Clonality and Antimicrobial Susceptibility of Burkholderia cepacia complex Isolates Collected from Cystic Fibrosis Patients during 1998-2013 in Bern, Switzerland.

For the first time, we analyzed the clonality and susceptibility of Burkholderia cepacia complex isolates (n=55) collected during 1998-2013 from 44 Swiss cystic fibrosis (CF)-patients. B. cenocepacia (n=28) and B. multivorans (n=14) were mainly of sequence type (ST) 833 and ST874, respectively; B. contaminans isolates were of ST102. Overall, the following MIC50/90s (mg/l) were obtained: piperacillin/tazobactam (≤ 4/≥ 128), ticarcillin/clavulanate (≥ 256/≥256), ceftazidime (2/≥ 32), aztreonam (16/≥ 32), meropenem (2/8), tobramycin (8/≥ 16), minocycline (≤ 1/16), levofloxacin (≤ 0.5/≥ 16), and trimethoprim/sulfamethoxazole (≤ 0.5/4). This is the first survey providing information on the clonality of Bcc detected in Switzerland. Species identification and antimicrobial susceptibility tests should always be routinely performed to adapt more targeted therapies

Observation of the associated production of a single top quark and a W boson in pp collisions at s\sqrt{s} = 8 TeV

The first observation of the associated production of a single top quark and a $W$ boson is presented. The analysis is based on a data set corresponding to an integrated luminosity of $12.2\text{}\text{}{\mathrm{fb}}^{-1}$ of proton-proton collisions at $\sqrt{s}=8\text{}\text{}\mathrm{TeV}$ recorded by the CMS experiment at the LHC. Events with two leptons and a jet originating from a $b$ quark are selected. A multivariate analysis based on kinematic and topological properties is used to separate the signal from the dominant $t\overline{t}$ background. An excess consistent with the signal hypothesis is observed, with a significance which corresponds to 6.1 standard deviations above a background-only hypothesis. The measured production cross section is $23.4±5.4\text{}\text{}\text{pb}$, in agreement with the standard model prediction