13 research outputs found

    Study of temporal and spatial variations of physical parameters (temperature, salinity and density) trend of the Pozm Bay

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    Pozm bay Located in southern coast of Iran near Oman Sea, due to its relative calmness, low depth and being affected by the land substances is interesting to some aquatics species for reproduction and spending part of their growth period. In this research the seasonal variations of physical parameters trend of the Pozm pay was investigated during 9 periods since Oct 2011 till Aug 2012. The physical parameters of the sea water were measured by the CTD device in 17 stations from surface to seabed. These parameters are as follows: Temperature, Salinity, Density, Electrical conductivity, Sound velocity, Turbidity, and the Dissolved oxygen. According to the results of this research, the variations of the water temperature are following the air temperature and increase as the air temperature arises in hot seasons. Although due to the low depth of Pozm bay the formation of thermocline layer and water stratification are so low, weak stratification is formed in water column during hot months of the year. The entering flow of Oman Sea water into the Persian Gulf, which is less salty comparing to that of Persian Gulf, is maximized during late spring and minimized in winter and affects the salinity of Pozm bay water such that its rate is more during mild months than hot months. The variation of the density is influenced by water temperature and the salinity has no effect on them. The summer monsoon has a significant effect on the physical parameters of Pozm bay's water

    NIR triggered glycosylated gold nanoshell as a photothermal agent on melanoma cancer cells

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    Nowadays, gold nanoshells are used in targeted nano photothermal cancer therapy. This study surveyed the application of gold nanoshell (GNs) to thermal ablative therapy for melanoma cancer cells and it takes advantage of the near infrared absorption of gold nanoshells. The synthesis and characterization of glycosylated gold nanoshells (GGNs) were done. The cytotoxicity and photothermal effects of GNs on melanoma cells were evaluated using MTT assay and flow cytometry. The characterization data showed that GGNs are spherical, with a hydrodynamic size of 46.7 nm. Results suggest that the cellular uptake of GGNs was about 78. Viability assays showed no significant toxicity at low concentrations of GNs. The higher heating rate and toxicity of cancer cells were obtained for the cells exposed to 808 nm NIR laser after incubation with GGNs rather than the GNs. The viability of these cells has dramatically decreased by 29. Furthermore, 61 more cell lethality was achieved for A375 cells using combined photothermal therapy and treatment with GGNs in comparison to NIR radiation alone. In conclusion, our findings suggest that the synthesized gold/silica core-shell nanoparticles conjugated with glucosamine have high potentials to be considered as an efficient metal-nanoshell in the process of targeted cancer photothermal therapy. © 2019, © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group
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