Whey protein consumption after resistance exercise reduces energy intake at a post-exercise meal

Purpose - Protein consumption after resistance exercise potentiates muscle protein synthesis, but its effects on subsequent appetite in this context are unknown. This study examined appetite and energy intake following consumption of protein- and carbohydrate-containing drinks after resistance exercise. Methods - After familiarisation, 15 resistance training males (age 21 ± 1 years, body mass 78.0 ± 11.9 kg, stature 1.78 ± 0.07 m) completed two randomised, double-blind trials, consisting of lower-body resistance exercise, followed by consumption of a whey protein (PRO 23.9 ± 3.6 g protein) or dextrose (CHO 26.5 ± 3.8 g carbohydrate) drink in the 5 min post-exercise. An ad libitum meal was served 60 min later, with subjective appetite measured throughout. Drinks were flavoured and matched for energy content and volume. The PRO drink provided 0.3 g/kg body mass protein. Results - Ad libitum energy intake (PRO 3742 ± 994 kJ; CHO 4172 ± 1132 kJ; P = 0.007) and mean eating rate (PRO 339 ± 102 kJ/min; CHO 405 ± 154 kJ/min; P = 0.009) were lower during PRO. The change in eating rate was associated with the change in energy intake (R = 0.661, P = 0.007). No interaction effects were observed for subjective measures of appetite. The PRO drink was perceived as creamier and thicker, and less pleasant, sweet and refreshing (P < 0.05). Conclusion - These results suggest whey protein consumption after resistance exercise reduces subsequent energy intake, and this might be partially mediated by a reduced eating rate. Whilst this reduced energy intake is unlikely to impair hypertrophy, it may be of value in supporting an energy deficit for weight loss

The Ursinus Weekly, November 13, 1961

J. P. Marquand\u27s Boston satire The Late George Apley Ursinus Curtain Club presentation Friday, Saturday nights: Vee Shibe, Steve Wurster act leads in comedy-drama at T-G Gymnasium • Senator Clark discusses prospects for peace for Ursinus Forum audience Wednesday • Bill Scheuren elected Collegeville J.P. Tuesday • Demas downed in cigarette search by a single soph • U.C. co-ed chosen Miss Liberty Bowl for second year • Dr. Seidel speaks to Beardwood • 625 students state desire to return to mike at meals • Peace Corps man to visit Thursday • Collegeville elects Pancoast mayor; Ursinus prof defeats Democrat 3 to 1 • Bertin outlines seven queries for student teachers • Professors, students start instrumental ensemble • Editorial: Senator\u27s visit; The art of dining • Ursinus in the past • Letters to the editor • Impressions in Moscow • Censor\u27s arm smites Miller\u27s Tropic of Cancer • West Chester snaps hockey streak • JV football initiated here; Help to season the scrubs • Booters tie LaSalle explorers, 1-1, in overtime thriller; Lose to Lehigh • Dutchmen dump Bears, 27-6; Foes\u27 ground game decisive • Ron Ritz\u27s running is bright spot throughout 1961 football season • Greek gleanings • Brodbeck III, day students join Maples, Leber-South in intramural semi-finals • Square Church on campus is Penn minister\u27s topichttps://digitalcommons.ursinus.edu/weekly/1304/thumbnail.jp

Cognitive impairment in sporadic cerebral small vessel disease:A systematic review and meta-analysis

This paper is a proposal for an update on the characterization of cognitive impairments associated with sporadic cerebral small vessel disease (SVD). We pose a series of questions about the nature of SVD-related cognitive impairments and provide answers based on a comprehensive review and meta-analysis of published data from 69 studies. Although SVD is thought primarily to affect executive function and processing speed, we hypothesize that SVD affects all major domains of cognitive ability. We also identify low levels of education as a potentially modifiable risk factor for SVD-related cognitive impairment. Therefore, we propose the use of comprehensive cognitive assessments and the measurement of educational level both in clinics and research settings, and suggest several recommendations for future research

Recent Activities Of The World Data Centre For Geomagnetism (Edinburgh)

For almost 50 years the World Data Centre for Geomagnetism (Edinburgh) has been a custodian of geomagnetic data. In particular, over recent years the scope of the data holdings has been increased, quality control measures introduced and better interfaces to make the data more accessible to users are being developed. The WDC hold geomagnetic time-series data from around 280 observatories worldwide at a number of time resolutions along with various magnetic survey, model, and geomagnetic activity indices. These data are of value to various scientific communities. Commonly the spatial and temporal coverage of geomagnetic observatory data are valuable for geomagnetic field modelling and contribute to models such as the International Geomagnetic Reference Field (Thébault et al., 2015) and the World Magnetic Model (Chulliat et al., 2015). More recently long-time series of geomagnetic data at a higher-cadence (one-minute means) have been useful in the space weather community, for example in extreme event analysis to estimate likely maxima in geomagnetic activity levels (Thomson et al., 2011). Furthermore recent efforts to digitise historic data and magnetograms may help scientists to re-analysis the largest geomagnetic storms of the past such as the 1859 ‘Carrington Event’ (Humphries et al., 2015). The World Data Centre accepts definitive observatory data from all operating observatories who submit their data. The primary aim is to provide a repository of data that is freely accessible to all. That said, good quality science requires good quality data and to that end various quality control checks are applied to on all new data received. Work has also been carried out to assess and improve the quality of our long-standing datasets. Recent activities have focused on the development of an improved user interface in the form of a new Data Portal for geomagnetic observatory data (http://www.wdc.bgs.ac.uk/dataportal/). This sits atop a RESTful web service which should allow other users or data platforms to integrate the data in the WDC more directly into their applications. This and other activities will be presented. We would welcome feedback from the community on these efforts

Whey protein consumption after resistance exercise reduces energy intake at a post-exercise meal

Purpose: Protein consumption after resistance exercise potentiates muscle protein synthesis, but its effects on subsequent appetite in this context are unknown. This study examined appetite and energy intake following consumption of protein- and carbohydrate-containing drinks after resistance exercise. Methods: After familiarisation, 15 resistance training males (age 21 ± 1 years, body mass 78.0 ± 11.9 kg, stature 1.78 ± 0.07 m) completed two randomised, double-blind trials, consisting of lower-body resistance exercise, followed by consumption of a whey protein (PRO 23.9 ± 3.6 g protein) or dextrose (CHO 26.5 ± 3.8 g carbohydrate) drink in the 5 min post-exercise. An ad libitum meal was served 60 min later, with subjective appetite measured throughout. Drinks were flavoured and matched for energy content and volume. The PRO drink provided 0.3 g/kg body mass protein. Results: Ad libitum energy intake (PRO 3742 ± 994 kJ; CHO 4172 ± 1132 kJ; P = 0.007) and mean eating rate (PRO 339 ± 102 kJ/min; CHO 405 ± 154 kJ/min; P = 0.009) were lower during PRO. The change in eating rate was associated with the change in energy intake (R = 0.661, P = 0.007). No interaction effects were observed for subjective measures of appetite. The PRO drink was perceived as creamier and thicker, and less pleasant, sweet and refreshing (P < 0.05). Conclusion: These results suggest whey protein consumption after resistance exercise reduces subsequent energy intake, and this might be partially mediated by a reduced eating rate. Whilst this reduced energy intake is unlikely to impair hypertrophy, it may be of value in supporting an energy deficit for weight loss

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation.

BackgroundMucopolysaccharidosis I (MPS IH) is a lysosomal storage disease treated with hematopoietic cell transplantation (HCT) because it stabilizes cognitive deterioration, but is insufficient to alleviate all somatic manifestations. Intravenous laronidase improves somatic burden in attenuated MPS I. It is unknown whether laronidase can improve somatic disease following HCT in MPS IH. The objective of this study was to evaluate the effects of laronidase on somatic outcomes of patients with MPS IH previously treated with HCT.MethodsThis 2-year open-label pilot study of laronidase included ten patients (age 5-13 years) who were at least 2 years post-HCT and donor engrafted. Outcomes were assessed semi-annually and compared to historic controls.ResultsThe two youngest participants had a statistically significant improvement in growth compared to controls. Development of persistent high-titer anti-drug antibodies (ADA) was associated with poorer 6-min walk test (6MWT) performance; when patients with high ADA titers were excluded, there was a significant improvement in the 6MWT in the remaining seven patients.ConclusionsLaronidase seemed to improve growth in participants &lt;8 years old, and 6MWT performance in participants without ADA. Given the small number of patients treated in this pilot study, additional study is needed before definitive conclusions can be made