1,048 research outputs found
Implementation and Results of a New Problem Solving Approach in Physics Teaching
Teaching problem solving is one of the most important topics of physics education while students have big troubles with physics problem solving. The aim of this research is to investigate the impact of extended problem-solving strategy instruction on the development of pre-service science teacher’s problem-solving, critical thinking, metacognitive awareness, and logical reasoning skills. Extended Problem-Solving Strategy has been developed for university physics courses by researcher. This strategy has importantance in terms of covering many previous strategies in physics education literature and including many new steps. The model of the research consisted of an experimental design with pre-test and post-test control groups. Pre-services randomly assigned to the experimental (N=30) and control groups (N=30). The results of the research indicate that the post scores of the experimental group students significantly higher than control group students after the implementations in terms of metacognitive awareness, critical thinking, problem solving and logical thinking skills.This research revealed the positive effects of the “Extended Problem-Solving Strategy” implementation in the physics course at the university level on the skills which are listed among the 21st Century skills and each of these skills affects the other skills positivel
The social and science teacher candidates’ creativity on material using and designing
AbstractThe purpose of this research is to determine the creativity on material design of science and social teacher candidates. For this purpose, 38 students were selected from science and 39 students were selected from social teacher candidates from a government university in Istanbul. This work is a case study. As a means of data collection by researchers, developed by taking 3 experts opinion polls are used. Pilot studies before application of principles of survey can be done is not obvious statements were corrected and brought to final form questionnaire. Data tables using percentage and frequency and content analysis were evaluated
İlköğretim Okullarında Görev Yapan Öğretmenlerin Bireyselleştirilmiş Eğitim Programının Uygulanmasına İlişkin Öğretmen Görüşleri
Bu araştırmada, ilköğretim okullarında görev yapan öğretmenlerin bireyselleştirilmiş eğitim programının (BEP) uygulanmasına ilişkin öğretmen görüşlerini belirlemek amaçlanmıştır. 2017-2018 eğitim öğretim yılında Zonguldak İli Devrek İlçesinde gerçekleştirilen çalışma kapsamında farklı okul ve branşlarda görev yapan 12 öğretmen ile görüşmeler yapılmıştır. Nitel olarak şekillenen araştırmanın verilerinin toplanmasında araştırmacı tarafından geliştirilen görüşme formu kullanılmıştır. Görüşme soruları belirlenirken önce alanyazın taranmıştır. Yapılan araştırmalardan sonra taslak maddeler oluşturulmuştur. Görüşme formuna son halini vermeden önce 6 uzman görüşünden yararlanılmıştır. Ses kaydına alınarak gerçekleştirilen görüşmelerin süresi 15-20 dakikadır. Veriler içerik analizi kullanılarak çözümlenmiştir. Araştırma sonucunda öğretmenlerin, kaynaştırma uygulaması ve BEP uygulama sürecine yönelik olarak süre sıkıntısı, velilerin bilinçsiz olması, uygulamada yaşanan aksaklıklar, verilen hizmet içi eğitim ve seminerlerin yetersiz olması, bilgi eksikliği, rapor verilme aşamasında yaşanan sıkıntılar gibi çeşitli sorunlarla karşılaştıkları görülmüştür. Öğretmenler, kaynaştırma eğitiminin mevcut haliyle faydalı olduğunu düşünmemektedir. Eğitimlerin yeterli hale getirilmesi, destek odalarının her okulda bulunması, okul ve aile iş birliğinin kuvvetlendirilmesi öğretmenlerin ifade ettiği çözüm önerileri arasındadır
Realistic simulations of the AGATA Demonstrator+PRISMA spectrometer
Abstract The performance of the AGATA Demonstrator Array coupled to the PRISMA magnetic spectrometer has been evaluated consistently by using detailed Monte Carlo simulations of the two devices. Results for the multi-nucleon transfer reaction 48Ca+208Pb at 310 MeV beam energy are presented and discussed in this study. The present results suggest that the Doppler correction capabilities of the AGATA+PRISMA setup will be very close to the intrinsic energy resolution of the germanium detectors
Effect of binge eating disorder on the treatment process of bariatric surgery
Geçmişten günümüze yaygınlığı hızla devam eden obezite, fiziksel, sosyal, çevresel ve psikolojik etkileri olan bir hastalıktır. Obezitenin birçok sebebinin olması ve eşlik eden hastalıkların bulunması, tanı alma ve tedavi sürecinde ciddi sonuçlarla karşılaşılmasına yol açmaktadır. Obezite tedavisi için seçilen yöntem kişinin beden kitle indeksine ve eşlik eden hastalığın varlığına göre değişiklik göstermektedir. Bu yöntemlerden biri olan, bariatrik ve metabolik cerrahi (obezite cerrahisi) kişinin obezitesine ek olarak sahip olduğu diğer hastalıklara ve cerrahın tercihine göre uygulanmaktadır. Bu konuda bilinmesi gereken en önemli şey; obezite cerrahisinin kapsamlı bir tedaviyi gerektirdiği ve tedavi sürecinin bir ekip ile birlikte yürütülmesi gerektiğidir. Cerrahi operasyon sonrası kişi iç hastalıkları uzmanı, obezite cerrahisi alanında uzmanlaşmış diyetisyen, beslenme ve yeme bozuklukları alanında uzmanlaşmış bir psikiyatrist ya da psikolog tarafından multidisipliner bir yaklaşım ile takip edilmelidir. Operasyon öncesi ve sonrası karşılaşılan, operasyonun başarısını olumsuz yönde etkileyebilen, en önemli sorunlardan biri ise tıkınırcasına yeme bozukluğudur. Bu makalede, tıkınırcasına yeme bozukluğu ve ruhsal durumun obezite cerrahisini nasıl etkilediği üzerinde durulmuştur.Obesity, which continues to be widespread from past to present, is a disease to have physical, social, environmental and psychological effects. The presence of many causes of obesity and its comorbid diseases results in serious financial consequences in the diagnostic and treatment process. The methods chosen for the treatment of obesity varies according to the person's body mass index and the presence of comorbid disease. One these methods is bariatric and metabolic surgery (obesity surgery), and it isapplied in the case of having additional diseases to patient’s obesity and preferences of surgeon in addition to obesity. The most important thing to know about this issue is that obesity surgery is involved in a very comprehensive treatment. After surgery, the person should be followed with a multidisciplinary approach by an internal medicine specialist, a dietician specializing in bariatric surgery, a psychiatrist or psychologist specializing in nutrition and eating disorders. One of the most important problems encountered before and after the operation, which may adversely affect the success of the operation, is binge eating disorder. This article focuses on how binge eating disorder and mood influence obesity surgery.Publisher's Versio
The effect of femoral nerve block on fracture healing via expressions of growth factors and β-catenin
Introduction. Many patients of all ages are admitted to hospital due to bone fractures. The etiology of fracture has a very wide spectrum, ranging from motor accidents to pathological conditions such as tumors, osteoporosis, and others. Bone fracture healing is a well-programmed and well-organized process, but is also long and intractable. The outcome of this process is therefore affected by many factors, such as the patient’s age, ethnicity, nutritional status, and extent of the fracture. At present, regional analgesic techniques are frequently applied in order to avoid the complications of systemic opioid administration, central block applications. Femoral block is one of the regional analgesic techniques frequently applied by anesthesiologists when the lower extremities are involved. In this study, we evaluated the effect of femoral nerve block on the healing of an experimental non-stabilized femur fracture via expression of TGF-β, VEGF, and β-catenin and bone histomorphometry in rats.
Material and methods. In the control group, only the femoral fracture was performed and the bone was not fixated, similarly as in other groups. In the One-Day Block group, a one-time femoral nerve block was applied after the femoral fracture. In the Three-Day Block group, a daily femoral nerve block was performed for three days after the femoral fracture. On Days 4, 7, and 13, femurs were excised. The bone sections were stained with hematoxylin-eosin to evaluate bone tissue and Safranin O to assess callus tissue, cartilaginous tissue, and new bone areas. TGF-β, VEGF, and β-catenin were assessed by immunohistochemistry.
Results. Histomorphometric analysis revealed that femoral block application had a positive impact on bone healing. TGF-β expression in the One-Day and Three-Day Block Groups was significantly higher than in the control group at all times, as was also the case with VEGF expression. On day 13, β-catenin expression was significantly higher in the Three-Day Block group than the others.
Conclusions. The results of the study suggests that the applications of a femoral nerve block for perioperative analgesia, for either one day or three days, resulted in better and more rapid bone healing
Assessment of the marginal microleakage of flowable composites in class V cavities prepared by Er:YAG laser and high-speed bur
Amaç: Bu çalışmanın amacı, Er:YAG lazer ya da yüksek hızlı döner aletler ile kavite hazırlığı yapılan ve üç farklı akışkan kompozit materyali kullanılarak gerçekleştirilen sınıf V restorasyonlarda kenar mikrosızıntılarının incelenmesidir. Gereç ve Yöntem: Bu in-vitro çalışmada, toplam 33 adet üçüncü büyük azı dişlerinin bukkal ve lingual yüzeylerinde Er:YAG lazer ya da frez kullanılarak sınıf V kaviteler hazırlanan örnekler altı gruba (n=11) ayrıldı ve üretici firmanın talimatlarına uygun olarak üç farklı akışkan kompozit ile restore edildi. Grup 1: Lazer ile hazırlık (lh)+Estelite Flow Quick High flow (EF); Grup 2: lh+G-aenial Flo (GF); Grup 3: lp+Herculite XRV Ultra Akış (HF); Grup 4: Frez ile hazırlık (fh)+EF; Grup 5: fh+GF; Grup 6: fh+HF. Isısal çevrim uygulanmasının ardından örnekler %0,5 metilen mavisi solüsyonunda 24 saat süresince bekletildi. Boya penetrasyonu sonucu oluşan mikrosızıntı, stereomikroskop altında x40 büyütme ile incelendi. Verilerin analizinde Kruskal Wallis ve Mann-Whitney U testleri kullanıldı (p0.05). In terms of gingival and occlusal surfaces, no statistically significant difference in microleakage was observed among all groups (p>0.05). Conclusion: Class V cavity preparations with high-speed bur and Er:YAG laser, and the use of different flowable composites did not influence the microleakage at the gingival or occlusal margins
Behaviour of 9-Ethyl-9H-carbazole Hydrazone Derivatives Against Oxidant Systems: Protective Effect on Amyloid β-Induced Damage
Antioxidants are helpful in prevention of several diseases related with oxidative stress including neurodegenerative disorders. In recent studies, carbazoles were given proof of promising antioxidant activities. In this article, 9-ethyl-9H-carbazole hydrazone derivatives were synthesized, characterized and their in vitro antioxidant activity and possible cytotoxic effects were investigated. Furthermore, protective effect of the synthesized derivatives against amyloid β-induced damage in PC12 neuronal cells was examined by using MTT assay. The newly synthesized carbazoles were found to have radical scavenging activity with a varying potency both in cell-free and cell-based in vitro assays. Several compounds, especially such as 3d and 3e, 3m and 3n bearing two halogen groups on the phenyl ring, were found to have cytotoxic activity. However, their cytotoxic activities were not higher than that of melatonin. Several compounds also significantly protected neuronal PC12 cells against amyloid β-induced damage, which can be defined as neuroprotective agents. (4-(2-((9-Ethyl-9H-carbazol-3-yl)methylene)hydrazinyl)benzonitrile) 3r was found as the most active compound with both radical scavenging activity and neuroprotective effects against amyloid β-induced damage. These findings might provide an alternative strategy for developing novel carbazole derivatives for management of neurodegenerative diseases, such as Alzheimer\u27s disease.
This work is licensed under a Creative Commons Attribution 4.0 International License
Multipl miyelom tanılı hastalarda EORTC QLQ ile yaşam kalitesi değerlendirmesi: Çok merkezli çalışma
Objective: Both the length of the treatment period and the diversity of the agents used in the treatment significantly affect the quality of life (QoL) of the patients with multiple myeloma (MM). With the aid of the EORTC Quality of Life Questionnaire Consisting of 30 Questions “EORTC QLQ-C30” and the Quality of Life Questionnaire Multiple Myeloma Module “QLQ-MY20”, we aimed to obtain data on quality of life in MM patients in a representative sample of the general population of our country. Methods: One hundred sixty eight patients from 6 different centers followed between 2018-2020 were included in the study. The QLQ-C30, and the QLQ-MY20 questionnaires specific for MM patients were used and the results were reported statistically. Results: Seventy eight (46%) of the patients were female, while 90 (54%) were male. The median age was 64 (22-84). When the findings were analysed, it was found that there was a greater effect on the symptom scale compared to the functional scale. Conclusion: The importance of the treatment-related side effect management, together with the adequate administration of appropriate symptomatic treatment in holistic treatment management were emphasized as effective factors in terms of the QoL of patients with MM.Amaç: Hem tedavi süresinin uzunluğu, hem de tedavide kullanılan ajanların çeşitliliği multipl miyelomlu (MM) hastaların yaşam kalitesini (YK) önemli ölçüde etkiler. Otuz sorudan oluşan EORTC Yaşam Kalitesi Anketi “EORTC QLQ-C30” ve Yaşam Kalitesi Anketi-Multipl Miyelom Modülü “QLQ-MY20” yardımıyla MM hastalarında yaşam kalitesine ilişkin verileri elde etmeyi amaçladık. Yöntem: 2018-2020 yılları arasında takip edilen, 6 farklı merkezden 168 hasta çalışmaya dahil edildi. MM hastalarına özel QLQ-C30 ve QLQ-MY20 anketleri kullanılmış ve sonuçlar istatistiksel olarak rapor edilmiştir. Bulgular: Hastaların 78’i (%46) kadın, 90’ı (%54) erkekti. Ortanca yaş 64 (22-84) idi. Bulgular incelendiğinde semptom ölçeğinde fonksiyonel ölçeğe göre daha fazla etkinin olduğu görüldü. Sonuç: Bütüncül tedavi yönetiminde, uygun tedavinin yeterli uygulanması ile birlikte tedaviye bağlı yan etki yönetiminin önemi, MM’li hastaların yaşam kalitesi açısından etkili faktörler olarak vurgulanmıştır
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