Ethical Problems in Evaluation Research

For some time, social scientists have been concerned with ethics in research. Much of what they have written has focused on research in general, but many of the points they raise are applicable to evaluation research in particular. Included among these concerns are informed consent, the right to treatment, the right to refuse treatment, implicit coercion, powerlessness of subjects, and, perhaps most important, external access to confidential data

Activity of Exoenzymes in Treated Wastewater Irrigated Soils

The reuse of reclaimed wastewater for irrigation of agricultural fields greatly influences the activity of soil microorganisms through the input of organic compounds. Due to the production of exoenzymes by microorganisms for the decomposition of substrates it can be assumed that the irrigation with treated wastewater (TWW) has a strong influence on the soil enzyme pool. In this study the activity of ten exoenzymes, which catalyses processes in C, N and P nutrient cycles, were determined in 3 different soils in 0-10, 10-20, 20-30, 30-50, 50-70 and 70-100 cm soil depth. The soils were used for agriculture and irrigated with reclaimed wastewater reused after a secondary treatment step. Additionally a control after freshwater irrigation was studied. Due to the influence of TWW on the soil biology of these soils, also clear effects on soil exoenzymes in freshwater and TWW irrigated soils could be seen. According to Sinsabaugh et al. (2008) we calculated indices which describe the enzymatic resources for acquisition of organic P and organic N relative to C and therefore give insides into the functional convergence of extracellular enzyme activities in soils and the relative nutrient demand. The distribution pattern of these functional enzyme activities varied between freshwater and TWW irrigated soils and shows therefore a strong influence of the TWW irrigation on the activity of exoenzymes. (Sinsabaugh et al. (2008): Stoichiometry of soil enzyme activity at global scale. Ecology Letters 11 (11), 1252-1264.

Migration, Remittances and Gender-Responsive Local Development: Executive Summaries. Case Studies: Albania, the Dominican Republic, Lesotho, Morocco, the Philippines and Senegal

The complex links between globalization and development have made contemporary migration a key area of investigation. It is estimated that over 200 million women and men have left their countries of origin to live and work abroad. Occurring simultaneously are equally intensive internal movements, primarily from rural to urban areas. Demographically, many country-specific flows have changed, both in terms of numbers and composition by sex. Studies on the feminization of migration2 have revealed women’s significant role and impact as actors in the migration process. Despite the rapid increase in the volume and diversity of knowledge on the migration-development nexus, research and debate on the gender dimensions of this issue, including the role of women within migratory flows, continues to be scarce. In 2007, the United Nations Development Programme (UNDP) and the United Nations International Research and Training Institute for the Advancement of Women (UN-INSTRAW) began a joint project entitled “Gender and Remittances: Building Gender-Responsive Local Development. ” The project has sought to enhance gender-responsive local development by identifying and promoting options for utilizing remittances for sustainable livelihoods and for building social capital in poor rural and semi-urban communities. The research phase of the project has been implemented in six countries: Albania, the Dominican Republic, Lesotho, Morocco, the Philippines and Senegal. The strategic aim of the project is to generate action-oriented research that will be used to: Increase awareness and improve access of women-headed, remittance-recipient households to productive resources, while augmenting their assets and strengthening their capacities; Provide relevant information to local and national governments to identify and formulate policies that will optimize remittance utilization for sustainable livelihoods and for building social capital; and Contribute to enhancing key stakeholders’ capacities to integrate gender into policies, programmes, projects, and other initiatives linking remittances with sustainable livelihoods and building social capital. The six case studies aim to narrow the knowledge gap on the gender dimensions of migration and remittances through an interlinked analysis of migration and development. Particular attention is paid to the impact of remittances (financial, in-kind and social) on gendered development processes in countries of origin and amongst transnational households spanning the origin and destination countries

Confidence regions for means of multivariate normal distributions and a non-symmetric correlation inequality for gaussian measure

Let $\mu$ be a Gaussian measure (say, on ${\bf R}^n$) and let $K, L \subset {\bf R}^n$ be such that K is convex, $L$ is a "layer" (i.e. $L = \{x : a \leq < x,u > \leq b \}$ for some $a$, $b \in {\bf R}$ and $u \in {\bf R}^n$) and the centers of mass (with respect to $\mu$) of $K$ and $L$ coincide. Then $\mu(K \cap L) \geq \mu(K) \cdot \mu(L)$. This is motivated by the well-known "positive correlation conjecture" for symmetric sets and a related inequality of Sidak concerning confidence regions for means of multivariate normal distributions. The proof uses an apparently hitherto unknown estimate for the (standard) Gaussian cumulative distribution function: $\Phi (x) > 1 - \frac{(8/\pi)^{{1/2}}}{3x + (x^2 +8)^{{1/2}}} e^{-x^2/2}$ (valid for $x > -1$)

Rat Monoclonal Antibodies Specific for LST1 Proteins

The LST1 gene is located in the human MHC class III region and encodes transmembrane and soluble isoforms that have been suggested to play a role in the regulation of the immune response and are associated with inflammatory diseases such as rheumatoid arthritis. Here we describe the generation and characterization of the first monoclonal antibodies against LST1. Two hybridoma lines secreting monoclonal antibodies designated 7E2 and 8D12 were established. The 7E2 antibody detects recombinant and endogenous LST1 by Western blot analysis while 8D12 reacts with recombinant and endogenous LST1 in immunoprecipitation and flow cytometry procedures. The newly established antibodies were used to survey LST1 protein expression in human cell lines, which was found to be tightly regulated, allowing the expression of transmembrane isoforms but suppressing soluble isoforms