Book Review: Introduction to Commercial Transactions (1977)

Book review of INTRODUCTION TO COMMERCIAL TRANSACTIONS, by Robert Braucher & Robert A. Riegert (NY: The Foundation Press, 1977)

Just Sign Here--It\u27s Only a Formality : Parol Evidence in the Law of Commercial Paper

Part I will argue that certainty is especially important in the law of negotiable instruments, although it does not outweigh all other values. In light of the need for certain rules, this Article will consider the policy choices made by the drafters of the Uniform Commercial Code\u27s Article 3 on Commercial Paper with respect to parol evidence. Part II will examine certain parol evidence that is admissible against even the law\u27s most favored plaintiff, the holder in due course. Part III will focus on the Code\u27s indirect treatment of the most troublesome parol evidence problems, those which arise when the holder is not in due course. Part IV will evaluate two examples of explicit statutory rules which prohibit parol evidence

Depletion of Beclin-1 Due to Proteolytic Cleavage by Caspases in the Alzheimer\u27s Disease Brain

The Beclin-1 protein is essential for the initiation of autophagy and recent studies suggest this function may be compromised in Alzheimer’s disease (AD). In addition, in vitro studies have supported a loss of function of Beclin-1 due to proteolytic modification by caspases. In the present study we examined whether caspase-cleavage of Beclin-1 occurs in the AD brain by designing a site-directed caspase-cleavage antibody based upon a known cleavage site within the protein at position D149. We confirmed that Beclin-1 is an excellent substrate for caspase-3 and demonstrate cleavage led to the formation of a 35 kDa C-terminal fragment labeled by our novel antibody following Western blot analysis. Application of this antibody termed Beclin-1 caspase-cleavage product antibody or BeclinCCP in frontal cortex tissue sections revealed strong immunolabeling within astrocytes that localized with plaque-regions and along blood vessels in all AD cases examined. In addition, weaker, more variable BeclinCCP labeling was also observed within neurofibrillary tangles that co-localized with the early tau conformational marker, MC-1 as well as the late tangle marker, PHF-1. Collectively, these data support a depletion of Beclin-1 in AD following caspase-cleavage

Managing Milk Composition: Feed Additives and Production Enhancers

4 pp., 1 table, 1 photoFeed additives play an essential role in enhancing production and yield of milk and milk components. Producers should, however, evaluate the cost-to-benefit ratio of each feed additive in their management systems. This publication explains how to evaluate cost effectiveness

Managing Milk Composition: Maximizing Rumen Function

4 pp., 4 tables, 1 photoFeeding strategies that optimize rumen function also maximize milk production and milk component percentages and yield. This publication offers guidelines for feeding forage, grain protein and ration fiber to enhance rumen function

Managing Milk Composition: Normal Sources of Variation

4 pp., 2 tables, 2 figures, 1 photoMany factors influence the composition of milk, including environment, level of production, stage of lactation, disease, season, and genetics and age of the animal. This publication explains the effect of each

Managing Milk Composition: Evaluating Herd Potential

4 pp., 4 tables, 2 photosBefore trying to alter and improve milk fat and protein production of a dairy herd, it is important to evaluate the herd's potential to respond to feed management changes. This publication offers some key points that can be used to help determine that potential

Biosecurity Practices for Dairy Operations

8 pp., 8 photos, 2 tablesThis publication explains how diseases are transmitted and how dairy producers can establish prevention programs with proper biosecurity practices. Tables list common diseases of dairy cattle and ways they are treated