Hémorragie digestive haute suite à une tumeur stromale gastro-intestinale : à propos d’un cas: Upper digestive hemorrhage following a gastrointestinal stromal tumor: a case report

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors that can be life-threatening. Acute gastrointestinal bleeding requiring urgent surgery may occur in small percentage of GIST. Here, we describe a case of giant GIST of the stomach complicated by digestive hemorrhages treated in emergency by surgical resection consisting of an atypical type of gastrectomy taking away the tumor. Les tumeurs stromales gastro-intestinales (GIST) sont les tumeurs mésenchymateuses les plus courantes, sombrant parfois le pronostic vital. Des hémorragies gastro-intestinales aigues nécessitant une intervention chirurgicale urgente surviennent dans une petite fraction. Ici, nous décrivons un cas d’une GIST géante de l’estomac compliquée d’hémorragies digestives traité par résection chirurgicale, en urgence, à type de gastrectomie atypique emportant la tumeur. &nbsp

Intrarectal Migration of an Intrauterine Device: A Case Study and Review of Literature

Intrauterine devices (IUDs) are a widely used and generally safe method of long-term contraception. However, complications such as uterine perforation and migration can occur, although they are rare. This article presents a case of a 30-year-old woman with a history of two pregnancies and deliveries, who had a copper IUD inserted two years prior during the lactation period. She was admitted with severe pelvic pain and constipation lasting for three days, without externalized gastrointestinal bleeding or vomiting. Clinical examination revealed generalized abdominal tenderness with hypogastric guarding, while laboratory tests indicated elevated inflammatory markers. Imaging studies, including abdominal ultrasound and CT scan, revealed the migration of the IUD and its partial perforation into the rectal ampulla. Emergency surgery was performed, including the repair of a rectal perforation, lateral protective colostomy, and appendectomy. The postoperative course was uneventful, and colonic continuity was restored six weeks later. This case underscores the importance of considering IUD migration in a patients presenting with abdominal pain and highlights the need for timely diagnosis and intervention to prevent serious complications. Regular follow-up and patient education on the potential risks and signs of IUD complications are essential for early detection and management

Les invaginations intestinales chez l’adulte: à propos de 17 cas

L'invagination intestinale est une affection rare chez l’adulte. Elle conduit le plus souvent à la découverte d’une cause organique pouvant être tumorale. Le but de notre travail est de dégager les particularités épidémiologiques diagnostiques et thérapeutiques de cette affection; à travers une étude descriptive rétrospective, ayant portée sur 17 cas d'invagination intestinale de l'adulte opérés dans le service des Urgences Chirurgicales Viscérales du CHU Ibn Rochd de Casablanca du 1er janvier 2006 au 31 décembre 2010. La douleur abdominale était présente chez tout les patients; L'échographie abdominale pratiquée chez 12 patients; elle a montré une image en cocarde dans 9 cas, une masse abdominale dans 1 cas et un épaississement grèlique dans 5 cas. La tomodensitométrie abdominale faite chez 15 patients a objectivé l’invagination intestinale dans tous les cas. Le traitement chirurgical a été adopté chez tous les patients; il a permis de faire la résection des segments intestinaux invaginé dans tout les cas. Le résultat anatomopathologique de la pièce de résection a retrouvé une cause organique de l’invagination dans dix cas (58,8%). L’invagination intestinale chez l’adulte est souvent secondaire à une lésion organique : tumorale ou inflammatoire. Elle se caractérise par son polymorphisme clinique. Il s’agit essentiellement de phénomènes subocclusifs à répétition. Concernant le traitement de l’invagination intestinale de l’adulte, la résection du segment invaginé est toujours nécessaire car dans 80% des cas, cette affection est secondaire à une lésion organique qui doit être traitée.Pan African Medical Journal 2012; 12:1

Total rupture of hydatid cyst of liver in to common bile duct: a case report

Rupture of hydatid liver cyst into biliary tree is frequent complications that involvethe common hepatic duct, lobar biliary branches, the small intrahepatic bile ducts,but rarely rupture into common bile duct. The rupture of hydatid cyst is serious life threating event. The authors are reporting a case of total rupture of hydatid cyst of liver into common bile duct. A 50-year-old male patient who presented with acute cholangitis was diagnosed as a case of totally rupture of hydatid cyst on Abdominal CT Scan. Rupture of hydatid cyst of liver into common bile duct and the gallbladder was confirmed on surgery. Treated by cholecystectomy and T-tube drainage of Common bileduct. Key words: hydatid liver cyst, Rupture, Common bile duct (CBD),jaundice

Hernie diaphragmatique post traumatique compliquée d’un volvulus gastrique : à propos d’un cas : Post-traumatic diaphragmatic hernia complicated by gastric volvulus: a case report

Diaphragmatic rupture following a closed abdominal thoraco-trauma is often not immediately recognized and can be revealed by a strangulation of a neighbouring organ, particularly the stomach. We reported herein the case of a young patient with a history of a violent closed thoracoabdominal trauma that occured two years before his admission to the emergency Unit with a respiratory distress. The diagnosis is only based on thoracoabdominal CT and the treatment is essentially surgical. Mortality remains high, hence the interest in suspecting diaphragmatic rupture in any violent thoraco-abdominal trauma. La rupture diaphragmatique suite à un traumatisme thoraco abdominale fermé est souvent méconnue après l’accident et peut être révélée par un étranglement d’un organe de voisinage notamment l’estomac. Nous rapportons le cas d’un jeune patient ayant comme antécédent un traumatisme thoraco-abdominal fermé violent survenu deux ans avant son admission aux urgences. Il fut admis dans un tableau de détresse respiratoire. Le diagnostic repose uniquement sur la TDM thoraco abdominale et le traitement était essentiellement chirurgical. La mortalité reste élevée d’où l’intérêt de suspecter une rupture diaphragmatique chez tout traumatisme thoraco abdominal violant

Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) and its receptor PROKR2 are associated to human colorectal cancer progression and peritoneal carcinomatosis

International audienceBACKGROUND:The highest risk factor for mortality among malignant tumors is metastasis. Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) is an angiogenic factor which biological activity is mediated via two G protein-coupled receptors, prokineticin receptor1 (PROKR1) and PROKR2. Recent studies suggested that EG-VEGF expression is deregulated in multiple cancers including colorectal cancer (CRC).METHODS:Using distinctive CRC and peritoneal carcinomatosis (PC) cohorts and corresponding control cohort, we determined the circulating levels of EG-VEGF and its in situ expression, and that of its related receptors.RESULTS:Circulating EG-VEGF levels were significantly increased in patients with metastatic PC compared to CRC and control patients (p< 0.05). Furthermore, according to clinicopathologic examinations, local EG-VEGF expression correlated with higher tumor and nodal stages (p< 0.001) of CRC. EG-VEGF and PROKR2 were highly expressed in colorectal primary lesions compared to positive controls. PROKR1 expression was lower and did not change in tumor specimens. Also, EG-VEGF and its receptor PROKR2 were differentially expressed in the colorectal primary lesions and in the control groups.CONCLUSION:Altogether these findings suggest that EG-VEGF/receptors system might be an important actor in the CRC progression into PC and might be involved in the ability of tumor cells to invade other organs. Circulating EG-VEGF could be proposed as a prognostic marker in human CRC and its progression into PC