voli di Kota Bandung dengan mewadahi beberapa klub pembinaan bola voli di Kota Bandung dan mawadahi penyelenggaraan event pertandingan olahraga bola voli tingkat klub, daerah dan nasional. Dengan sistem pelatihan yang terkoordinasi melalui penyediaan fasilitas yang terintegrasi bagi atlet seperti fasilitas pelatihan, fasilitas pertandingan, dan fasilitas akomodasi (asrama). Fasilitas pelatihan berupa lapangan bola voli, penunjang pelatihan berupa ruang fisik (indoor dan outdoor) dan sekretariat klub, asrama, kafetaria dan retail retail komersil. Pengolahan struktur bentang lebar yang akan diterapkan pada perancangan ini, dijadikan sebagai pembentuk ruang baik interior maupun eksterior. Penggunaan struktur ini dapat menjadi estetika dan daya tarik pada perancangan ini.----------The sport of volleyball in Bandung growing, marked by the emergence of a new coaching club, but these developments are not supported by adequate training facilities as supporting the continuity of training activities. "Pusat pembinaan Atlet Bola Voli di Kota Bandung" is a forum for the development of the sport of volleyball in Bandung, by facilitating some coaching club volleyball in Bandung and facilitated a match event sport volleyball club level, regional and national levels. With coordinated training systems through the provision of integrated facilities for athletes, such as training facilities, games facilities, and accommodation facilities (boarding). Training facilities such as volleyball courts, supporting the training in the form of physical space (indoor and outdoor) and the secretariat of the club, dormitories, cafeterias and commercial retail. The use of wide-span structure that will be implemented in this design, be used as a space forming both interior and exterior. The use of this structure can be aesthetic and appeal to this design
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The effect of eicosapentaenoic acid on brain and platelet produced bioactive lipid mediators. The effect of eicosapentaenoic acid, docosapentaenoic acid and other polyunsaturated fatty acids on the eicosanoids and endocannabinoids produced by rat brain and human platelets using electrospray ionisation tandem mass spectrometry-based analysis.
Eicosapentaenoic acid (EPA) is a polyunsaturated fatty acid (PUFA) with neuroprotective and cardioprotective properties. It is thought that some of the actions of EPA may be attributed to its elongated metabolite, the PUFA docosapentaenoic acid (DPA). Docosahexaenoic acid (DHA) and arachidonic acid (AA) are bioactive PUFA ubiquitously expressed in neural tissues. EPA and AA can be converted by cyclooxygenase (COX) to prostanoids and by lipoxygenase (LOX) to hydroxy fatty acids. PUFA can also be converted to ethanolamides in the brain. These mediators are involved in physiological and pathological processes in many bodily systems.
The purpose of this study was to examine the production of eicosanoids, hydroxy fatty acids and fatty acid ethanolamides in young and aged rat brain following EPA or DPA enriched diets. The effects of specific PUFA on human platelet eicosanoid production were also investigated as these mediators play a role in adhesion and aggregation. Liquid chromatography coupled to tandem mass spectrometry (LC/ESI-MS/MS) assays were developed and used to measure lipid mediators in rat brain and human platelets.
Ageing in rat brain was accompanied with several changes in the prostanoid and hydroxy fatty acid profiles. Supplementing the diet with EPA or DPA at a daily dose of 200 mg/kg for 8 weeks prevented these changes and decreased levels of PGE2. DPA changed the profile of hydroxy fatty acids synthesised in the brain tissue of young animals. This study has shown that levels of eicosapentaenoylethanolamide (EPA-EA) increase in the brain as a result of ageing and that this is accompanied by an increase in levels of anandamide. Feeding aged animals EPA or DPA further increased the levels of EPA-EA but prevented any change in the level of anandamide.
Niacin is used to treat hypercholesterolaemia although it is associated with an unpleasant PGD2 mediated skin flush. This exploratory study has shown that human platelets treated with niacin did not show any changes in their prostanoid and hydroxy fatty acid profiles. Platelets treated with EPA showed increased production of TXB3 and 12-HEPE. Niacin augmented the effects of EPA on human platelet mediator synthesis.
Overall, this study has demonstrated that EPA can change brain and platelet lipid mediator synthesis and has provided evidence that could explain some of the neuroprotective and cardioprotective actions of this PUFA
Real-time monitoring of healthy omega-3 production in micro-algae: A viability study
Eicosapentaenoic acid (EPA) is an omega 3 fatty-acid essential to humans, who mainly rely on fish oil as a source of EPA. Unfortunately, this is not a sustainable source
Fighting for Pollution Cleanup in a Company Town: Silver Valley People's Action Coalition
Barbara Miller and a coalition of local activists, members of the Silver Valley People's Action Coalition (SVPAC), address the environmental and health consequence of 100 years of mining in Idaho's Silver Valley. They are up against the physical damage wrought by lead poisoning as well as community members' deep reluctance to speak out against the mining companies that had such a hold on the community
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