The Ages and Abundances of the M87 Globular Clusters

A subset of 150 globular clusters in M87 has been selected on the basis of S/N ratio for abundance and age determinations from the sample of Paper I. Indices measuring the strength of the strongest spectral features were determined for the M87 GCs and from new data for twelve galactic GCs. Combining the new and existing data for the galactic GCs and comparing the $(U-R)$ colors and the line indices gives qualitative indications for the ages and abundances of the GCs. Quantitative results are obtained by applying the Worthey (1994) models for the integrated light of stellar systems of a single age, calibrated by observations of galactic GCs, to deduce abundances and ages for the objects in our sample. We find that the M87 GCs span a wide range in metallicity, from very metal poor to somewhat above solar metallicity. The mean [Fe/H] of -0.95 dex is higher than that of the galactic GC system, and there is a metal rich tail that reaches to higher [Fe/H] than one finds among the galactic GCs. The mean metallicity of the M87 GC system is about a factor of four lower than that of the M87 stellar halo at a fixed projected radius $R$. The metallicity inferred from the X-ray studies is similar to that of the M87 stellar halo, not to that of GCs. We infer the relative abundances of Na, Mg, and Fe in the M87 GCs from the strength of their spectral features. The behavior of these elements between the metal rich and metal poor M87 GCs is similar to that shown by the galactic GCs and by halo stars in the Galaxy. The pattern of chemical evolution in these disparate old stellar systems is indistinguishable. We obtain a median age for the M87 GC system of 13 Gyr, similar to that of the galactic GCs, with a small dispersion about this value.Comment: 56 pages with included postscript figures; added derived M87 GC metallicities to Table 2, a statistical analysis of possible bimodality, an appendix on the metallicity calibration of U-R and the Washington system, and other smaller changes. Accepted for publication in ApJ. (See paper for complete version of the Abstract.

The Surface Brightness Fluctuations and Globular Cluster Populations of M87 and its Companions

Using the surface brightness fluctuations in HST WFPC-2 images, we determine that M87, NGC 4486B, and NGC 4478 are all at a distance of ~16 Mpc, while NGC 4476 lies in the background at ~21 Mpc. We also examine the globular clusters of M87 using archived HST fields. We detect the bimodal color distribution, and find that the amplitude of the red peak relative to the blue peak is greatest near the center. This feature is in good agreement with the merger model of elliptical galaxy formation, where some of the clusters originated in progenitor galaxies while other formed during mergers.Comment: 5 pages, 2 figure

Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen

The ways that fibroblasts remodel their environment are central to wound healing, development of musculoskeletal tissues, and progression of pathologies such as fibrosis. However, the changes that fibroblasts make to the material around them and the mechanical consequences of these changes have proven difficult to quantify, especially in realistic, viscoelastic three-dimensional culture environments, leaving a critical need for quantitative data. Here, we observed the mechanisms and quantified the mechanical effects of fibroblast remodeling in engineered tissue constructs (ETCs) comprised of reconstituted rat tail (type I) collagen and human fibroblast cells. To study the effects of remodeling on tissue mechanics, stress-relaxation tests were performed on ETCs cultured for 24, 48, and 72 h. ETCs were treated with deoxycholate and tested again to assess the ECM response. Viscoelastic relaxation spectra were obtained using the generalized Maxwell model. Cells exhibited viscoelastic damping at two finite time constants over which the ECM showed little damping, approximately 0.2 s and 10-30 s. Different finite time constants in the range of 1-7000 s were attributed to ECM relaxation. Cells remodeled the ECM to produce a relaxation time constant on the order of 7000 s, and to merge relaxation finite time constants in the 0.5-2 s range into a single time content in the 1 s range. Results shed light on hierarchical deformation mechanisms in tissues, and on pathologies related to collagen relaxation such as diastolic dysfunction. Statement of Significance As fibroblasts proliferate within and remodel a tissue, they change the tissue mechanically. Quantifying these changes is critical for understanding wound healing and the development of pathologies such as cardiac fibrosis. Here, we characterize for the first time the spectrum of viscoelastic (rate-dependent) changes arising from the remodeling of reconstituted collagen by fibroblasts. The method also provides estimates of the viscoelastic spectra of fibroblasts within a three-dimensional culture environment. Results are of particular interest because of the ways that fibroblasts alter the mechanical response of collagen at loading frequencies associated with cardiac contraction in humans. © 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved

Alignment-based optically pumped magnetometer using a buffer gas cell

Alignment-based optically pumped magnetometers (OPMs) are capable of measuring oscillating magnetic fields with high sensitivity in the fT/sqrt(Hz) range. Until now, alignment-based magnetometers have only used paraffin-coated vapour cells to extend the spin relaxation lifetimes of the alkali vapour. The drawback of these cells is that they are hand-blown and are therefore time-intensive, and somewhat unreliable, to produce. Buffer gas cells, on the other hand, can be manufactured on a mass scale using microfabrication techniques. We present the first demonstration of an alignment-based magnetometer using a buffer gas vapour cell containing caesium (Cs) alkali vapour and nitrogen (N2) buffer gas. The OPM is operated at 55 degrees C and we achieve a 325 fT/sqrt(Hz) sensitivity to 10 kHz oscillating magnetic fields with an 800 Hz bandwidth. The alignment-based magnetometer uses a single laser beam for optical pumping and probing and could potentially allow for more rapid commercialisation of radio-frequency OPMs, due to the robustness of the one-beam geometry and the potential for mass-scale microfabrication of buffer gas cells.Comment: 10 pages, 7 figure