473 research outputs found

    ACTUALIDADES: Aspectos quirĂșrgicos del ulcus gastroduodenal

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    CD-ROM publication of the Mars digital cartographic data base

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    The recently completed Mars mosaicked digital image model (MDIM) and the soon-to-be-completed Mars digital terrain model (DTM) are being transcribed to optical disks to simplify distribution to planetary investigators. These models, completed in FY 1991, provide a cartographic base to which all existing Mars data can be registered. The digital image map of Mars is a cartographic extension of a set of compact disk read-only memory (CD-ROM) volumes containing individual Viking Orbiter images now being released. The data in these volumes are pristine in the sense that they were processed only to the extent required to view them as images. They contain the artifacts and the radiometric, geometric, and photometric characteristics of the raw data transmitted by the spacecraft. This new set of volumes, on the other hand, contains cartographic compilations made by processing the raw images to reduce radiometric and geometric distortions and to form geodetically controlled MDIM's. It also contains digitized versions of an airbrushed map of Mars as well as a listing of all feature names approved by the International Astronomical Union. In addition, special geodetic and photogrammetric processing has been performed to derive rasters of topographic data, or DTM's. The latter have a format similar to that of MDIM, except that elevation values are used in the array instead of image brightness values. The set consists of seven volumes: (1) Vastitas Borealis Region of Mars; (2) Xanthe Terra of Mars; (3) Amazonis Planitia Region of Mars; (4) Elysium Planitia Region of Mars; (5) Arabia Terra of Mars; (6) Planum Australe Region of Mars; and (7) a digital topographic map of Mars

    The complete management of extremity vascular injury in a local population: A wartime report from the 332nd Expeditionary Medical Group/Air Force Theater Hospital, Balad Air Base, Iraq

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    Background: Although the management of vascular injury in coalition forces during Operation Iraqi Freedom has been described, there are no reports on the in-theater treatment of wartime vascular injury in the local population. This study reports the complete management of extremity vascular injury in a local wartime population and illustrates the unique aspects of this cohort and management strategy. Methods: From September 1, 2004, to August 31, 2006, all vascular injuries treated at the Air Force Theater Hospital (AFTH) in Balad, Iraq, were registered. Those in non-coalition troops were identified and retrospectively reviewed. Results: During the study period, 192 major vascular injuries were treated in the local population in the following distribution: extremity 70% (n = 134), neck and great vessel 17% (n = 33), and thoracoabdominal 13% (n = 25). For the extremity cohort, the age range was 4 to 68 years and included 12 pediatric injuries. Autologous vein was the conduit of choice for these vascular reconstructions. A strict wound management strategy providing repeat operative washout and application of the closed negative pressure adjunct was used. Delayed primary closure or secondary coverage with a split-thickness skin graft was required in 57% of extremity wounds. All patients in this cohort remained at the theater hospital through definitive wound healing, with an average length of stay of 15 days (median 11 days). Patients required an average of 3.3 operations (median 3) from the initial injury to definitive wound closure. Major complications in extremity vascular patients, including mortality, were present in 15.7% (n = 21). Surgical wound infection occurred in 3.7% (n = 5), and acute anastomotic disruption in 3% (n = 4). Graft thrombosis occurred in 4.5% (n = 6), and early amputation and mortality rates during the study period were 3.0% (n = 4) and 1.5% (n = 2), respectively. Conclusions: To our knowledge, this study represents the first large report of wartime extremity vascular injury management in a local population. These injuries present unique challenges related to complex wounds that require their complete management to occur in-theater. Vascular reconstruction using vein, combined with a strict wound management strategy, results in successful limb salvage with remarkably low infection, amputation and mortality rates

    Elevating the impact of conservation physiology by building a community devoted to excellence, transparency, ethics, integrity and mutual respect

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    [Extract] Ten years ago, the journal Conservation Physiology was launched jointly by the Society for Experimental Biology and Oxford University Press. Much has been accomplished since 2012 including publishing over 600 papers in the journal and helping to build a sense of place for aspiring and practicing conservation physiologists (Cooke et al., 2020). Yet, more work is needed to further elevate the impact of conservation physiology as a discipline and community. Here, we summarize what is needed to build and strengthen a community devoted to not only excellence, transparency, ethics, integrity and mutual respect, but also courage to tackle some of the overarching challenges humanity faces. As active voices in the conservation physiology community we hope that this paper will help shape the future of our discipline while also guiding the activities and priorities of the journal and editorial team. Since the term ‘conservation physiology’ was coined by Wikelski and Cooke (2006) it has emerged as an essential component of conservation science and practice. Conservation physiology is about the use of physiological tools, knowledge and concepts to understand and solve conservation problems across diverse taxa (Cooke et al., 2013). It is regarded as being particularly effective at understanding mechanisms, generating cause–effect relationships (e.g. threat X does Y to organism Z), creating predictive tools and testing conservation interventions (Cooke and O’Connor, 2010). Issues relevant to conservation physiology range from very local, focused on recovery of an imperilled population (Birnie-Gauvin et al., 2017), to global-scale issues such as tackling the UN Sustainable Development Goals (Cooke et al., 2020) and the climate crisis (Madliger et al., 2021c). The discipline is now supported by a conceptual framework (Coristine et al., 2014), a journal (https://academic.oup.com/conphys) and a reference book (Madliger et al. 2021a). There is also a growing community of researchers who engage in conservation physiology and even define themselves as conservation physiologists (Madliger et al., 2021b). Moreover, in conservation physiology there are success stories that demonstrate the potential of conservation physiology (Madliger et al., 2016)

    A brain-infecting parasite impacts host metabolism both during exposure and after infection is established

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    Metabolic costs associated with parasites should not be limited to established infections. Even during initial exposure to questing and attacking parasites, hosts can enact behavioural and physiological responses that could also incur metabolic costs. However, few studies have measured these costs directly. Hence, little is known about metabolic costs arising from parasite exposure. Furthermore, no one has yet measured whether and how previous infection history modulates metabolic responses to parasite exposure. Here, using the California killifish Fundulus parvipinnis and its brain‐infecting parasite Euhaplorchis californiensis, we quantified how killifish metabolism, behaviour and osmoregulatory phenotype changed upon acute exposure to parasite infectious stages (i.e. cercariae), and with long‐term infection. Exposure to cercariae caused both naïve and long‐term infected killifish to acutely increase their metabolic rate and activity, indicating detection and response to parasite infectious stages. Additionally, these metabolic and behavioural effects were moderately stronger in long‐term infected hosts than naïve killifish, suggesting that hosts may develop learned behavioural responses, nociceptor sensitization and/or acute immune mechanisms to limit new infections. Although established infection altered the metabolic response to parasite exposure, established infection did not alter standard metabolic rate, routine metabolic rate, maximum metabolic rate, aerobic scope or citrate synthase enzyme activity. Unexpectedly, established infection reduced lactate dehydrogenase enzyme activity in killifish brains and relative Na+/K+‐ATPase abundance in gills, suggesting novel mechanisms by which E. californiensis may alter its hosts\u27 behaviour and osmoregulation. Thus, we provide empirical evidence that parasites can disrupt the metabolism of their host both during parasite exposure and after infection is established. This response may be modulated by previous infection history, with probable knock‐on effects for host performance, brain energy metabolism, osmoregulation and ecology. A free Plain Language Summary can be found within the Supporting Information of this article

    Geology of the Victoria quadrangle (H02), Mercury

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    Mercury’s quadrangle H02 ‘Victoria’ is located in the planet’s northern hemisphere and lies between latitudes 22.5° N and 65° N, and between longitudes 270° E and 360° E. This quadrangle covers 6.5% of the planet’s surface with a total area of almost 5 million km2. Our 1:3,000,000-scale geologic map of the quadrangle was produced by photo-interpretation of remotely sensed orbital images captured by the MESSENGER spacecraft. Geologic contacts were drawn between 1:300,000 and 1:600,000 mapping scale and constitute the boundaries of intercrater, intermediate and smooth plains units; in addition, three morpho-stratigraphic classes of craters larger than 20 km were mapped. The geologic map reveals that this area is dominated by Intercrater Plains encompassing some almost-coeval, probably younger, Intermediate Plains patches and interrupted to the north-west, north-east and east by the Calorian Northern Smooth Plains. This map represents the first complete geologic survey of the Victoria quadrangle at this scale, and an improvement of the existing 1:5,000,000 Mariner 10-based map, which covers only 36% of the quadrangle

    The relationship between quality of life and compliance to a brace protocol in adolescents with idiopathic scoliosis: a comparative study

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    <p>Abstract</p> <p>Background</p> <p>Corrective bracing for adolescent idiopathic scoliosis (AIS) has favourable outcomes when patients are compliant. However, bracing may be a stressful and traumatic experience and compliance with a bracing protocol is likely to be dependent upon patients' physical, emotional and social wellbeing. The Brace Questionnaire (BrQ), a recently-developed, condition-specific tool to measure quality of life (QOL) has enabled clinicians to study relationships between QOL and compliance.</p> <p>Methods</p> <p>The BrQ was administered to 31 AIS patients after a minimum of 1 year of wearing a brace. Subjects were 13–16 year old South African girls with Cobb angles of 25–40 degrees. Participants were divided into two groups according to their level of compliance with the bracing protocol. Brace Questionnaire sub- and total scores were compared between the two groups using the t-test for comparison of means.</p> <p>Results</p> <p>Twenty participants were classified as compliant and 11 as non-compliant. Mean total BrQ scores (expressed as a percentage) were 83.7 for the compliant group and 64.4 for the non-compliant group (p < 0.001), and on analysis of the 8 domains that make up the BrQ, the compliant group scored significantly higher in the 6 domains that measured vitality and social, emotional and physical functioning.</p> <p>Conclusion</p> <p>Poor compliance with a brace protocol is associated with poorer QOL, with non-compliant patients lacking vitality and functioning poorly physically, emotionally and socially. Quality of life for adolescents with idiopathic scoliosis may relate more to psychosocial coping mechanisms than to physical deformity and its consequences. It is important to establish whether remedial programmes are capable of addressing personal, group and family issues, improving QOL and promoting compliance.</p
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