398 research outputs found
Living Labs as Tools for Open Innovation
This paper presents a Living Lab in Stockholm as a focal point for discussing how the Living Lab concept can be extended and used for engaging in multiorganizational open innovation. Although Living Labs have been found to have potential for driving innovation through collaboration, more research is necessary to find tangible ways of organizing this kind of collaboration. The paper is explorative and empirically induced from an ongoing development and practical implementation of a Living Lab at Stockholm-Arlanda Airport - Sweden's largest airport situated outside Stockholm. This Airport Living Lab involves a number of large industrial and academic stakeholders aiming at ensuring multi-organizational innovation delivery. Of special interest is how the Living Lab concept should evolve to continue creating conditions for user-oriented innovations through multi-organizational collaboration which would not necessarily take place otherwise. Congruent with the explorative aim of the paper it ends up in a discussion about five propositions that should be on the agenda of research and implementation for Living Lab founders in the coming years.Living Labs, Open innovation, Electronic Collaboration Tools
Anchoring Tablets in Organizational Practices - a Practice Based Approach to the Digitalization of Board Work
Drawing on new technologies, decision makers attempt to design and make real visions for the future of organizations and society. Aiming for successful enactment, instead they are often faced with resistance or unintended changes to existing practices and values. This paper addresses this challenge from a practice theory perspective. Taking our departure in the reflexive dualities of practices and constitutive rules, we present and put into action an analytical model to shed light on how IS-enabled organizational change is enabled and sustained via dynamic interplay, inherent relations and performative enactment. The empirical material consists of interviews and observations in a Swedish municipality. The contribution includes an account as to how the enactment and definition of fundamental social relations affect the introduction of digital board packs via tablets to either serve as a catalyst to establish and reproduce new setups and practices in the board room or simply fail
Adopting Proactive Knowledge Use as an Innovation: The Case of a Knowledge Management System in Rheumatology
The aim of the study is to present a tentative framework to explore and investigate the drivers and barriers of adoption of the innovation of proactive knowledge use in connection to a knowledge management system (KMS) in health care. Semi-structured interviews were performed with champion implementers and physicians using the KMS along with a document analysis depicting significant events of the implementation process. The findings from the study suggested that drivers of the innovation were the characteristics of change agents, quality improvement, budget control and knowledge brought to the physician-patient dialogue by the KMS. In particular, there were indications of the KMS facilitating the process of making tacit knowledge explicit in the physician-patient dialogue. Identified barriers towards the innovation were resistance from clinical management, lack of motivation to share knowledge, lack of time and perceived flaws in the interface and compilation of data in the KMS
Through the Printing Press: An Account of Open Practices in the Swedish Newspaper Industry
Organizational practices that foster a dialogic relationship between organizations and their constituent customers have created an arena for inbound and outbound innovation. At the nexus of this development occurring in the media industries, these flows are carried by various forms of digital, social media and an increasing digital presence in the form of dynamic websites with varying degrees of interactive capabilities. In this paper, we posit that the newspaper industry is torn between indifference and cautious apprehension caused by the difficulty in marrying the journalism professionâs carefully guarded gatekeeping practices with the revolving doors of open innovation. Gatekeeping has emerged as a fiercely defended cornerstone for the industry and the profession of journalism itself is not enough to distinguish amateurs from professionals; for the segregation between professionals and amateurs to carry weight rather than being reduced to a hollow title, the segregation needs a practice that explicitly enforces gatekeepingâwhere actions speak louder than titles. Against this backdrop, we pursue the following research question: Why has IT-enabled open innovation become such a contentious issue in the context of the newspaper industry? Combining contextual in-situ ethnographic interviews and observation with an industry-wide content analysis of Swedish newspaper websites, we present an in-depth view of what IT-enabled open innovation means in the context of the newspaper industry. Results show that the process of legitimization inscribed by a particularly charged information technologyâthe printing pressâcontinues to exert great influence in what constitutes open practice in the newspaper industry
Kunskap om Vilt och Skog 2
⹠ReferenshÀgn innebÀr att man jÀmför vegetationsutvecklingen i en hÀgnad yta med en oskyddad yta.
⹠ReferenshÀgn byggs med fördel i ungskogsytor dÀr
effekterna av betning Àr sÀrskilt tydliga.
⹠Hjortviltet kan genom bete pÄverka olika trÀdslags konkurrensförmÄga genom att höjdtillvÀxten minskar.
⹠Det Àr framför allt tall och flera arter av lövtrÀd som
pÄverkas negativt av bete medan gran ofta gynnas, vilket
pÄ sikt kan fÄ negativa konsekvenser för den biologiska
mÄngfalden.
⹠Genom att anvÀnda flera referenshÀgn kan man mÀta vilken
pÄverkan hjortviltet har pÄ vegetation och trÀdslagssammansÀttning inom ett viltförvaltningsomrÄde
Innovations in Health Care: Design Theory and Realist Evaluation Combined
Innovations in health care are often characterized by complexity and fuzzy boundaries, involving both the elements of the innovation and the organizational structure required for a full implementation. Evaluation in health care is traditionally based on the collection and dissemination of evidence-based knowledge stating the randomized controlled trial, and the quasi-experimental study design as the most rigorous and ideal approaches. These evaluation approaches capture neither the complexity of innovations in health care, nor the characteristics of the organizational structure of the innovation. As a result, the reasons for innovations in health care not being disseminated are not fully explained. The aim of the paper is to present a design-evaluation framework for complex innovations in health care in order to understand what works for whom under what circumstances combining design theory and realist evaluation. The framework is based on research findings of a case study of a complex innovation, a health care quality register, in order to understand underlying assumptions behind the design of the innovation, as well as the characteristics of the implementation process. The design-evaluation cycle is hypothesized to improve the design and implementation of complex innovation by using program/kernel theories to develop design principles, which are evaluated by realistic evaluation, resulting in further refinement of program/kernel theories. The goal of the design-evaluation cycle is to provide support to implementers and practitioners designing and implementing complex innovations in health care, for improving dissemination of complex innovations
Habitatmodeller och flermÄlsanalys
⹠Inom forskningsprogrammet Heureka utvecklas habitatmodeller för flera djur- och vÀxtarter. ⹠Habitatmodeller kan anvÀndas för att identifiera framtida flaskhalsar i mÀngd och fördelning av viktiga livsmiljöer för olika arter. ⹠Det behövs verktyg för att ta hÀnsyn till bÄde virkesproduktion och en viss mÀngd habitat i landskapet i planeringen. Ett sÄdant verktyg Àr flermÄlsanalys. ⹠FlermÄlsanalys kan anvÀndas för att utvÀrdera olika planalternativ med hÀnsyn till olika arters habitatkrav. Den grundliga genomgÄngen av situationen i en flermÄlsanalys ökar kunskapen om problemet vilket i sin tur kan leda till bÀttre slutlösningar
Interacting effects of insect and ungulate herbivory on Scots pine growth
Most plants are subjected to damage from multiple species of herbivores, and the combined impact on plant growth can be non-additive. Since plant response to herbivores tends to be species specific, and change with repeated damage, the outcome likely depend on the sequence and number of attacks. There is a high likelihood of non-additive effects on plant growth by damage from mammals and insects, as mammalian herbivory can alter insect herbivore damage levels, yet few studies have explored this. We report the growth response of young Scots pine trees to sequential mammal and insect herbivory, varying the sequence and number of damage events, using an ungulate-pine-sawfly system. Combined sawfly and ungulate herbivory had both additive and non-additive effects on pine growth-the growth response depended on the combination of ungulate browsing and sawfly defoliation (significant interaction effect). Repeated sawfly herbivory reduced growth (compared to single defoliation) on un-browsed trees. However, on browsed trees, depending on when sawfly defoliation was combined with browsing, trees exposed to repeated sawfly herbivory had both higher, lower and the same growth as trees exposed to a single defoliation event. We conclude that the sequence of attacks by multiple herbivores determine plant growth response
Evolutionary conservation and characterization of the metazoan amino acid response
Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy
at the
Massachusetts Institute of Technology
and the
Woods Hole Oceanographic Institution
February 2018Signaling pathways that respond to stress and sense nutrient availability are highly conserved throughout
eukaryotes. In mammalian cells, these pathways have evolved to regulate immune responses,
representing important therapeutic targets. Interestingly, components of these pathways can be found in
plants, yeast and nematodes, where they also participate in response to abiotic and biotic stress. The
Amino Acid Response (AAR) pathway, an ancient response to the cellular accumulation of uncharged
tRNA, is part of the larger Integrated Stress Response (ISR) in mammals. The ISR consists of multiple
branches, each one triggered by distinct stresses that produce phospho-eIF2α signal generation. Each ISR
initiating stress results in a unique cellular response due to activation of both the ISR and additional
parallel pathway(s) by the initiating stress, but, to date, no such alternate pathway has been identified for
the AAR pathway. Despite its integral role in stress adaptation, the ISR has not been studied in early
diverging animals. I have identified a highly conserved phosphorylation site in the protein eIF2α, the
signature ISR effector, which allowed me to use a mammalian antibody to identify and characterize the
ISR in the basal metazoan, Nematostella vectensis, revealing that the core components of the mammalian
ISR were present over 550 million years ago in the common ancestor of cnidarians and bilaterians.
Additionally, our lab has discovered a novel branch of the AAR pathway that regulates key tissue
protective signals. Using evolutionary conservation of this pathway in model organisms, I have identified
GCN1 as the branch point that links the signal generation components of the AAR pathway to
downstream therapeutic effects. I then used transcriptomic and protein interaction analyses to begin to
understand the scope of this pathway and identify key pathway regulators.Funding for this research was provided by the National Science Foundation Graduate Research
Fellowship Program, Allied Bristol Life Sciences (to Malcolm Whitman), the WHOI Academic Programs
Office, and the WHOI Ocean Venture Fund
Traitâmediated indirect interactions: Moose browsing increases sawfly fecundity through plantâinduced responses
1. Induced responses in plants, initiated by herbivory, create potential for traitâmediated indirect interactions among herbivores. Responses to an initial herbivore may change a number of plant traits that subsequently alter ecological processes with additional herbivores. Although common, indirect interactions between taxonomically distant herbivores, such as mammals and insects, are less studied than between taxonomically related species (i.e., insectâinsect). In terms of mammalâ insect interactions, effects on insect numbers (e.g., density) are relatively well studied, whereas effects on performance (e.g., fecundity) are rarely explored. Moreover, few studies have explored mammalâinsect interactions on coniferous plants. 2. The aim of this study was to investigate the effect of mammalian induced responses on insect performance. We specifically investigated the effect of moose (Alces alces) browsing on Scots pine (Pinus sylvestris) and subsequent effects on sawfly (Neodiprion sertifer) performance. 3. Sawfly larvae were reared on browsed, clipped, and unbrowsed control pine trees in a controlled field experiment. Afterward, cocoon weight was measured. Needle C:N ratio and diâterpene content were measured in response to browsing. 4. Sawfly performance was enhanced on trees browsed by moose. Cocoon weight (proxy for fecundity) was 9 and 13% higher on browsed and clipped trees compared to unbrowsed trees. Cocoon weight was weakly related to needle C:N ratio, and browsed trees had lower a C:N ratio compared to unbrowsed trees. Needle diâterpene content, known to affect sawfly performance, was neither affected by the browsing treatments nor did it correlate with sawfly weight. 5. We conclude that mammalian herbivory can affect insect herbivore performance, with potential consequences for ecological communities and with particular importance for insect population dynamics. The measured plant variables could not fully explain the effect on sawfly performance providing a starting point for the consideration of additional plant responses induced by mammalian browsing affecting insect performance
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