21 research outputs found
Turbulence in a free surface
We report an experimental and numerical study of turbulent fluid motion in a
free surface. The flow is realized experimentally on the surface of a tank
filled with water stirred by a vertically oscillating grid positioned well
below the surface. Particles floating on the surface are used to visualize the
flow. The effect of surface waves appears to be negligible. The flow is
unconventional in that it is confined to two dimensions but does not have
squared vorticity as a conservation law, that it is not divergence free and
that it inherits scaling features of the mean square velocity differences
S_2(R) and the vorticity fluctuations Omega(R) from the bulk 3-d turbulence.Comment: 4 pages, 4 Postscript figure
Magnitudes of biomarker reductions in response to controlled reductions in cigarettes smoked per day: A one-week clinical confinement study
AbstractTobacco toxicant-related exposure reduction is an important tool in harm reduction. Cigarette per day reduction (CPDR) occurs as smokers migrate from smoking cigarettes to using alternative tobacco/nicotine products, or quit smoking. Few reports characterize the dose–response relationships between CPDR and effects on exposure biomarkers, especially at the low end of CPD exposure (e.g., 5 CPD). We present data on CPDR by characterizing magnitudes of biomarker reductions. We present data from a well-controlled, one-week clinical confinement study in healthy smokers who were switched from smoking 19–25 CPD to smoking 20, 10, 5 or 0 CPD. Biomarkers were measured in blood, plasma, urine, and breath, and included smoke-related toxicants, urine mutagenicity, smoked cigarette filter analyses (mouth level exposure), and vital signs. Many of the biomarkers (e.g., plasma nicotine) showed strong CPDR dose–response reductions, while others (e.g., plasma thiocyanate) showed weaker dose–response reductions. Factors that lead to lower biomarker reductions include non-CPD related contributors to the measured response (e.g., other exposure sources from environment, life style, occupation; inter-individual variability). This study confirms CPDR dose-responsive biomarkers and suggests that a one-week design is appropriate for characterizing exposure reductions when smokers switch from cigarettes to new tobacco products