Relevance-Based Compression of Cataract Surgery Videos

In the last decade, the need for storing videos from cataract surgery has increased significantly. Hospitals continue to improve their imaging and recording devices (e.g., microscopes and cameras used in microscopic surgery, such as ophthalmology) to enhance their post-surgical processing efficiency. The video recordings enable a lot of user-cases after the actual surgery, for example, teaching, documentation, and forensics. However, videos recorded from operations are typically stored in the internal archive without any domain-specific compression, leading to a massive storage space consumption. In this work, we propose a relevance-based compression scheme for videos from cataract surgery, which is based on content specifics of particular cataract surgery phases. We evaluate our compression scheme with three state-of-the-art video codecs, namely H.264/AVC, H.265/HEVC, and AV1, and ask medical experts to evaluate the visual quality of encoded videos. Our results show significant savings, in particular up to 95.94% when using H.264/AVC, up to 98.71% when using H.265/HEVC, and up to 98.82% when using AV1.Comment: 11 pages, 5 figures, 3 table

Multifocal ERG in multiple evanescent white dot syndrome

PURPOSE: To investigate the electrophysiological findings of a multifocal ERG in multiple evanescent white dot syndrome (MEWDS). METHODS: Multifocal electroretinograms (mf-ERG) were recorded from four patients with MEWDS. The stimulus array consisted of 61 hexagons and was presented according to a binary m-sequence. We analyzed the N1- and P1-wave amplitudes as well as P1 latencies of the first-order kernels. Local responses and concentric ring averaged responses were compared to 20 age-matched normal subjects. All patients underwent fluorescein angiography and indocyanine green angiography. RESULTS: In two patients, first-order kernel of N1- and P1-wave amplitudes showed supernormal results at the very beginning (day 1 to day 7) of the disease. By 2 weeks later, N1- and P1-wave amplitudes had decreased to either normal or subnormal values. The two patients who presented 2 weeks after the onset of clinical signs showed subnormal or decreased amplitudes. The P1 implicit times were within normal limits in all patients. CONCLUSION: Our mf-ERG findings show different results during the course of the disease. First-order kernel amplitudes seem to reflect early disturbances of the photoreceptors in MEWDS and are therefore useful in detecting early stages and following up the disease

Ocular toxicity due to Trametinib and Dabrafenib

Abstract Background To report a case of uveitis and neuroretinal detachment in a patient treated with Trametinib and Dabrafenib due to metastatic cutaneous melanoma stage IV. Case presentation We evaluated slit lamp examination, fundoscopy, optical coherence tomography, fluorescein and indocyanine green angiography in a 66 years old man suffering visual loss. Fundoscopy showed serous neuroretinal detachment of the fovea accompanied with white spots surrounding the fovea in both eyes. Although therapy with Trametinib and Dabrafenib was stopped uveitis anterior was seen 2 weeks later. After a year, the therapy was started again and the serous neuroretinal detachment appeared once more, however without inflammatory reaction of the anterior chamber. Conclusion Patients treated with Trametinib and Dabrafenib should undergo consecutive eye examinations from the beginning of the therapy