Hybrid clear cell odontogenic carcinoma and ameloblastic carcinoma-report of a case

Ameloblastic carcinoma (AC) produces extensive local destruction, perforation of the cortical plate, extension into surrounding soft tissues, numerous recurrent lesions, and metastasis, usually to cervical lymph nodes. Clear cell odontogenic carcinoma (CCOC) which was previously designated clear cell odontogenic tumor also exhibits an aggressive biologic behavior and a tendency to metastasize to distant locations. Both lesions are rare. We report an odontogenic carcinoma with a dual histomorphologic feature of CCOC and AC coexisting in a single lesion. To the best of our knowledge, this is the first report of its kind in the literature

Cost-return analysis of cocoyam marketing in Nsukka agricultural zone of Enugu State, Nigeria

This research was carried out to ascertain the cost-return of cocoyam marketing in Nsukka Agricultural Zone, Enugu State. Primary and secondary data were collected. Primary data were collected with the use of structured questionnaire from sixty (60) respondents. Data obtained were analysed using appropriate economic and statistical tools. Other analytical tools used were gross margin and benefit cost ratio. From the result obtained, female dominate males in cocoyam marketing and are people within the age range of 41 -50 years. The results also shows that 80% of the respondents had their formal education and have 5 years and above of experience in the marketing system. The research further discovered that there are four different market channels of distribution of cocoyam from the producers to the consumers in the marketing system. It was also found that the highest annual income generated is within the range of N21, 000 -N 25,000 in the study area. The results also show those cocoyam marketers were in union which comprises both wholesalers and retailers and they do not fix the price but influence the price of cocoyam. .The results from the gross margin and benefit cost ratio shows that the enterprise is profitable. The study showed that small-holder cocoyam enterprise is profitable by returning 1.1 for every N1.0 spent. The research also identified that the major problem encountered in cocoyam marketing were lack of credit facilities, high transportation cost, lack of storage facilities, poor handling, and high market charges, among others. The researcher recommends among others that these are need for stakeholders to come up with the best storage facilities for the cocoyam producers. There is need for credit assistance for the cocoyam marketers without high collateral. There is need for good road network in the rural areas and minimization of market charges

WHAT WE HEAR AND WHAT WE DO: An analysis of the perceptual influence of child spacing campaigns on the knowledge, attitude and practices of rural women in South-East Nigeria

This study examines the influence of child spacing campaigns on the knowledge, attitude and practices of South-East rural women. Using behavioural change theory as the framework, the study adopted survey method as its research design. A total of 384 respondents drawn from the South-East responded to the copies of the questionnaire designed from six research questions raised in the study. After a thorough analysis, it was found that while the mass media campaigns on child spacing have created serious awareness about child spacing in South-East rural communities, the practice is still very low. Some of the problems found to be associated with this low practice include lack of adequate community health facilitators, lack of information on improved child spacing techniques, urban oriented messages, lack of integration of the rural people in messages/communication meant for their consumption, etc. Based on these findings, it was recommended that, health workers, media researchers, communicators, social workers, guidance counselors and those in the helping profession should take cognizance of those variables that have been found to influence birth spacing practices among couples with the view to correcting them for an informed and healthy society. Keywords: Child spacing ●Campaign● Attitude ● Practices●  Rural wome

Using Taylorism to make work easier: A work procedure perspective

Background: Complexities generally are conundrums that inhibit efficiency and effectiveness in research and practice; one of the symptoms of this is nebulous obstruction to task completion in the workplace. Complexities in work procedures create complications in the application of procedures for completing tasks. Recent trends in the Auditor General’s report have demonstrated the metastasising culture of non-compliance to work procedures in municipalities in South Africa. Research, as well as the audit outcomes for the Eastern Cape in particular, is a testament to this assertion. Therefore, there is no need to make work more complex.   Aim: To ascertain whether the application of Taylorism in the workplace could improve performance and to access the utilisation of work procedure in municipalities in the Eastern Cape.   Setting: This study was carried out using quantitative data collected from a District Municipality and its five local municipalities at the Transkei area of the Eastern Cape, South Africa.   Method: A survey completed by 593 municipality workers (junior workers) was collected and analysed using statistical methods and triangulation.   Results: Findings from the article reveals that work procedures in the organisation might be old and archaic. It may be relevant to workers who have little or no interference from externalities with regard to their job commitments. It recommends that those officials that perform routinised functions in municipalities should use a work procedure manual when completing their task. Based on the notion that work procedures engender compliance, increase outcome and output, increase productivity, save time, reduce stress and organisational friction or conflict in organisations.   Conclusion: It concludes that procedures that are comprehensible (simple), accessible (organically inputted and communicated) and accurate (effectively designed) will improve the daily functionality of lower echelon staff in the municipalities, especially those requiring little or no external influence on the completion of a task

Paratesticular myxoid liposarcoma in a 23-year old Nigerian

Paratesticular liposarcomas are rare tumors and are usually seen in patients in middle age or older. Optimal treatment is radical orchidectomy. Radiotherapy or chemotherapy is added for advanced disease or recurrences. These practice guidelines often vary from the experience in developing countries

Adsorption and corrosion inhibition characteristics of 2–(chloromethyl) benzimidazole for C1018 carbon steel in a typical sweet corrosion environment: Effect of chloride ion concentration and temperature

Benzimidazole derivatives are emerging as promising corrosion inhibitors for oil and gas application because they exhibit high efficiency and very good environmental profile. Although long alkyl and phenyl chains enhance their efficiency, they also increase their toxicity. Finding benzimidazole derivatives devoid of long hydrocarbon chains and with lower toxicity has become a priority. 2–(chloromethyl)benzimidazole (CMB), with log Po/w = 2.2, has been investigated as a promising low-toxic sweet corrosion inhibitor for C1018 carbon steel in CO2–saturated NaCl solution under static condition using experimental and theoretical approaches. At 25 ◦C, Open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), and potentiodynamic polarization (PDP) techniques confirm that CMB is an anodic-type sweet corrosion inhibitor which is able to form a protective layer on the steel surface and provide inhibition efficiency of 97.54% at 10 ppm. The efficiency increased to 98.40% and 98.58% upon increasing the temperature to 40 ◦C and 60 ◦C, respectively but decreased to 96.32% and 94.76% as the salt concentration was raised to 5.0% and 7.0% NaCl, respectively. The latter was attributed to the antagonistic competition between Cl– ions and CMB for anodic adsorption. The CMB–steel interaction is facilitated by the free electrons around N heteroatoms and C = C bonds, based on FTIR analysis and computational calculations. This eventually ameliorates the surface degradation of the steel during the sweet corrosion at 25 and 60 ◦C. CMB performance is highly comparable with reported sweet corrosion inhibitors with higher toxicity values

The Design of an Integrated Crude Oil Distillation Column with Submerged Combustion Technology

Generally, Petroleum refineries are put in place to convert or refine unprocessed crude oil into more useful products using both physical separation and chemical conversion processes. Albeit, different refining unit are subsets of the physical separation category. The atmospheric and vacuum distillation unit seems to be more prominent. Conventionally, the crude atmospheric residue cannot be further heated in an atmospheric condition due to: coke formation, pipes plugging, thermal cracking and straining of the furnace. A vacuum distillation column is therefore required. Methods: This study, therefore, focuses on the limitations, “over straining of the furnace to provide the necessary heat” and “non-reliance on the additional re-boiler since it only acts as a heat exchanger”. An integrated distillation column with a capacity of 10,000 barrel per day was therefore designed for the concurrent production of all distillate cuts. Results: This was achieved through the introduction of a submerged combustion zone at the stripping section of the column where Naphtha was utilized as the source of fuel. Verification of this approach was also conducted using Autodesk invention software and a finite element analysis tool to evaluate both thermal and computational fluid analysis impact. Overall, all derived distilled products met the American Society for Testing and Material Standard Table 6

Use of mixed methods designs in substance research: a methodological necessity in Nigeria

The utility of mixed methods (qualitative and quantitative) is becoming increasingly accepted in health sciences, but substance studies are yet to substantially benefit from such utilities. While there is a growing number of mixed methods alcohol articles concerning developed countries, developing nations are yet to embrace this method. In the Nigerian context, the importance of mixed methods research is yet to be acknowledged. This article therefore, draws on alcohol studies to argue that mixed methods designs will better equip scholars to understand, explore, describe and explain why alcohol consumption and its related problems are increasing in Nigeria. It argues that as motives for consuming alcohol in contemporary Nigeria are multiple, complex and evolving, mixed method approaches that provide multiple pathways for proffering solutions to problems should be embraced

Selfing revealed potential for higher yield performance than backcrossing among tomato segregating populations of Solanum lycopersicum × S. pimpinellifolium crosses under tropical humid climate

The objectives of this study were to assess and identify new source of phenotypic variability among F3 and BC1F2 tomato populations, and apply genotype by yield*trait (GYT) biplots for population and line selection based on multiple traits. Four diverse cultivated parents (‘CLN2498D’ [D] and ‘CLN2417H’ [H] from Ethiopia; ‘UC Dan INDIA’ [U] and ‘Tima’ [T] from Nigeria), and wild parent ‘LA2093’ [W] were used to generate 276 potential breeding lines. The lines were categorized into eight populations (‘pop_1_W/H1’, ‘pop_2_W/H2’, ‘pop_3_W/D1’, ‘pop_4_W/D2’, ‘pop_5_W/T1’, ‘pop_6_W/T2’, ‘pop_7_W/U1’, and ‘pop_8_W/U2’), and evaluated twice in the field using 19 × 15 alpha-lattice design with two replicates. Significant differences were observed among lines and populations for all yield enhancing traits. ‘Pop_1_W/H1’, ‘pop_4_W/D2’ and ‘pop_6_W/T2’ expressed the highest genetic divergence for plant height, number of leaves, total flower and fruit number, and fruit weight. GYT biplots revealed that all yield*trait interactions had a positive correlation with each other. F3 populations, ‘pop_5_W/T1’ and ‘pop_1_W/H1’ exhibited the best performance for majority of the yield*trait combinations. Hierarchical clustering on principal components (HCPC) revealed overlapping lines (70.58% of Cluster D lines) and (54.05% of Cluster U lines) from the two F3 populations. In BC1F2 population, 32.35% of the 34 original lines of Cluster D and 48.48% of Cluster T lines overlapped between Clusters D and T, while 18.18% of Cluster T lines and 8.82% of Cluster H lines were transgressive between Clusters T and H. Transgressive segregants ‘0210U1’, ‘0211U1’, and ‘0171T1’ of selfed population using multivariate analysis were believed to represent potential sources of novel genetic variation for future tomato breeding

Novel <i>IRF6 </i>mutations in families with Van Der Woude syndrome and popliteal pterygium syndrome from sub-Saharan Africa

Orofacial clefts (OFC) are complex genetic traits that are often classified as syndromic or nonsyndromic clefts. Currently, there are over 500 types of syndromic clefts in the Online Mendelian Inheritance in Man (OMIM) database, of which Van der Woude syndrome (VWS) is one of the most common (accounting for 2% of all OFC). Popliteal pterygium syndrome (PPS) is considered to be a more severe form of VWS. Mutations in the IRF6 gene have been reported worldwide to cause VWS and PPS. Here, we report studies of families with VWS and PPS in sub-Saharan Africa. We screened the DNA of eight families with VWS and one family with PPS from Nigeria and Ethiopia by Sanger sequencing of the most commonly affected exons in IRF6 (exons 3, 4, 7, and 9). For the VWS families, we found a novel nonsense variant in exon 4 (p.Lys66X), a novel splice-site variant in exon 4 (p.Pro126Pro), a novel missense variant in exon 4 (p.Phe230Leu), a previously reported splice-site variant in exon 7 that changes the acceptor splice site, and a known missense variant in exon 7 (p.Leu251Pro). A previously known missense variant was found in exon 4 (p.Arg84His) in the PPS family. All the mutations segregate in the families. Our data confirm the presence of IRF6-related VWS and PPS in sub-Saharan Africa and highlights the importance of screening for novel mutations in known genes when studying diverse global populations. This is important for counseling and prenatal diagnosis for high-risk families