421 research outputs found
The Characterization of Earth Sediments using Radiative Transfer Models from Directional Hyperspectral Reflectance
Remote sensing techniques are continuously being developed to extract physical information about the Earth’s surface. Over the years, space-borne and airborne sensors have been used for the characterization of surface sediments. Geophysical properties of a sediment surface such as its density, grain size, surface roughness, and moisture content can influence the angular dependence of spectral signatures, specifically the Bidirectional Reflectance Distribution Function (BRDF). Models based on radiative transfer equations can relate the angular dependence of the reflectance to these geophysical variables. Extraction of these parameters can provide a better understanding of the Earth’s surface, and play a vital role in various environmental modeling processes. In this work, we focused on retrieving two of these geophysical properties of earth sediments, the bulk density and the soil moisture content (SMC), using directional hyperspectral reflectance. We proposed a modification to the radiative transfer model developed by Hapke to retrieve sediment bulk density. The model was verified under controlled experiments within a laboratory setting, followed by retrieval of the sediment density from different remote sensing platforms: airborne, space-borne and a ground-based imaging sensor. The SMC was characterized using the physics based multilayer radiative transfer model of soil reflectance or MARMIT. The MARMIT model was again validated from experiments performed in our controlled laboratory setting using several different soil samples across the United States; followed by applying the model in mapping SMC from imagery data collected by an Unmanned Aerial System (UAS) based hyperspectral sensor
Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer\u27s disease
A promising new therapeutic target for the treatment of Alzheimer\u27s disease (AD) is the circadian system. Although patients with AD are known to have abnormal circadian rhythms and suffer sleep disturbances, the role of the molecular clock in regulating amyloid-beta (Aβ) pathology is still poorly understood. Here, we explored how the circadian repressors REV-ERBα and β affected Aβ clearance in mouse microglia. We discovered that, at Circadian time 4 (CT4), microglia expressed higher levels of the master clock protein BMAL1 and more rapidly phagocytosed fibrillary A
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E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes.
Objective: Since the introduction in 2004, global usage of e-cigarettes (ECs) has risen exponentially. However, the risks of ECs on oral health are uncertain. The purpose of this study is to understand if EC aerosol exposure impacts the gene pathways of normal human oral keratinocytes (NHOKs), particularly the unfolded protein response (UPR) pathway. Materials and methods: EC aerosols were generated reproducibly with a home-made puffing device and impinged into the culture medium for NHOKs. DNA microarrays were used to profile the gene expression changes in NHOKs treated with EC aerosols, and the Ingenuity Pathway Analysis (IPA) was used to reveal signaling pathways altered by the EC aerosols. Quantitative PCR was used to validate the expression changes of significantly altered genes. Results: DNA microarray profiling followed by IPA revealed a number of signaling pathways, such as UPR, cell cycle regulation, TGF-β signaling, NRF2-mediated oxidative stress response, PI3K/AKT signaling, NF-κB signaling, and HGF signaling, activated by EC aerosols in NHOKs. The UPR pathway genes, C/EBP homologous protein (CHOP), activating transcription factor 4 (ATF4), X box binding protein 1 (XBP1), and inositol-requiring enzyme 1 alpha (IRE1α) were all significantly up-regulated in EC aerosol-treated NHOKs whereas immunoglobulin heavy-chain binding protein (BIP) and PRKR-like ER kinase (PERK) were slightly up-regulated. qPCR analysis results were found to be well correlated with those from the DNA microarray analysis. The most significantly changed genes in EC aerosol-treated NHOKs versus untreated NHOKs were CHOP, ATF4, XBP1, IRE1α and BIP. Meanwhile, Western blot analysis confirmed that CHOP, GRP78 (BIP), ATF4, IRE1α and XBP1s (spliced XBP1) were significantly up-regulated in NHOKs treated with EC aerosols. Conclusion: Our results indicate that EC aerosols up-regulate the UPR pathway genes in NHOKs, and the induction of UPR response is mediated by the PERK - EIF2α - ATF4 and IRE1α - XBP1 pathways
Artificial infestations of Tapinanthus ogowensis (Engler) Danser (Loranthaceae) on three host species in the Logbessou Plateau (Douala, Cameroon)
In Cameroon today, Loranthaceae has become a major pest against which a great “battle” must be launched if food production in the country has to be maintained at a self-sufficient level. However, aneffective battle against pests can only be achieved through a better understanding of their geographical distribution and biology. Eight Loranthaceae species (Globimetula braunii, Globimetula dinklagei,Globimetula opaca, Helixanthera mannii, Phragmanthera capitata, Tapinanthus globiferus, Tapinanthus ogowensis, and Tapinanthus preussii) have been identified in the Douala area. Among these species, T. ogowensis is the only one limited to a surface area of about eight hectares in the Logbessou plateau located in a direction of North-East from Douala (Latitude 03°40 - 04°11' N, Longitude 09°16' - 09°52' E,and at an altitude of 13 m). In this zone, the hemi-parasite infests only one host tree (Dacryodes edulis) in the orchards, gardens and agricultural plantations. The hemiparasite is however common andadapted to all the different ecological regions in the southern part Cameroon where it infests several host trees. In order to study the stages involved in the germination, fixation, as well as the initial stagesinvolved in the development of the seedlings of T. ogowensis, three of the most frequent host species (D. edulis, Mangifera indica and Persea americana) on the plateau were artificially infected. The resultsrevealed that the host species are sensitive to the parasite, T. ogowensis, at least during their early stages of growth and development. D. edulis is the most sensitive host species with a 22% yield ofyoung seedlings as against 5 and 4% for P. americana and M. indica, respectively. This sensitivity of the mango tree to T. ogowensis had never been demonstrated before. The percentages of seedsgerminating on the different host species however remained high; 96% on both D. edulis and M. indica and 93% on P. americana. It was also revealed that the development of the young seedlings of T.ogowensis is greatly influenced by the availability of light, a plausible reason why Loranthaceae occupies mainly the uppermost branches of the oldest trees found here
Retrieval of Salt Marsh Above-ground Biomass From High-spatial Resolution Hyperspectral Imagery Using PROSAIL
Salt marsh vegetation density varies considerably on short spatial scales, complicating attempts to evaluate plant characteristics using airborne remote sensing approaches. In this study, we used a mast-mounted hyperspectral imaging system to obtain cm-scale imagery of a salt marsh chronosequence on Hog Island, VA, where the morphology and biomass of the dominant plant species, Spartina alterniflora, varies widely. The high-resolution hyperspectral imagery allowed the detailed delineation of variations in above-ground biomass, which we retrieved from the imagery using the PROSAIL radiative transfer model. The retrieved biomass estimates correlated well with contemporaneously collected in situ biomass ground truth data ( R2=0.73 ). In this study, we also rescaled our hyperspectral imagery and retrieved PROSAIL salt marsh biomass to determine the applicability of the method across spatial scales. Histograms of retrieved biomass changed considerably in characteristic marsh regions as the spatial scale of the imagery was progressively degraded. This rescaling revealed a loss of spatial detail and a shift in the mean retrieved biomass. This shift is indicative of the loss of accuracy that may occur when scaling up through a simple averaging approach that does not account for the detail found in the landscape at the natural scale of variation of the salt marsh system. This illustrated the importance of developing methodologies to appropriately scale results from very fine scale resolution up to the more coarse-scale resolutions commonly obtained in airborne and satellite remote sensing
A Comparison of the Intrinsic Shapes of Two Different Types of Dwarf Galaxies: Blues Compact Dwarfs and Dwarf Ellipticals
We measure the apparent shapes for a sample of 62 blue compact dwarf galaxies
(BCDs), and compare them with the apparent shapes for a sample of 80 dwarf
elliptical galaxies (dEs). The BCDs are flatter, on average, than the dEs, but
the difference is only marginally significant. We then use both non-parametric
and parametric techniques to determine possible distributions of intrinsic
shapes for the BCDs. The hypothesis that BCDs are oblate spheroids can be ruled
out with a high confidence level (), but the hypothesis that they are
prolate spheroids cannot be excluded. The apparent shapes of BCDs are totally
consistent with the hypothesis that they are triaxial ellipsoids. If the
intrinsic axis ratios, and , are distributed according to a
Gaussian with means and and standard deviation ,
we find the best-fitting distribution for BCDs has , while that for dEs has . Our results are consistent with the hypothesis that BCDs
have a close evolutionary relation with dEs.Comment: total 23 pages, 9 figures, and 1 Table, submitted to ApJ on Sep 19
1997. Email addresses: [email protected],
[email protected], [email protected],
[email protected], [email protected]
Shifting Home Energy Consumption Through a Holistic Understanding of the Home System of Practice
This chapter describes the concept of the home system of practice, which can be used to provide a deeper understanding of the social system of the home and inform long-term solutions for enabling domestic energy reduction. More traditional methods have attempted to persuade occupants to change behaviour through the use of information campaigns and feedback technology. However, these interventions are usually short lived as they ignore the underlying reasons for practices to occur. A more effective solution is through practice-oriented design, which co-creates innovative technology with the user. In addition, the emergence and use of automated technology enables practices to act independently of the user. Yet, the success of automation is also reliant on an understanding of the home system of practice, occupant needs and skills
UBVI Surface Photometry of the Spiral Galaxy NGC 300 in the Sculptor Group
We present UBVI surface photometry for 20.'5 X 20.'5 area of a late-type
spiral galaxy NGC 300. In order to understand the morphological properties and
luminosity distribution characteristics of NGC 300, we have derived isophotal
maps, surface brightness profiles, ellipticity profiles, position angle
profiles, and color profiles. By merging the I-band data of our surface
brightness measurements with those of Boeker et al. (2002) based on Hubble
Space Telescope observations, we have made combined I-band surface brightness
profiles for the region of 0."02 < r < 500" and decomposed the profiles into
three components: a nucleus, a bulge, and an exponential disk.Comment: 16 pages(cjaa209.sty), Accepted by the Chinese J. Astron. Astrophys.,
Fig 2 and 8 are degraded to reduce spac
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