1 research outputs found
Groin recurrence in patients with early vulvar cancer following superficial inguinal node dissection
AbstractObjectiveTo investigate the causes of groin recurrence in patients with vulval cancer who previously had negative nodes following superficial inguinal node dissection (SIND).Material and methodsForty-one patients with squamous cell carcinoma of the vulva (stage I or II) were operated upon. The primary treatment was wide local excision with 2cm safety margin and superficial inguinal lymphadenectomy. Six patients had ipsilateral and one patient had bilateral groin recurrence. Those patients were subjected to deep inguinal node dissection (one patient required bilateral node dissection).ResultsThe mean age at time of diagnosis was 59years (range 51β68). The median follow-up period for all patients was 63months (range 24β71) and that of the recurrent cases was 20months (range 12β38). The mean depth of invasion of the recurrent cases was 5.5mm (range 5β5.9mm) and the mean diameter of the primary tumor in recurrent cases was 3.8cm (range 3β4.5cm). All recurrent cases had a high grade of the primary tumor. The median interval to recurrence was 21months (range 12β57). The groin recurrence rate after negative SIND was 17% (7/41 patients).The mean number of nodes resected per groin was eight (range 1β17). The nodes ranged in size from 0.2 to 4.0cm.ConclusionCarcinoma of the vulva with the following criteria (size of tumor is greater than 3cm, depth of invasion greater than 5mm, and high grade tumors) is at high risk of recurrence