Development of the Web Users Self-Efficacy scale (WUSE)

The aim of this research was to develop a scale that could evaluate an individuals confidence in using the Internet. Web-based resources are becoming increasingly important within higher education and it is therefore vital that students and staff feel confident and competent in the access, provision, and utilisation of these resources. The scale developed here represents an extension of previous research (Cassidy & Eachus, 2002) that developed a measure of self-efficacy in the context of computer use. An iterative approach was used in the development of the Web User Self-Efficacy scale (WUSE) and the participants were recruited from the student body of a large University in the North West of the United Kingdom, and globally via a web site set up for this purpose. Initial findings suggest that the scale has acceptable standards of reliability and validity though work is continuing to refine the scale and improve the psychometric properties of the tool

Creating and validating self-efficacy scales for students

Purpose: student radiographers must possess certain abilities to progress in their training; these can be assessed in various ways. Bandura’s social cognitive theory identifies self-efficacy as a key psychological construct with regard to how people adapt to environments where new skills are developed. Use of this construct is common in health care literature but little has been noted within radiographic literature. The authors sought to develop a self-efficacy scale for student radiographers. Method: the scale was developed following a standard format. An initial pool of 80 items was generated and psychometric analysis was used to reduce this to 68 items. Radiography students drawn from 7 universities were participants (N=198) in validating the scale. Results: the psychometric properties of the scale were examined using analysis of variance (ANOVA), factor analysis and item analysis. ANOVA demonstrated an acceptable level of known group validity: first-year, second-year, and third-year students all scored significantly differently (P=.035) from one another. Factor analysis identified the most significant factor as confidence in image appraisal. The scale was refined using item and factor analysis to produce the final 25-item scale. Conclusion This is the first published domain-specific self-efficacy scale validated specifically for student radiographers. In its current format it may have pedagogical utility. The authors currently are extending the work to add to the scale’s validity and embedding it into student training to assess its predictive value

Triggering and measuring social inhibitory response in humans immersed in interactions with virtual humans

The aim of the proposed study is to determine if a virtual human can evoke a measurable inhibitory response to anti-social stimuli within the prefrontal cortex. Justification, protocol and demonstrator are described here. The work follows a previous study demonstrating that neural inhibitory responses can be measured within an immersive virtual reality display. We have adopted the approach of combining functional Near Infrared Spectroscopy (fNIRS) and virtual reality head-mounted display. Haemodynamic changes will be measured in healthy participants and subsequently, subjects with mental deficits, as both engage in interactions that seek to evoke a response that would normally be inhibited. Disinhibition is an aspect of social response exaggerated by several deficits of mind, including dementia, autism and Tourette’s syndrome. This research could improve tools for understanding, diagnosis and treatment of such condition

Within- and between-session prefrontal cortex response to virtual reality exposure therapy for acrophobia

Exposure Therapy (ET) has demonstrated its efficacy in the treatment of phobias, anxiety and Post-traumatic Stress Disorder (PTSD), however, it suffers a high drop-out rate because of too low or too high patient engagement in treatment. Virtual Reality Exposure Therapy (VRET) is comparably effective regarding symptom reduction and offers an alternative tool to facilitate engagement for avoidant participants. Neuroimaging studies have demonstrated that both ET and VRET normalize brain activity within a fear circuit. However, previous studies have employed brain imaging technology which restricts people’s movement and hides their body, surroundings and therapist from view. This is at odds with the way engagement is typically controlled. We used a novel combination of neural imaging and VR technology—Functional Near-Infrared Spectroscopy (fNIRS) and Immersive Projection Technology (IPT), to avoid these limitations. Although there are a few studies that have investigated the effect of VRET on a brain function after the treatment, the present study utilized technologies which promote ecological validity to measure brain changes after VRET treatment. Furthermore, there are no studies that have measured brain activity within VRET session. In this study brain activity within the prefrontal cortex (PFC) was measured during three consecutive exposure sessions. N = 13 acrophobic volunteers were asked to walk on a virtual plank with a 6 m drop below. Changes in oxygenated (HbO) hemoglobin concentrations in the PFC were measured in three blocks using fNIRS. Consistent with previous functional magnetic resonance imaging (fMRI) studies, the analysis showed decreased activity in the DLPFC and MPFC during first exposure. The activity increased toward normal across three sessions. The study demonstrates potential efficacy of a method for measuring within-session neural response to virtual stimuli that could be replicated within clinics and research institutes, with equipment better suited to an ET session and at fraction of the cost, when compared to fMRI. This has application in widening access to, and increasing ecological validity of, immersive neuroimaging across understanding, diagnosis, assessment and treatment of, a range of mental disorders such as phobia, anxiety and PTSD or addictions

Rx3 and Shh direct anisotropic growth and specification in the zebrafish tuberal/anterior hypothalamus.

In the developing brain, growth and differentiation are intimately linked. Here we show that in the zebrafish embryo, the homeodomain transcription factor rx3 co-ordinates these processes to build the tuberal/anterior hypothalamus. Analysis of rx3 chk mutant/rx3 morphant fish and EdU pulse-chase studies reveal that rx3 is required to select tuberal/anterior hypothalamic progenitors and to orchestrate their anisotropic growth. In the absence of rx3 function, progenitors accumulate in the 3(rd) ventricular wall, die or are inappropriately-specified, the shh+ anterior recess does not form, and its resident pomc+, ff1b+ and otp+ TH+ cells fail to differentiate. Manipulation of Shh signalling shows that shh co-ordinates progenitor cell selection and behaviour by acting as an on-off switch for rx3 Together our studies show that shh and rx3 govern formation of a distinct progenitor domain that elaborates pattern through its anisotropic growth and differentiation

Population requirement for primary knee replacement surgery: a cross‐sectional study

Objectives. To determine the population requirement for total knee replacement (TKR) in England Methods. Population‐based study using an age/sex‐stratified random sample of 28 080 individuals aged 35 yr and over. Incident disease was estimated from prevalence by statistical modelling. The New Zealand priority criteria for major joint replacement were used for case selection. Results. Patients with knee disease were less likely than those with equally severe hip disease to have been referred to a specialist, to have consulted an orthopaedic surgeon or to be on a waiting list for joint replacement. The estimated annual requirement of TKRs in England, based on New Zealand Scores alone, was 55 800 (95% CI 40 700-70 900), contrasting sharply with an annual provision of 29 300 actually observed. However, in contrast to previously reported hip replacement data, when patient willingness to undergo surgery was considered, this estimate decreased considerably. Conclusions. There appears to be an underprovision of TKR in England. This may be due in part to differences in perception of disease severity and likely response to surgery between patients and general practitioners on one hand, and rheumatologists and orthopaedic surgeons on the othe

The influence of stimuli valence, extraversion, and emotion regulation on visual search within real-world scenes

Affective traits, including extraversion and emotion regulation, are important considerations in clinical psychology due to their associations with the occurrence of affective disorders. Previously, emotional real-world scenes have been shown to influence visual search. However, it is currently unknown whether extraversion and emotion regulation can influence visual search towards neutral targets embedded within real-world scenes, or whether these traits can impact the effect of emotional stimuli on visual search. An opportunity sample of healthy individuals had trait levels of extraversion and emotion regulation recorded before completing a visual search task. Participants more accurately identified search targets in neutral images compared to positive images, whilst response times were slower in negative images. Importantly, individuals with higher trait levels of expressive suppression displayed faster identification of search targets regardless of the emotional valence of the stimuli. Extraversion and cognitive reappraisal did not influence visual search. These findings add to our understanding regarding the influence of extraversion, cognitive reappraisal, and expressive suppression on our ability to allocate attention during visual search when viewing real-world scenes