EPHEDRINE ENHANCES ANALGESIC EFFECT OF MORPHINE

Morphine-ephedrine interaction on analgesia was studied in mice (n = 240) and in post-operative patients (n = 32). It was found that combining morphine and ephedrine enhances analgesia which is not significantly different from the effect of morphine given alone at double dose

Middle Cerebral Artery Infarction Associated with Sildenafil Citrate (Viagra) Use

Introduction: Sildenafil is a phosphodiesterase 5 enzyme inhibitor used in the treatment of erectile dysfunction and pulmonary hypertension. The use of sildenafil with nitrates is well known to cause myocardial ischemia. However, patients with a history of hypotension, arrhythmia, previous myocardial infarction, or stroke should be given sildenafil carefully. A few cases have been reported in the literature related to ischemic stroke and transient ischemic attack due to sildenafil use

Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache

Study Objectives: To investigate the effects of different doses of oral caffeine-paracetamol combinations in postdural puncture headache (PDPH) prophylaxis

Retrospective analysis of burn injuries caused by hot milk in 159 pediatric patients: 14 years of experience in a burn unit

BACKGROUND: The aim of this study was to investigate the hot milk burns among the pediatric patients and to compare our experiences with similar studies in the literature

Pre-emptive efficacy of epidural fentanyl in elective abdominal surgery

Background and aim This study determines whether epidural fentanyl given before incision decreases the requirements for opioid analgesia postoperatively, compared with the same dose of epidural fentanyl given after the surgery

Propofol-ketamine vs propofol-fentanyl combinations for deep sedation and analgesia in pediatric patients undergoing burn dressing changes

background: The aim of this study was to compare propofol-ketamine (PK) and propofol-fentanyl (PF) combinations for deep sedation and analgesia in pediatric burn wound dressing changes