Coagulation Disorder following Red Clover (Trifolium Pratense) Misuse: a Case Report

Introduction: An increasing variety of alternative health care products and supplements known as over-the-counter (OTC) or non-prescription herbal medicines are taken by patients for different reasons. Unfortunately, these self-prescribed remedies have many food and drug interactions and unknown adverse effects and can lead to some important consequences. Case presentation: Here a case of bleeding disorder in a 28-year-old woman taking red clover is reported. She had no history of warfarin use, but warfarin was detected in her blood serum analysis. Conclusion: This agent is a source of natural coumarin and can cause an increase of international normalized ratio (INR) and bleeding. It is important that prescribers be alert to the possible disadvantage of herbal remedies and also probable herb-drug and herb-food interactions

Simulation and optimization of electrical discharge machining process using matlab

Electrical discharge machining (EDM) is a nonconventional milling in which holes or shape can be created without any contact between electrode and work piece during the material removal process. Throughout the machining process a series of stochastic sparks are produced when the gap between electrode and work piece is very narrow just about 10 to 50 microns. Controlling this gap in micro dimension not only depends on electrode position but also on work piece surface. So a combination of PID controller and EDM process is used to monitor the gap. In this study an indirect measurement of surface position is carried out by implementing voltage average gap model. And Simulink models have been done to simulate the dynamic behavior of EDM system. Finally Particle Swarm Optimization technique is applied to find optimal performance parameters to have maximum Material Removal Rate