Tune in™ to Reading, an interactive singing computer program, and children who are deaf or hard of hearing using cochlear implants: Could this program be effective in improving reading fluency?

A literature review of reading fluency and music production with an analysis of Tune in™ to Reading and its potential to improve reading fluency in children who are deaf or hard of hearing using cochlear implants

Gaussian cubature arising from hybrid characters of simple Lie groups

Lie groups with two different root lengths allow two mixed sign homomorphisms on their corresponding Weyl groups, which in turn give rise to two families of hybrid Weyl group orbit functions and characters. In this paper we extend the ideas leading to the Gaussian cubature formulas for families of polynomials arising from the characters of irreducible representations of any simple Lie group, to new cubature formulas based on the corresponding hybrid characters. These formulas are new forms of Gaussian cubature in the short root length case and new forms of Radau cubature in the long root case. The nodes for the cubature arise quite naturally from the (computationally efficient) elements of finite order of the Lie group.Comment: 23 pages, 3 figure

The nucleotide sequence of the variable region in Trypanosoma brucei completes the sequence analysis of the maxicircle component of mitochondrial kinetoplast DNA

The nucleotide sequence of two non-contiguous DNA fragments of 4.0 and 2.2 kb, respectively, of the kinetoplast maxicircle of Trypanosoma brucei brucei EATRO strain 427 has been determined, completing the sequence analysis of the so-called variable region (see also de Vries et al., 1988, Mol. Biochem. Parasitol. 27, 71-82). Analysis of the entire 8-kb variable region sequence revealed the presence of a 5.2-kb cluster of imperfect, tandemly repeated sequences, flanked by DNA of unique sequence. Both repetitive and unique DNA evolve rapidly, but comparison to the closely related strain EATRO 164 indicated that the repetitive cluster is more prone to sequence and size divergence. The variable region is transcribed into RNAs of varying lengths but appears to be devoid of genes encoding mitochondrial proteins or tRNAs, as judged from computer analysis. Moreover, genes that could encode guide RNAs involved in producing the known edited mitochondrial mRNA sequences are also absent. The repetitive DNA cluster within this region consists of 14 blocks each containing one 130 bp repeat and a variable number of 19 bp repeats. A duplicated sequence was identified (5'-GGGGTTGGTGT) which proved to be identical to the eleven 5'-terminal residues of the universal minicircle dodecamer involved in initiation of leading strand synthesis. This suggests a role for these sequences in the initiation of maxicircle DNA replication. With the data presented in this report, the nucleotide sequence analysis of the 23016 bp maxicircle of T. brucei brucei EATRO strain 427 has been complete