1 research outputs found
Risk factors for diabetic autonomic cardiovascular neuropathy in children and adolescents with type 1 diabetes mellitus
Aim.
To determine risk factors for diabetic autonomic cardiovascular neuropathy (DACN) and to optimize diagnostic procedures forĀ children and adolescents with type 1 diabetes mellitus.
Materials and methods.
Heart rate variability (HRV) was assessed in 101 subjects with type 1 diabetes mellitus aged 5?17 y.o.Ā in 4 functional tests. Subjects with 3 positive tests out 4 were considered positive for DACN.
Results.
Increased glycemic variability (9+ mmol/l per day), regular hypoglycemic events and late diabetes complications were found to be DACN risk factors in children and adolescents.
Conclusions.
A diagnostic algorithm for DACN in children and adolescents with type 1 diabetes mellitus based on orthostatic HRV variability assessment shows high sensitivity and efficiency