18 research outputs found
Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98 of the human histamine H4 receptor
Background and Purpose The recently proposed binding mode of 2-aminopyrimidines to the human (h) histamine
Bispyrimidines as potent histamine H4 receptor ligands: delineation of structure activity relationships and detailed H4 receptor binding mode
The basic methylpiperazine moiety is considered a necessary substructure for high histamine