4,354 research outputs found

    The Provincial Chronicle: Special Marian Issue

    Get PDF
    Special issue of the quarterly provincial periodical for the 1953-1954 Marian Year. Article topics include the role of the Blessed Virgin Mary in Franciscan charism and the patronage of Mary Immaculate

    Note and Comment

    Get PDF
    Sales - Liability for the Presence of Mice and Other Uncommon Things in Food - A group of recent decisions presents a somewhat farcical conformity with Montesquiet\u27. thesis that law may vary with time and geography. It strikingly illustrates, also, the importance of the particular theory of liability upon which a suit is predicated. The unusual similarity in detail of the operative facts of these cases lends peculiar emphasis to the difference in the judgments rendered

    Characterization of the Rapid Proteolytic Shedding of Murine L-Selectin

    Get PDF
    The structural requirements for L-selectin shedding were studied in murine leukocytes. Upon activation, L-selectin on both lymphocytes and neutrophils undergoes cleavage by a membrane metalloprotease, resulting in the generation of a soluble ectodomain and a membrane- retained 6 kD fragment. Radiochemical sequencing demonstrated a cleavage site in the membrane-proximal region (MPR) between R321 and S322, which is homologous to the human site. Although intact neutrophil L-selectin is larger, it is cleaved at the same, or very close, site. Analysis of several transfectants expressing L-selectin point mutations and chimeric constructs suggest that, like human shedding, the proteolytic process has relatively loose sequence specificity for the substrate site. In addition, some constructs are susceptible to slow constitutive cleavage, but their shedding does not increase upon PMA stimulation, showing that basal and activated shedding are separable processes. Insertion of the 15 amino acid MPR into murine B7.2 conferred upon this molecule susceptibility to constitutive shedding. PMA stimulation results in little or no acceleration of down regulation of this molecule. These results suggest that recognition of both the membrane-proximal cleavage site and of a site distant from the MPR are required for maximal induction of L-selectin shedding

    Optical spectra and thermal Schottky levels in dysprosium sesquisulfide

    Full text link
    We report a detailed crystal-field splitting analysis of the energy levels of Dy3+(4f9)Dy3+(4f9) in single crystals of Dy2S3Dy2S3 that have the Th3P4Th3P4 cubic defect structure. From an analysis of the temperature-dependent absorption spectra, we have identified seven of the eight crystal-field split energy (Stark) levels of the ground-state multiplet manifold, 6H15/2.6H15/2. Sixty-two experimental Stark levels from various multiplet manifolds of Dy3+Dy3+ are compared with a calculated crystal-field splitting, whose initial crystal-field parameters, Bnm,Bnm, were determined from lattice-sum calculations. The rms deviation between experimental and calculated levels is 7 cm−1. Both the experimental and calculated crystal-field splitting of the 6H15/26H15/2 manifold are compared with an assignment of Schottky levels obtained from a reassessment of heat capacity data reported earlier. Based on entropy considerations and verification of the Schottky level assignments by analyses of the optical and magnetic susceptibility data, we conclude that the anomaly observed in the heat capacity data near 3.4 K is due to antiferromagnetic ordering. © 1999 American Institute of Physics.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69677/2/JCPSA6-110-24-12125-1.pd

    Studies of the Electromotive Force in Biological Systems: IV. The Effect of Carbon Monoxide on the E. M. F. of Frog Skin

    Get PDF
    Using a method similar to that previously reported by Steinbach (1933), Pumphrey and Francis (1933), and others the authors have studied the effect of different carbon monoxide-oxygen mixtures upon the inherent E. M. F. of pieces of isolated frog skin

    Concepts for Life Cycle Cost Control Required to Achieve Space Transportation Affordability and Sustainability

    Get PDF
    Cost control must be implemented through the establishment of requirements and controlled continually by managing to these requirements. Cost control of the non-recurring side of life cycle cost has traditionally been implemented in both commercial and government programs. The government uses the budget process to implement this control. The commercial approach is to use a similar process of allocating the non-recurring cost to major elements of the program. This type of control generally manages through a work breakdown structure (WBS) by defining the major elements of the program. If the cost control is to be applied across the entire program life cycle cost (LCC), the approach must be addressed very differently. A functional breakdown structure (FBS) is defined and recommended. Use of a FBS provides the visibifity to allow the choice of an integrated solution reducing the cost of providing many different elements of like function. The different functional solutions that drive the hardware logistics, quantity of documentation, operational labor, reliability and maintainability balance, and total integration of the entire system from DDT&E through the life of the program must be fully defined, compared, and final decisions made among these competing solutions. The major drivers of recurring cost have been identified and are presented and discussed. The LCC requirements must be established and flowed down to provide control of LCC. This LCC control will require a structured rigid process similar to the one traditionally used to control weight/performance for space transportation systems throughout the entire program. It has been demonstrated over the last 30 years that without a firm requirement and methodically structured cost control, it is unlikely that affordable and sustainable space transportation system LCC will be achieved

    Nurses\u27 Alumnae Association Bulletin - Volume 16 Number 1

    Get PDF
    Alumnae Notes ANA Biennial Convention Cancer of the Cervix, Uterus and Ovaries Committee Reports Digest of Alumnae Association Meetings Greetings from Miss Childs Greetings from the President Graduation Awards - 1950 Isotopes and the Nurse - Dr. T.P. Eberhard Marriages Necrology New Arrivals Nursing Care in Heart Disease with Pulmonary Infarction Nursing Care of a Mitral Commissurotomy Physical Advances at Jefferson - 1950 Policies of the Private Duty Nurses\u27 Registry Staff Activities, 1950-1951 Students\u27 Corner The Department of Surgical Research - Drs. Templeton and Gibbon White Haven and Barton Memorial Division

    Thermophysical properties of the lanthanide sesquisulfides. III. Determination of Schottky and lattice heat‐capacity contributions of γ‐phase Sm2S3 and evaluation of the thermophysical properties of the γ‐phase Ln2S3 subset

    Full text link
    We report the experimental heat capacity of γ‐phase Sm2S3 and derived thermophysical properties at selected temperatures. The entropy, enthalpy increments, and Gibbs energy function are 21.50R, 3063R⋅K, and 11.23R at 298.15 K. The experimental heat capacity is made up of lattice and electronic (Schottky) contributions. The lattice contribution is determined for all γ‐phase lanthanide sesquisulfides (Ln2S3 ) using the Komada/Westrum model. The difference between the experimental heat capacity and the deduced lattice heat capacity is analyzed as the Schottky contribution. Comparisons are made between the calorimetric Schottky contributions and those determined based on crystal‐field electronic energy levels of Ln3+ ions in the lattice and between the Schottky contributions obtained from the empirical volumetric priority approach and from the Komada/Westrum theoretical approach. Predictions for the thermophysical properties of γ‐phase Eu2S3 and γ‐phase Pm2S3 (unavailable for experimental determination) are also presented.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71137/2/JCPSA6-96-8-6149-1.pd

    Circadian regulation of olfaction and an evolutionarily conserved, nontranscriptional marker in Caenorhabditis elegans

    Get PDF
    Circadian clocks provide a temporal structure to processes from gene expression to behavior in organisms from all phyla. Most clocks are synchronized to the environment by alternations of light and dark. However, many organisms experience only muted daily environmental cycles due to their lightless spatial niches (e.g., caves or soil). This has led to speculation that they may dispense with the daily clock. However, recent reports contradict this notion, showing various behavioral and molecular rhythms in Caenorhabditis elegans and in blind cave fish. Based on the ecology of nematodes, we applied low-amplitude temperature cycles to synchronize populations of animals through development. This entrainment regime reveals rhythms on multiple levels: in olfactory cued behavior, in RNA and protein abundance, and in the oxidation state of a broadly conserved peroxiredoxin protein. Our work links the nematode clock with that of other clock model systems; it also emphasizes the importance of daily rhythms in sensory functions that are likely to impact on organism fitness and population structure

    Thermophysical properties of the lanthanide sesquisulfides. IV. Schottky contributions, magnetic, and electronic properties of ϵ‐phase Yb2S3 and Lu2S3

    Full text link
    The heat capacities of ϵ‐phase Yb2S3 and Lu2S3 have been determined from 6 to 350 K and their thermodynamic properties evaluated. The resolution of the Schottky and magnetic properties by evaluation of the lattice heat capacity is shown to be in accord with spectroscopically determined energy levels. The lattice heat capacity of Yb2S3 was determined by means of the Komada–Westrum phonon distribution model. Excess heat‐capacity contributions were thus evaluated and analyzed as Schottky and magnetic heat capacities. A phase transition associated with magnetic ordering was detected in the heat capacity of Yb2S3 near 7 K with an entropy content of 0.68R. The entropies at 298.15 K are 22.77R and 19.74R for Yb2S3 and for Lu2S3.  Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70016/2/JCPSA6-98-2-1458-1.pd
    corecore