22 research outputs found

    Aquifer potential assessment in termites manifested locales using geo-electrical and surface hydraulic measurement parameters

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    © 2019 by the authors. Licensee MDPI, Basel, Switzerland. In some parts of tropical Africa, termite mound locations are traditionally used to site groundwater structures mainly in the form of hand-dug wells with high success rates. However, the scientific rationale behind the use of mounds as prospective sites for locating groundwater structures has not been thoroughly investigated. In this paper, locations and structural features of termite mounds were mapped with the aim of determining the aquifer potential beneath termite mounds and comparing the same with adjacent areas, 10 m away. Soil and species sampling, field surveys and laboratory analyses to obtain data on physical, hydraulic and geo-electrical parameters from termite mounds and adjacent control areas followed. The physical and hydraulic measurements demonstrated relatively higher infiltration rates and lower soil water content on mound soils compared with the surrounding areas. To assess the aquifer potential, vertical electrical soundings were conducted on 28 termite mounds sites and adjacent control areas. Three (3) important parameters were assessed to compute potential weights for each Vertical Electrical Sounding (VES) point: Depth to bedrock, aquifer layer resistivity and fresh/fractured bedrock resistivity. These weights were then compared between those of termite mound sites and those from control areas. The result revealed that about 43% of mound sites have greater aquifer potential compared to the surrounding areas, whereas 28.5% of mounds have equal and lower potentials compared with the surrounding areas. The study concludes that termite mounds locations are suitable spots for groundwater prospecting owing to the deeper regolith layer beneath them which suggests that termites either have the ability to locate places with a deeper weathering horizon or are themselves agents of biological weathering. Further studies to check how representative our study area is of other areas with similar termite activities are recommended

    Cross-Location Analysis of the Impact of Household Socioeconomic Status on Participation in Urban and Peri-Urban Agriculture in West Africa

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    This study explores the relation between household socioeconomic status (SES) and participation in urban and periurban agriculture (UPA) in three West African cities. We used a structured questionnaire to survey 700 randomly selected households: 250 in Kano, Nigeria, 250 in Bobo Dioulasso, Burkina Faso, and 200 in Sikasso, Mali. Multiple correspondence analysis was applied on household asset variables to create an index of assets which was used as a proxy for household SES. The results showed no significant differences in households’ rate of participation in UPA across socioeconomic groups. Participation in UPA was rather significantly (P < 0.001) and positively related to household size. Interestingly, the analysis revealed that field crop cultivation and gardening were more common among households in the low and medium SES groups while those in the high SES group were more likely to keep livestock

    Increased peri-ductal collagen micro-organization may contribute to raised mammographic density

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    BACKGROUND: High mammographic density is a therapeutically modifiable risk factor for breast cancer. Although mammographic density is correlated with the relative abundance of collagen-rich fibroglandular tissue, the causative mechanisms, associated structural remodelling and mechanical consequences remain poorly defined. In this study we have developed a new collaborative bedside-to-bench workflow to determine the relationship between mammographic density, collagen abundance and alignment, tissue stiffness and the expression of extracellular matrix organising proteins. METHODS: Mammographic density was assessed in 22 post-menopausal women (aged 54–66 y). A radiologist and a pathologist identified and excised regions of elevated non-cancerous X-ray density prior to laboratory characterization. Collagen abundance was determined by both Masson’s trichrome and Picrosirius red staining (which enhances collagen birefringence when viewed under polarised light). The structural specificity of these collagen visualisation methods was determined by comparing the relative birefringence and ultrastructure (visualised by atomic force microscopy) of unaligned collagen I fibrils in reconstituted gels with the highly aligned collagen fibrils in rat tail tendon. Localised collagen fibril organisation and stiffness was also evaluated in tissue sections by atomic force microscopy/spectroscopy and the abundance of key extracellular proteins was assessed using mass spectrometry. RESULTS: Mammographic density was positively correlated with the abundance of aligned periductal fibrils rather than with the abundance of amorphous collagen. Compared with matched tissue resected from the breasts of low mammographic density patients, the highly birefringent tissue in mammographically dense breasts was both significantly stiffer and characterised by large (>80 μm long) fibrillar collagen bundles. Subsequent proteomic analyses not only confirmed the absence of collagen fibrosis in high mammographic density tissue, but additionally identified the up-regulation of periostin and collagen XVI (regulators of collagen fibril structure and architecture) as potential mediators of localised mechanical stiffness. CONCLUSIONS: These preliminary data suggest that remodelling, and hence stiffening, of the existing stromal collagen microarchitecture promotes high mammographic density within the breast. In turn, this aberrant mechanical environment may trigger neoplasia-associated mechanotransduction pathways within the epithelial cell population. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13058-015-0664-2) contains supplementary material, which is available to authorized users
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