43 research outputs found

    Digital system bus integrity

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    This report summarizes and describes the results of a study of current or emerging multiplex data buses as applicable to digital flight systems, particularly with regard to civil aircraft. Technology for pre-1995 and post-1995 timeframes has been delineated and critiqued relative to the requirements envisioned for those periods. The primary emphasis has been an assured airworthiness of the more prevalent type buses, with attention to attributes such as fault tolerance, environmental susceptibility, and problems under continuing investigation. Additionally, the capacity to certify systems relying on such buses has been addressed

    The disruption of proteostasis in neurodegenerative diseases

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    Cells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome. Disruption of the PN is associated with aging and can lead to and/or potentiate the occurrence of many neurodegenerative diseases (ND). This not only emphasizes the importance of the PN in health span and aging but also how its modulation can be a potential target for intervention and treatment of human diseases.info:eu-repo/semantics/publishedVersio

    Astrionics selection and operation on interplanetary missions

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    A core software concept for integrated control

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    Costs of partner search and selection in strategic alliances

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    This study examines the costs of alliance partner search and selection and their antecedents. Drawing on transaction cost economics and the network perspective on inter-organizational relationships, the findings drawing on survey-based data from a sample of 83 firms in the German telecommunications industry reveal that partner search and selection costs are closely connected but differentially affected by task- and company-related factors. When firms must make alliance-specific investments, search and selection costs increase. A firm’s number of current alliances decreases them, while neither alliance scope nor firm performance significantly affect search and selection costs. Additional analyses show that alliance-specific investments especially increase search costs but do not affect selection costs, while the initiating firm’s performance decreases search costs but it does not reduce selection costs
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