Effects of a Vitamin B-deficient diet during pregnancy on total GSH, reduced GSH and GSSG concentrations, and GSH/GSSG ratios in the brain of offspring at PND 0.

<p>n = 6–8; PND  =  Postnatal day; CT  =  control; DP  =  deficient diet during pregnancy; GSH  =  glutathione; GSSG  =  oxidized glutathione. <i>t test</i>. Data are presented as the mean ± standard error.</p

Effects of a Vitamin B-deficient diet during pregnancy and pregnancy/lactation on plasma and brain cortex parameters in offspring at PND 28.

<p>n = 6–8; PND  =  postnatal day; CT  =  control; DP  =  deficient diet during pregnancy; DPL  =  deficient during pregnancy and lactation; Hcy  =  homocysteine; Cys  =  Cysteine; GSH  =  glutathione; GSSG  =  oxidized glutathione; SAM  =  S-adenosylmethionine; SAH  =  S-adenosylhomocysteine. <i>ANOVA</i>. Data are presented as the mean ± standard error. ^*Different from the CT group (<i>P</i>≤0.05). ^#Difference between DP and DPL groups (<i>P</i>≤0.05). <i>t test</i>, § Difference between female and male control (<i>P</i>≤0.05).</p

Plasma Hcy concentration in dams after twenty days on an experimental diet.

<p>n = 6–8; PND  =  Postnatal day; CT  =  control; DDD  =  dams in deficient diet. <i>t test</i>. Data are presented as the mean ± standard error. ^*<i>P</i>≤0.05.</p

Effects of a Vitamin B-deficient diet during pregnancy on SAM and SAH concentrations and SAM/SAM ratios in the brain of male offspring at PND 0.

<p>n = 6–8; PND  =  Postnatal day; CT  =  control; DP  =  deficient diet during pregnancy; SAM  =  S-adenosylmethionine; SAH  =  S-adenosylhomocysteine. <i>t test</i>. Data are presented as the mean ± standard error. ^*<i>P</i>≤0.05.</p