3 research outputs found
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Macrophage Tropism and Antibody Neutralization Resistance of HIV-1 is Conferred by the Envelope Protein gp120
This MQP investigated the viral tropism and neutralizing antibody sensitivities of gp120 and gp41 sequences of three parental HIV-1 strains (Q43-378.2, Q43-378.c, and SQ43-380.1) isolated from a single patient, and of various engineered chimeras. The data indicate that gp120 alone is able to confer macrophage tropism, while gp41 has no noticeable effect on tropism. The data further indicate that gp41 has no visible effect on the resistance to a b12 antibody that reacts with the CD4-binding domain on gp-120, and that gp120 sequences are the most likely cause of neutralization resistance
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Stem Cells
Stem cell research is a controversial topic that strongly affects society, but misinformation to the public complicates the issue. This IQP clarifies the types and sources of stem cells, discusses their applications, and outlines the religious and political opposition that make support for the research difficult. We hope the public will read this report open mindedly to formulate their own educated opinion on this complex topic