53,392 research outputs found

    The Great Divide: Ruralisation of Poverty in Russia

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    Using data from the RLMS for the period 2000-2004 we investigate poverty trends in Russia. We find that urban poverty declines at twice the rate of rural poverty so that by 2004 poverty in Russia had become a largely rural phenomenon for the first time since transition began. This finding does not stem from changing population characteristics or shares, is not dependent on the use of a particular poverty line nor is it driven by the rapid expansions that have occurred in Moscow, St. Petersburg or other urban areas. Our findings flesh out those of Ravallion et al (2007) who, in contrast to other regions, "find signs" of a ruralisation of poverty in Eastern Europe and the Former Soviet Union. We attribute some of the differential to the labour market

    EGF receptor trafficking: consequences for signaling and cancer

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    The ligand-stimulated epidermal growth factor receptor (EGFR) has been extensively studied in the analysis of molecular mechanisms regulating endocytic traffic and the role of that traffic in signal transduction. Although such studies have largely focused on mitogenic signaling and dysregulated traffic in tumorigenesis, there is growing interest in the potential role of EGFR traffic in cell survival and the consequent response to cancer therapy. Here we review recent advances in our understanding of molecular mechanisms regulating ligand-stimulated EGFR activation, internalization, and post-endocytic sorting. The role of EGFR overexpression/mutation and new modulators of EGFR traffic in cancer and the response to cancer therapeutics are also discussed. Finally, we speculate on the relationship between EGFR traffic and cell survival

    Aspergillosis of the CNS in a pediatric liver transplant recipient: Case report and review

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    A 2-month-old infant who had undergone orthotopic liver transplantation at the age of 2 weeks for carbamoyl phosphate synthetase deficiency developed infection of the CNS due to Aspergillus fumigatus. The patient was successfully treated with administration of a combination of antifungal agents (including intraventricular amphotericin B), drainage of the parietal lobe abscess, and cessation of immunosuppression. An intraventricular catheter was used both to obtain ventricular fluid for microbiologic testing and to deliver amphotericin B during nearly 4 months of treatment. We review literature on aspergillosis in solid-organ transplant recipients, especially those in whom the disease involves the CNS, and discuss in particular clinical presentation, diagnosis, treatment, and outcome

    Tunable Hydrogen Storage in Magnesium - Transition Metal Compounds

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    Magnesium dihydride (\mgh) stores 7.7 weight % hydrogen, but it suffers from a high thermodynamic stability and slow (de)hydrogenation kinetics. Alloying Mg with lightweight transition metals (TM = Sc, Ti, V, Cr) aims at improving the thermodynamic and kinetic properties. We study the structure and stability of Mgx_xTM1x_{1-x}H2_2 compounds, x=[0x=[0-1], by first-principles calculations at the level of density functional theory. We find that the experimentally observed sharp decrease in hydrogenation rates for x0.8x\gtrsim0.8 correlates with a phase transition of Mgx_xTM1x_{1-x}H2_2 from a fluorite to a rutile phase. The stability of these compounds decreases along the series Sc, Ti, V, Cr. Varying the transition metal (TM) and the composition xx, the formation enthalpy of Mgx_xTM1x_{1-x}H2_2 can be tuned over the substantial range 0-2 eV/f.u. Assuming however that the alloy Mgx_xTM1x_{1-x} does not decompose upon dehydrogenation, the enthalpy associated with reversible hydrogenation of compounds with a high magnesium content (x=0.75x=0.75) is close to that of pure Mg.Comment: 8 pages, 5 figure

    ENGINE PERFORMANCE ON ATOMIZATION OF FUEL INJECTOR: A REVIEW

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    The impact of the fuel injection of fuel atoms on engine performance has been investigated to improve fuel efficiency and waste disposal features. The fuel swirl method for injection atomization was evaluated both by the analysis of the fuel flow and the sample test. The goal of the paper is to establish good fuel atomization over the range of engine performance. As a result of our studies, it has been concluded that the desired atomization can be achieved when gasoline is thrown into a circular motion. Fuel spray and atomization features play an important role in the performance of internal combustion engines. An atomization study to evaluate the numerical fuel injection used in the IGC (Inner Guide-vane Combustor) under various combination and performance conditions has been performed to determine the suspension of the proposed fuel injection to be used in the IGC. Additional results have shown that a single-hole fuel injection, forward injection direction, and a splash of

    Some Greek Legal Papyri from the Michigan Collection

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    The documents which form the subject of this paper are part of the Michigan Collection of Papyri recently acquired by Professor F. W. Kelsey in Egypt and secured for the University by the generosity of the Regents and certain friends and alumni, among the latter Mr. J. W. Anderson, of the Law Class of 189o. A large proportion of these documents are of a legal nature, and from these I have selected for translation four, which may be regarded as typical specimens of their respective classes

    Weakly nonlinear subcritical instability of visco-elastic Poiseuille flow

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    It is well known that the Poiseuille flow of a visco-elastic polymer fluid between plates or through a tube is linearly stable in the zero Reynolds number limit, although the stability is weak for large Weissenberg numbers. In this paper we argue that recent experimental and theoretical work on the instability of visco-elastic fluids in Taylor-Couette cells and numerical work on channel flows suggest a scenario in which Poiseuille flow of visco-elastic polymer fluids exhibits a nonlinear "subcritical" instability due to normal stress effects, with a threshold which decreases for increasing Weissenberg number. This proposal is confirmed by an explicit weakly nonlinear stability analysis for Poiseuille flow of an UCM fluid. Our analysis yields explicit predictions for the critical amplitude of velocity perturbations beyond which the flow is nonlinearly unstable, and for the wavelength of the mode whose critical amplitude is smallest. The nonlinear instability sets in quite abruptly at Weissenberg numbers around 4 in the planar case and about 5.2 in the cylindrical case, so that for Weissenberg numbers somewhat larger than these values perturbations of the order of a few percent in the wall shear stress suffice to make the flow unstable. We have suggested elsewhere that this nonlinear instability could be an important intrinsic route to melt fracture and that preliminary experiments are both qualitatively and quantitatively in good agreement with these predictions.Comment: 20 pages, 16 figures. Accepted for publication in J. of Non-Newtonian Fluid Mechanic
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