Acute myocardial infarction and pulmonary tuberculosis in a young female patient: a case report

Abstract Introductio

Učinci kombinirane terapije reumatoidnog artritisa na reaktante akutne faze

The paper presents the results of studies of acute phase reactants in the 60 treated patients with rheumatoid arthritis. Patients were divided into two groups, depending on the applied treatment: group I (n=30) was treated with methotrexate, sulfasalazine and hydroxychloroquine, and group II (n=30) with methotrexate. The results of our study shows that there is a statistically significant reduction in the value of acute phase reactants and clinical parameters after treatment in both investigated groups of patients, and also a significant statistical difference between the first and second group of treated patients.U radu su prikazani rezultati ispitivanja reaktanata akutne faze u 60 liječenih bolesnika s reumatoidnim artritisom. Bolesnici su bili podijeljeni u dvije skupine, ovisno o primijenjenoj terapiji: I. skupina (n=30) je liječena metotreksatom, sulfasalazinom i hidroksiklorokinom, a II. skupina (n=30) metotreksatom. Rezultati našega istraživanja pokazuju da postoji statistički značajno smanjenje vrijednosti reaktanata akutne faze i kliničkih parametara nakon liječenja u obje ispitivane skupine bolesnika, a također i značajna statistička razlika između prve i druge skupine liječenih bolesnika

Association of interatrial septal abnormalities with cardiac impulse conduction disorders in adult patients: experience from a tertiary center in Kosovo

Interatrial septal disorders, which include: atrial septal defect, patent foramen ovale and atrial septal aneurysm, are frequent congenital anomalies found in adult patients. Early detection of these anomalies is important to prevent their hemodynamic and/or thromboembolic consequences. The aims of this study were: to assess the association between impulse conduction disorders and anomalies of interatrial septum; to determine the prevalence of different types of interatrial septum abnormalities; to assess anatomic, hemodynamic, and clinical consequences of interatrial septal pathologies. Fifty-three adult patients with impulse conduction disorders and patients without ECG changes but with signs of interatrial septal abnormalities, who were referred to our center for echocardiography, were included in a prospective transesophageal echocardiography study. Interatrial septal anomalies were detected in around 85% of the examined patients. Patent foramen ovale was encountered in 32% of the patients, and in combination with atrial septal aneurysm in an additional 11.3% of cases. Atrial septal aneurysm and atrial septal defect were diagnosed with equal frequency in 20.7% of our study population. Impulse conduction disorders were significantly more suggestive of interatrial septal anomalies than clinical signs and symptoms observed in our patients (84.91% vs 30.19%, P=0.002). Right bundle branch block was the most frequent impulse conduction disorder, found in 41 (77.36%) cases. We conclude that interatrial septal anomalies are highly associated with impulse conduction disorders, particularly with right bundle branch block. Impulse conduction disorders are more indicative of interatrial septal abnormalities in earlier stages than can be understood from the patient’s clinical condition