98 research outputs found
Autoimmune gastrointestinal complications in patients with Systemic Lupus Erythematosus: case series and literature review
- Author
- Agmon-Levin N
- Ahmed QM
- Akram S
- Arnett FC
- Bessone F
- Breuer GS
- Byun JY
- Cabrera GE
- Carmona-Fernandes D
- Carone FA
- Chebli JM
- Chong WP
- Chowdhary VR
- Cortese AF
- Cowling DC
- CriĆ cov GI
- Culp KS
- D A Isenberg
- De Jager PL
- Denham JM
- Dreiling DA
- Dubois EL
- Ebert EC
- Efe C
- Efe C
- Einarsdottir E
- Essaadouni L
- FernĂĄndez RodrĂguez AM
- Ferreiros-Vidal I
- Fina D
- Floreani A
- Freeman HJ
- Gershwin ME
- Gibson T
- Grimbacher B
- Gupta D
- Hallegua DS
- Hamed I
- Han S
- Harada K
- Hennes EM
- Her M
- Homberg JC
- Irving KS
- Isenberg DA
- Janssens P
- Joske RA
- Ju JH
- Kapila N
- Katsanos KH
- Katsanos KH
- Laing TJ
- Lee C-K
- Leggett BA
- Leonard WJ
- Levy C
- Lohse AW
- Ludvigsson JF
- Mackay IR
- Makol A
- Matsumoto T
- Medina F
- Michalopoulos G
- Miller MH
- Miyazaki T
- Muratori P
- Nakou M
- Nesher G
- Netto AP
- Nitzan O
- Park SW
- Pascual-Ramos V
- Pisetsky DS
- Pollak VE
- Reifenstein EC
- Rensch MJ
- Reynolds JC
- Rodriguez EA
- Runyon BA
- Rustgi AK
- S CustĂłdio Alves
- S Fasano
- Seelig R
- Serrano LĂłpez MC
- Shapeero LG
- Shizuma T
- Shizuma T
- Sparberg M
- Steffan W
- Sultan SM
- SĂĄnchez-Guerrero J
- Takahashi A
- Taourel P
- Thomas JR
- Tian X-P
- van Hoek B
- Vergani D
- Vitali C
- Yamashita H
- Zheng R-H
- Zizic TM
- Zizic TM
- Publication venue
- Publication date
- 01/01/2016
- Field of study
The association of systemic lupus erythematosus (SLE) with gastrointestinal autoimmune diseases is rare, but has been described in the literature, mostly as case reports. However, some of these diseases may be very severe, thus a correct and early diagnosis with appropriate management are fundamental. We have analysed our data from the SLE patient cohort at University College Hospital London, established in 1978, identifying those patients with an associated autoimmune gastrointestinal disease. We have also undertaken a review of the literature describing the major autoimmune gastrointestinal pathologies which may be coincident with SLE, focusing on the incidence, clinical and laboratory (particularly antibody) findings, common aetiopathogenesis and complications
Perspectives on utilization of edible coatings and nano-laminate coatings for extension of postharvest storage of fruits and vegetables
- Author
- A Acevedo-Fani
- A Bailey
- A Hambleton
- A Perdones
- A Synowiec
- AC Pinheiro
- AE Pavlath
- AM Lima
- AntĂłnio A. Vicente
- BGS Medeiros
- BGS Medeiros
- BWS Souza
- C Barry-Ryan
- C Fagundes
- C Mohamed
- C PĂ©rez-PĂ©rez
- C Ribeiro
- C Valenzuela
- CJ Wijesinghe
- D Chandler
- D Eshel
- D Hung Van
- D Jasso de RodrĂguez
- D Lin
- D Paladines
- D Spadaro
- Diana Jasso de RodrĂguez
- DM Costa De
- E Ayrancy
- E Bosquez-Molina
- E Lugo-Medina
- EA Baldwin
- EM Yahia
- F Castillo
- F Debeaufort
- G Galietta
- G Galietta
- GI Olivas
- H Dou
- HA Ruiz
- HI Labouta
- HM Hamzah
- IF James
- IH Kim
- IM Brasil
- J Bai
- J Calvo
- J Giovannoni
- J Gustavsson
- J Weiss
- JB Schlenoff
- JJ Kester
- JJ Villaverde
- JM Valverde
- JT Martins
- K Recep
- KL Mittal
- KS Miller
- L Kitinoja
- L Salvia-Trujillo
- L Schena
- L SĂĄnchez-GonzĂĄlez
- M Ahmad
- M Chiumarelli
- M Granda-Valdés
- M Kurek
- M Maqbool
- M Mari
- MA Cerqueira
- MA Cerqueira
- MA Cerqueira
- MA Garcia
- MA Garcia
- MA Gatto
- MA Nobile Del
- MA Rojas-GraĂŒ
- MarĂa L. Flores-LĂłpez
- MB Perez-Gago
- MG Carneiro-da-Cunha
- Miguel A. Cerqueira
- MJ Fabra
- ML Ramos-GarcĂa
- MP Souza
- MR Moreira
- MS Tapia
- N Mantilla
- NE Suyatma
- OL Ramos
- P Bergo
- P Fajardo
- P Hernåndez-Muñoz
- P Hong
- P Tripathi
- P Zimet
- Q Li
- R Kotan
- R Sothornvita
- RD Hagenmaier
- RE Henriod
- RJ Avena-Bustillos
- RJ Zhang
- RK Dhall
- RM Raybaudi-Massilia
- S Ben-Yehoshua
- S Droby
- S Droby
- S Galus
- S Galus
- S Neethirajan
- SA Valencia-Chamorro
- SC Datta
- SG Jang
- T Bourtoom
- T Bourtoom
- TA Trezza
- TG McCollum
- TP Cañamås
- United States Food and Drug Administration (US FDA)
- V Falguera
- V Hershko
- WT Xu
- Y Qin
- Y Zhao
- YA Batta
- Z Tietel
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/09/2016
- Field of study
It is known that in developing countries, a large quantity of fruit and vegetable losses results at postharvest and processing stages due to poor or scarce storage technology and mishandling during harvest. The use of new and innovative technologies for reducing postharvest losses is a requirement that has not been fully covered. The use of edible coatings (mainly based on biopolymers) as a postharvest technique for agricultural commodities has offered biodegradable alternatives in order to solve problems (e.g., microbiological growth) during produce storage. However, biopolymer-based coatings can present some disadvantages such as: poor mechanical properties (e.g., lipids) or poor water vapor barrier properties (e.g., polysaccharides), thus requiring the development of new alternatives to solve these drawbacks. Recently, nanotechnology has emerged as a promising tool in the food processing industry, providing new insights about postharvest technologies on produce storage. Nanotechnological approaches can contribute through the design of functional packing materials with lower amounts of bioactive ingredients, better gas and mechanical properties and with reduced impact on the sensorial qualities of the fruits and vegetables. This work reviews some of the main factors involved in postharvest losses and new technologies for extension of postharvest storage of fruits and vegetables, focused on perspective uses of edible coatings and nano-laminate coatings.MarĂa L. Flores-LĂłpez thanks Mexican Science and Technology Council (CONACYT, Mexico) for PhD fellowship support (CONACYT Grant Number: 215499/310847). Miguel A. Cerqueira (SFRH/BPD/72753/2010) is recipient of a fellowship from the Fundação para a CiĂȘncia e Tecnologia (FCT, POPH-QREN and FSE Portugal). The authors also thank the FCT Strategic Project of UID/ BIO/04469/2013 unit, the project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and the project ââBioInd Biotechnology and Bioengineering for improved Industrial and AgroFood processes,ââ REF. NORTE-07-0124-FEDER-000028 Co-funded by the Programa Operacional Regional do Norte (ON.2 â O Novo Norte), QREN, FEDER. Fundação Cearense de Apoio ao Desenvolvimento CientĂïŹco e TecnolĂłgico â FUNCAP, CE Brazil (CI10080-00055.01.00/13)
Applications of lignin in the agri-food industry
- Author
- A Agarwal
- A Barapatre
- A GarcĂa
- A RodrĂguez
- A Salanti
- AJ Ragauskas
- AMA Nada
- AN Begum
- B Baurhoo
- BH Monien
- BL Henry
- BM Upton
- BO Abo
- C AwungachaLekelefac
- C Crestini
- C Frangville
- C Huang
- C Pouteau
- C Pouteau
- CA Cateto
- CM Fierro
- CP Xu
- D Barana
- D Kai
- D Ro
- D Stewart
- DH Nagaraju
- E Lee
- E Slavikova
- EM Fernandes
- F Chen
- F Zamboni
- F Zhang
- FJ Lu
- FM Pereira
- G Andrei
- G Jaganathan
- H Faustino
- H Nakashima
- H Priefert
- H Sadeghifar
- H Sakagami
- H Sakagami
- H Wang
- H Wu
- HM Lou
- HM Lou
- I Calgeris
- I Korbag
- I Spiridon
- J Sunthornvarabhas
- J Wang
- J Wang
- J Zemek
- J Zhang
- J Zhang
- JB Lee
- JC Vengal
- JDC Medina
- JH Lora
- JJ Meister
- JL Espinoza-Acosta
- JM Cruz
- JS Kim
- JS Lupoi
- K Gabov
- K Matsuhisa
- K Satoh
- L Hui
- L Klapiszewski
- L Paszner
- L Qu
- L Shi
- L Siddiqui
- L Zhu
- LRC Barclay
- LY Stephen
- M Azadfar
- M Mitjans
- M Nar
- M Tortora
- M Zimniewska
- M Zimniewska
- MB Marulasiddeshwara
- MP Vinardell
- MV Galkin
- MY Zhang
- N Hasnaoui
- P Figueiredo
- P Figueiredo
- P Figueiredo
- PK Mishra
- Q Wang
- R Curvello
- R Gyawali
- R Kaur
- R NĂșñez-Flores
- R Pucciariello
- R Rinaldi
- R Wang
- R Whetten
- RR Sederoff
- S Baumberger
- S Kubo
- S Ou
- S Sato
- SC Lee
- SD Mansfield
- SE Salamouny
- SE Salamouny
- SM Ojagh
- T Dizhbite
- T Norikura
- V Ugartondo
- VI Popaa
- VK Thakur
- W Jonglertjunya
- W Schutyser
- W Yang
- WC Browning
- WJ Mulder
- WK El-Zawawy
- WOS Doherty
- X Dong
- X Luo
- X Pan
- X Wang
- XY Du
- Y Chen
- Y Hasegawa
- Y Peng
- Y Qian
- Y Song
- Y Zhou
- Z Li
- Z Peng
- ZW He
- Publication venue
- Springer, Cham
- Publication date
- 01/01/2019
- Field of study
Of late, valorization of agri-food industrial by-products and their sustainable utilization is
gaining much contemplation world-over. Globally, 'Zero Waste Concept' is promoted with
main emphasis laid towards generation of minimal wastes and maximal utilization of plantbased
agri-food raw materials. One of the wastes/by-products in the agri-food industry are the
lignin, which occurs as lignocellulosic biomass. This biomass is deliberated to be an
environmental pollutant as they offer resistance to natural biodegradation. Safe disposal of this
biomass is often considered a major challenge, especially in low-income countries. Hence, the
application of modern technologies to effectively reduce these types of wastes and maximize
their potential use/applications is vital in the present day scenario. Nevertheless, in some of the
high-income countries, attempts have been made to efficiently utilize lignin as a source of fuel, as a raw material in the paper industry, as a filler material in biopolymer based packaging and
for producing bioethanol. However, as of today, agri-food industrial applications remains
significantly underexplored. Chemically, lignin is heterogeneous, bio-polymeric, polyphenolic
compound, which is present naturally in plants, providing mechanical strength and rigidity.
Reports are available wherein purified lignin is established to possess therapeutic values; and
are rich in antioxidant, anti-microbial, anti-carcinogenic, antidiabetic properties, etc.
This chapter is divided into four sub-categories focusing on various technological
aspects related to isolation and characterization of lignin; established uses of lignin; proved
bioactivities and therapeutic potentials of lignin, and finally on identifying the existing research
gaps followed by future recommendations for potential use from agri-food industrial wastes.Theme of this chapter is based on our ongoing project- Valortech,
which has received funding from the European Unionâs Horizon 2020 research and innovation
program under grant agreement No 810630
The incidence of cardiovascular events after hospitalization due to CAP and their association with different inflammatory markers
- Author
- A Craig
- A El Solh
- A Kudva
- A Torres
- Ana DĂaz LĂłpez
- Belén Arnalich
- Carmen SuĂĄrez
- D Viasus
- DG Remick
- DM Musher
- E Calbo
- E Demerath
- EB Milbrandt
- EM Mortensen
- EM Shevach
- FL Brancati
- Francisco RodrĂguez Salvanes
- G De Backer
- G Stoll
- Guillermo Fernåndez Jiménez
- GW Waterer
- H Jasti
- Hortensia de la Fuente
- J Adamuz
- J Bordon
- J Bordon
- J Johnstone
- J Ramirez
- JA Kellum
- Javier Aspa
- JK Kolls
- José Curbelo
- JosĂ© MarĂa GalvĂĄn RomĂĄn
- Julio Ancochea
- K Ley
- L Smeeth
- Lorena Vega Piris
- M Christ-Crain
- M Madjid
- Mara Ortega-GĂłmez
- ME Charlson
- MJ Fine
- MO Li
- MS Paats
- MS Paats
- N Soto-Gomez
- Olga Rajas
- P Peyrani
- P Ramirez
- P Schuetz
- PM Ridker
- R Fernandez-Botran
- R Martinez
- R Menendez
- RD Riley
- RG Wunderink
- S Bello
- S Ewig
- S Kruger
- S Kruger
- S Kruger
- S Kruger
- S Kruger
- S Yende
- S Yende
- S Yende
- Sergio Luquero Bueno
- T Korn
- T Welte
- TW Perry
- VF Corrales-Medina
- VF Corrales-Medina
- VF Corrales-Medina
- VF Corrales-Medina
- World Health Organization
- WS Lim
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Immune response pattern in recurrent Plasmodium vivax malaria
- Author
- A GuimarĂŁes da Costa
- A Mahanta
- A Ratcliff
- Adriana Malheiro
- AJ RodrĂguez-Morales
- AL Silva
- Allyson GuimarĂŁes da Costa
- AM Siqueira
- Andréa Teixeira-Carvalho
- AP Freitas do Rosario
- AP Freitas do Rosario
- AR Hasugian
- AT Baldé
- BB Andrade
- BD Akanmori
- BM Greenwood
- BM Greenwood
- C Claser
- Claudio Romero Farias Marinho
- CQ Nie
- CR Engwerda
- CS Limaye
- D Kassa
- DC Mabey
- DF Fiorentino
- DK Kochar
- DS Hansen
- E Belnoue
- E Tjitra
- EC Duarte
- EK Riccio
- EM Riley
- EN Takem
- FG Versiani
- FT Costa
- G Snounou
- GR Awab
- HC Coelho
- I Mueller
- I Safeukui
- IF Cook
- IM Lisse
- J Langhorne
- J Oliveira-Ferreira
- J Wipasa
- JK Baird
- JK Baird
- JL Baptista
- Jordana Grazziela Coelho-dos-Reis
- K Jangpatarapongsa
- K Jangpatarapongsa
- KN Couper
- L Huldén
- L Hviid
- L Schofield
- M Ho
- M Imwong
- M Walther
- MA Alexandre
- Marcelo LuĂs Monteiro Pereira
- Marcus VinĂcius GuimarĂŁes de Lacerda
- MB Markus
- MV Lacerda
- MV Lacerda
- MVG Lacerda
- ND Karunaweera
- NJ White
- NJ White
- NM Anstey
- NS Hojo-Souza
- Olindo Assis Martins-Filho
- PatrĂcia Puccinelli Orlandi
- Paulo Afonso Nogueira
- PW Gething
- QI Borges
- R Astier
- R Goonewardene
- RM Braz
- RM Gonçalves
- RM Gonçalves
- RN Bronzan
- RN Price
- RN Rodrigues-da-Silva
- RS Pedro
- S Chuangchaiya
- S Worku
- S Yeung
- SN Wickramasinghe
- T Ketema
- T Were
- TR Mosmann
- TS Medina
- VR Mendonça
- WA Williamson
- Wuelton Marcelo Monteiro
- Y Belkaid
- YG Kwak
- Yury Oliveira Chaves
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Approaches in biotechnological applications of natural polymers
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2016
- Field of study
Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento CientfĂico e TecnolĂłgico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de NvĂel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)
Search for strongly interacting massive particles generating trackless jets in proton-proton collisions at s = 13 TeV
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- Ălvarez FernĂĄndez A
- Ăsterberg K
- Ăzçelik Ă
- Ć irokĂœ J
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
A search for dark matter in the form of strongly interacting massive particles (SIMPs) using the CMS detector at the LHC is presented. The SIMPs would be produced in pairs that manifest themselves as pairs of jets without tracks. The energy fraction of jets carried by charged particles is used as a key discriminator to suppress efficiently the large multijet background, and the remaining background is estimated directly from data. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 16.1 fb - 1 , collected with the CMS detector in 2016. No significant excess of events is observed above the expected background. For the simplified dark matter model under consideration, SIMPs with masses up to 100 GeV are excluded and further sensitivity is explored towards higher masses
Evidence for Top Quark Production in Nucleus-Nucleus Collisions
- Author
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- Aarup Petersen H
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- Zorbilmez C
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- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Ălvarez FernĂĄndez A
- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Peer reviewe
Observation of the B-s(0) -> X(3872)phi Decay
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
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- Attikis A
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- Capiluppi P
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- Carrillo Montoya CA
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- Chernyavskaya N
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- Civinini C
- Claes DR
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- CMS Collaboration
- Cockerill DJA
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- Cornelis T
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- 01/01/2020
- Field of study
Using a data sample of proton-proton collisions at root s = 13 TeV, corresponding to an integrated luminosity of 140 fb(-1) collected by the CMS experiment in 2016-2018, the B-s(0) -> X(3872)phi decay is observed. Decays into J/psi pi(+)pi(-) and K+K- are used to reconstruct, respectively, the X(3872) and phi. The ratio of the product of branching fractions B[B-s(0) -> X(3872)phi]B[X(3872) -> J/psi pi(+)pi(-)] to the product B[B-s(0) ->psi(2S)phi]B[psi(2S) -> J/psi pi(+)pi(-)] is measured to be [2.21 +/- 0.29(stat) +/- 0.17(syst)]%. The ratio B[B-s(0) -> X(3872)phi]/B[B-0 -> X(3872)K-0] is found to be consistent with one, while the ratio B[B-s(0) -> X(3872)phi]/B[B+-> X(3872)K+] is two times smaller. This suggests a difference in the production dynamics of the X(3872) in B-0 and B(0)s meson decays compared to B+. The reported observation may shed new light on the nature of the X(3872) particle.Peer reviewe
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- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
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- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
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