The Unstable Narrative: an Explication of Ambiguity in Works by Henry James, Thomas Mann, and Richard Wright

Explication of ambiguity in the narration of Henry James\u27s The Bostonians, Thomas Mann\u27s Death in Venice, and Richard Wright\u27s Native Son

Supplementary Figure 6 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 6 shows the phenotype of B16-OVA tumor infiltrating Phgdh deficient OT-1 cells.</p

Supplementary Figure 3 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 3 shows the cytotoxicity of previously activated CD8+ T cells with or without the SHMT inhibitor.</p

Supplementary Figure 7 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 7 shows individual mouse growth curves from those depicted in main Figure 4.</p

Supplementary Figure 8 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 8 shows a diagram of the CD8 depletion strategy and individual growth curves from CD8 depleted mice in main Figure 4.</p

Supplementary Figure 9 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 9 shows tumor impacts of formate on and/or anti-PD-1 treatment on EO771 and 4T1 tumor growth & animal survival.</p

Supplementary Figure 5 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 5 shows Chimeric IMmune Editing (CHIME) can disrupt Phgdh causing loss of PHGDH expression and serine biosynthesis in CD8+ T cells.</p

Supplementary Figure 4 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 4 shows metabolite concentrations in the plasma and tumor interstitial fluid of B16-OVA tumor bearing mice.</p

Supplementary Figure 11 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 11 shows single cell RNA sequencing analysis for tumor infiltrating CD8+ T cells following formate and/or anti-PD-1 antibody treatment.</p

Supplementary Figure 10 from Formate Supplementation Enhances Antitumor CD8⁺ T-cell Fitness and Efficacy of PD-1 Blockade

Supplementary Figure 10 shows individual mouse growth curves from those depicted in main Figure 4.</p