Diagnosis of exclusion in Burning Mouth Syndrome (BMS)

Internationally, relatively few studies have been undertaken regarding research on non-specific oral burning pain, especially regarding the identification of possible causal factors. Knowledge in this field from a physiopathological and therapeutic perspective is recent, which supports the need for further study and the definition of the disease as an interdisciplinary syndrome. Deepening the research on the etiopathogenesis of burning mouth syndrome (BMS) would be beneficial to medical practice, as it would allow for appropriate therapy and an increased healing rate

Burning mouth syndrome (BMS) - possible pathogenesis related to pain pathways

Burning mouth syndrome (BMS) has been admitted relatively recently as a condition/syndrome within oral pathology, bordering various other medical specialties, which may collaborate to determine the diagnosis and especially to achieve therapeutic success. From a clinical point of view, BMS can present itself in 2 forms: the primary/essential form, whose etiopathogenesis is unexplained, justifying the permanent concern as a topic of research at the international level, and the secondary form, in which the causes of the syndrome can be identified and treated/ removed, allowing healing. Particular to the primary form of BMS is the discrepancy between the extent of subjective pain felt by the patient as “burning” and the lack of any objective (clinical) signs in the oral mucosa. In this form of BMS, the pathogenesis of pain can be explained by invoking the role and importance of the field and some favorable factors. In recent years it has been noticed that changes in taste perception and pain tolerance could be possible causes of the “burning” sensation. Thus, the involvement of the field allowed the following hypothesis to be issued, namely that taste is generated mainly at the level of the fungiform lingual papillae

Myeloperoxidase (MPO) – possible diagnosis biomarker and risk stratification in myocardial inotropism deficit induced by chronic ischemic heart disease

The myeloperoxidase levels of 208 patients with ischemic heart disease hospitalized for congestive heart failure were tested at admission, and discharge after 14 days. The calculations for the serum average concentration/lot/date, were made, subsequent, using the values of the tested parameters regarding MPO (admission and discharge) the mean concentration/lot was made, regardless of time of determination. The calculated average values analyses of the three MPO serum parameters were constantly elevated and permanently matched the myocardial contractility deficiency class. The integrated data of the study, allows us to propose the MPO’s circulating concentration as a diagnosis and risk assessment biomarker in the etiology of myocardial ischemia for chronic cardiac failure

Evaluation of microbial contamination in a surgical department of a Romanian military emergency hospital - A case study

Assessment of the microbial load of the operating environment during daily pre-, intra-, and post-operative procedures in a surgical department of a military emergency hospital in Bucharest showed the bacterial contamination of intra-operative air by increasing the number of bacteria above the allowed maximum level and the detection of a strain of Escherichia coli (E. coli)

CLINICAL ASPECTS OF THE ORAL MUCOSA IN PATIENTS WITH SLEEP-OCCURRING BRUXISM

Aim of the study The objective of this study is represented by the identification of the clinical aspects of the oral mucosa in patients with bruxism occurring during sleep. Material and methods. The study group was represented by a number of 70 patients, women and men. The oral examinations were performed on a number of 51 patients who self-reported bruxism during sleep at the Oral Rehabilitation Clinic of the Faculty of Dentistry, “Ovidius” University in Constanța between January 2018 and January 2019. The collected data have were analyzed using the MICROSOFT-EXCEL program. Results. A number of 127 modifications in the oral mucosa were analyzed. The most frequent modifications were in the following regions: jugal mucosa (24%), inferior buccal alveolar mucosa (17%), superior buccal alveolar mucosa (10%), the dorsal surface of the tongue (10%). The presence of linea alba was observed in 51% of patients. The presence of geographic tongue (11.8%) and the presence of dental impressions (10.7%) was also observed. Conclusions. Oral mucosal modifications in patients with self-reported sleep bruxism are frequently found at the level of the jugal mucosa, inferior alveolar vestibular mucosa, superior alveolar vestibular mucosa and the dorsal surface of the tongue. Some of these modifications are manifestations in the context of bruxism, others have not been associated with bruxism until now

PRELIMINARY STUDY ON THE DISTRIBUTION OF PARTIAL EDENTATIONS IN A BATCH OF YOUNG ADULTS

Objective. The purpose of the study was to analyze the distribution of partial edentation in the young adult. Material and method. The study was conducted on a batch of young adult patients examined between 2015- 2016. Their social and demographic data odontal status were recorded for each patient. The criterion of inclusion in the study was the presence of at least one edentation. The data obtained were statistically processed in SPSS 13.0 for Windows. Results. Out of the 162 patients between 18 and 35 years of age (average age 27.01 +/- 5.09 years, the 21-22 years of age group being best represented), 147 (70 male and 77 female) showed at least one edentation. The average number of edentations per patient was 2.17 (2.03 for female patients and 2.31 for males). Most edentate breaches were of one tooth. According to Kennedy classification, most edentations were class III, followed in decrease order by class I, II and IV. There was no statistically significant difference between the presence of the edentation and the patient's gender (p = 0.788), the origin environment (p = 0.825) or the education level (p = 0.577). In 116 (78.91%) cases, decay was the main cause of edentation. Conclusions. Approximately 91% of young adults showed at least one partial edentation, the most frequent form being Kennedy III class. The high prevalence of partial edentations among young adults emphasizes the importance and the need of enforcing preventative methods or decay treatment in their early stages

Adiponectin – stratification biomarker in diastolic cardiac dysfunction

AbstractThis study does not propose to elucidate how adiponectin secretion is regulated, but how its adiponectin concentration is an indicator of heart disease. About adiponectin, it is not known whether it is functionally an enzyme, or very likely a cytokine/chemokine/hormone, secreted by fat cells/adipocytes in the abdomen. Abdominal fat secretes 67 hormones, and all of which cause disease. For example, adiponectin generates diabetes and ischaemic heart disease via dyslipidemia. Based on clinical symptoms, electrocardiographic and echocardiographic parameters, a group of 208 patients with diastolic cardiac dysfunction with or without preserved systolic function, developed on a background of painful chronic ischaemic heart disease, stable angina on exertion, was constituted. The serum levels of adiponectin, total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides were measured. Using the identified values, it was appreciated whether adiponectin correlates with the type of any of the two conditions, so that it can be recognised as a diagnostic and risk stratification marker

THE REHABILITATION OF ANTHROPOLOGICAL PARAMETERS THROUGH BONE REGENERATION MATERIALS AND TECHNIQUES

Bone regeneration materials and techniques aid in restoring bone structure and function, consequently improving mobility and alleviating discomfort or disability in individuals suffering from bone defects or injuries. This restoration contributes significantly to an improved quality of life for affected individuals. Continuous research and innovation in bone regeneration materials have led to the development of more sophisticated and effective techniques. These advancements are pivotal in the evolution of medical technology and its potential to address various bone-related conditions. Traditional methods, such as autografts, are associated with limitations like donor site morbidity and limited supply. Emerging bone regeneration materials and techniques offer alternatives that mitigate these issues, potentially reducing reliance on traditional approaches. In conclusion, the utilization of bone regeneration materials and techniques holds substantial promise in rehabilitating anthropological parameters, improving patient outcomes, advancing medical technology, and contributing to a more comprehensive and ethical approach to healthcare