376 research outputs found

    Sequences of Willmore surfaces

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    In this paper we develop the theory of Willmore sequences for Willmore surfaces in the 4-sphere. We show that under appropriate conditions this sequence has to terminate. In this case the Willmore surface either is the twistor projection of a holomorphic curve into complex projective space or the inversion of a minimal surface with planar ends in 4-space. These results give a unified explanation of previous work on the characterization of Willmore spheres and Willmore tori with non-trivial normal bundles by various authors.Comment: 10 page

    Is diagnosis enough to guide interventions in mental health? Using case formulation in clinical practice

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    While diagnosis has traditionally been viewed as an essential concept in medicine, particularly when selecting treatments, we suggest that the use of diagnosis alone may be limited, particularly within mental health. The concept of clinical case formulation advocates for collaboratively working with patients to identify idiosyncratic aspects of their presentation and select interventions on this basis. Identifying individualized contributing factors, and how these could influence the person\u27s presentation, in addition to attending to personal strengths, may allow the clinician a deeper understanding of a patient, result in a more personalized treatment approach, and potentially provide a better clinical outcome.<br /

    NR4A Gene Expression Is Dynamically Regulated in the Ventral Tegmental Area Dopamine Neurons and Is Related to Expression of Dopamine Neurotransmission Genes

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    The NR4A transcription factors NR4A1, NR4A2, and NR4A3 (also known as Nur77, Nurr1, and Nor1, respectively) share similar DNA-binding properties and have been implicated in regulation of dopamine neurotransmission genes. Our current hypothesis is that NR4A gene expression is regulated by dopamine neuron activity and that induction of NR4A genes will increase expression of dopamine neurotransmission genes. Eticlopride and γ-butyrolactone (GBL) were used in wild-type (+/+) and Nurr1-null heterozygous (+/−) mice to determine the mechanism(s) regulating Nur77 and Nurr1 expression. Laser capture microdissection and real-time PCR was used to measure Nurr1 and Nur77 mRNA levels in the ventral tegmental area (VTA). Nur77 expression was significantly elevated 1 h after both GBL (twofold) and eticlopride (fourfold). In contrast, GBL significantly decreased Nurr1 expression in both genotypes, while eticlopride significantly increased Nurr1 expression only in the +/+ mice. In a separate group of mice, haloperidol injection significantly elevated Nur77 and Nor1, but not Nurr1 mRNA in the VTA within 1 h and significantly increased tyrosine hydroxylase (TH) and dopamine transporter (DAT) mRNA expression by 4 h. These data demonstrate that the NR4A genes are dynamically regulated in dopamine neurons with maintenance of Nurr1 expression requiring dopamine neuron activity while both attenuation of dopamine autoreceptors activation and dopamine neuronal activity combining to induce Nur77 expression. Additionally, these data suggest that induction of NR4A genes could regulate TH and DAT expression and ultimately regulate dopamine neurotransmission

    Mean Curvature Flow of Spacelike Graphs

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    We prove the mean curvature flow of a spacelike graph in (ÎŁ1×Σ2,g1−g2)(\Sigma_1\times \Sigma_2, g_1-g_2) of a map f:ÎŁ1→Σ2f:\Sigma_1\to \Sigma_2 from a closed Riemannian manifold (ÎŁ1,g1)(\Sigma_1,g_1) with Ricci1>0Ricci_1> 0 to a complete Riemannian manifold (ÎŁ2,g2)(\Sigma_2,g_2) with bounded curvature tensor and derivatives, and with sectional curvatures satisfying K2≀K1K_2\leq K_1, remains a spacelike graph, exists for all time, and converges to a slice at infinity. We also show, with no need of the assumption K2≀K1K_2\leq K_1, that if K1>0K_1>0, or if Ricci1>0Ricci_1>0 and K2≀−cK_2\leq -c, c>0c>0 constant, any map f:ÎŁ1→Σ2f:\Sigma_1\to \Sigma_2 is trivially homotopic provided f∗g2<ρg1f^*g_2<\rho g_1 where ρ=min⁥Σ1K1/sup⁥Σ2K2+≄0\rho=\min_{\Sigma_1}K_1/\sup_{\Sigma_2}K_2^+\geq 0, in case K1>0K_1>0, and ρ=+∞\rho=+\infty in case K2≀0K_2\leq 0. This largely extends some known results for KiK_i constant and ÎŁ2\Sigma_2 compact, obtained using the Riemannian structure of ÎŁ1×Σ2\Sigma_1\times \Sigma_2, and also shows how regularity theory on the mean curvature flow is simpler and more natural in pseudo-Riemannian setting then in the Riemannian one.Comment: version 5: Math.Z (online first 30 July 2010). version 4: 30 pages: we replace the condition K1≄0K_1\geq 0 by the the weaker one Ricci1≄0Ricci_1\geq 0. The proofs are essentially the same. We change the title to a shorter one. We add an applicatio

    On the Evolution Equation for Magnetic Geodesics

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    In this paper we prove the existence of long time solutions for the parabolic equation for closed magnetic geodesics.Comment: In this paper we prove the existence of long time solutions for the parabolic equation for closed magnetic geodesic

    QCD Strings as Constrained Grassmannian Sigma Model:

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    We present calculations for the effective action of string world sheet in R3 and R4 utilizing its correspondence with the constrained Grassmannian sigma model. Minimal surfaces describe the dynamics of open strings while harmonic surfaces describe that of closed strings. The one-loop effective action for these are calculated with instanton and anti-instanton background, reprsenting N-string interactions at the tree level. The effective action is found to be the partition function of a classical modified Coulomb gas in the confining phase, with a dynamically generated mass gap.Comment: 22 pages, Preprint: SFU HEP-116-9

    THE UNIQUENESS THEOREM FOR ROTATING BLACK HOLE SOLUTIONS OF SELF-GRAVITATING HARMONIC MAPPINGS

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    We consider rotating black hole configurations of self-gravitating maps from spacetime into arbitrary Riemannian manifolds. We first establish the integrability conditions for the Killing fields generating the stationary and the axisymmetric isometry (circularity theorem). Restricting ourselves to mappings with harmonic action, we subsequently prove that the only stationary and axisymmetric, asymptotically flat black hole solution with regular event horizon is the Kerr metric. Together with the uniqueness result for non-rotating configurations and the strong rigidity theorem, this establishes the uniqueness of the Kerr family amongst all stationary black hole solutions of self-gravitating harmonic mappings.Comment: 18 pages, latex, no figure

    On paraquaternionic submersions between paraquaternionic K\"ahler manifolds

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    In this paper we deal with some properties of a class of semi-Riemannian submersions between manifolds endowed with paraquaternionic structures, proving a result of non-existence of paraquaternionic submersions between paraquaternionic K\"ahler non locally hyper paraK\"ahler manifolds. Then we examine, as an example, the canonical projection of the tangent bundle, endowed with the Sasaki metric, of an almost paraquaternionic Hermitian manifold.Comment: 13 pages, no figure

    Remarks on symplectic twistor spaces

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    We consider some classical fibre bundles furnished with almost complex structures of twistor type, deduce their integrability in some cases and study \textit{self-holomorphic} sections of a \textit{symplectic} twistor space. With these we define a moduli space of ω\omega-compatible complex structures. We recall the theory of flag manifolds in order to study the Siegel domain and other domains alike, which is the fibre of the referred twistor space. Finally the structure equations for the twistor of a Riemann surface with the canonical symplectic-metric connection are deduced, based on a given conformal coordinate on the surface. We then relate with the moduli space defined previously.Comment: 20 pages, title changed since v2, accepted in AMPA toda
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