Objectives:. To comprehensively classify interventions performed by emergency medicine clinical pharmacists and quantify cost avoidance generated through their accepted interventions.
Design:. A multicenter, prospective, observational study was performed between August 2018 and January 2019.
Setting:. Community and academic hospitals in the United States.
Participants:. Emergency medicine clinical pharmacists.
Interventions:. Recommendations classified into one of 38 intervention categories associated with cost avoidance.
Measurements and Main Results:. Eighty-eight emergency medicine pharmacists at 49 centers performed 13,984 interventions during 917 shifts that were accepted on 8,602 patients and generated 7,531,862ofcostavoidance.Thequantityofacceptedinterventionsandcostavoidancegeneratedinsixestablishedcategorieswereasfollows:adversedrugeventprevention(1,631interventions;2,225,049 cost avoidance), resource utilization (628; 310,582),individualizationofpatientcare(6,122;1,787,170), prophylaxis (24; 22,804),handsβoncare(3,533;2,836,811), and administrative/supportive tasks (2,046; 342,881).Meancostavoidancewas538.61 per intervention, 875.60perpatient,and8,213.59 per emergency medicine pharmacist shift. The annualized cost avoidance from an emergency medicine pharmacist was 1,971,262.Themonetarycostavoidancetopharmacistsalaryratiowasbetween1.4:1 and 10.6:1.Conclusions:.Pharmacistinvolvementinthecareofpatientspresentingtotheemergencydepartmentresultsinsignificantavoidanceofhealthcarecosts,particularlyintheareasofhandsβoncareandadversedrugeventprevention.Thepotentialmonetarybenefitβtoβcostratioforemergencymedicinepharmacistsisbetween1.4:1 and $10.6:1