Transition in Hypersonic Boundary Layers: Role of Dilatational Waves

Transition and turbulence production in a hypersonic boundary layer is investigated in a Mach 6 quiet wind tunnel using Rayleigh-scattering visualization, fast-response pressure measurements, and particle image velocimetry. It is found that the second instability acoustic mode is the key modulator of the transition process. The second mode experiences a rapid growth and a very fast annihilation due to the effect of bulk viscosity. The second mode interacts strongly with the first vorticity mode to directly promote a fast growth of the latter and leads to immediate transition to turbulence.Comment: 5 pages, 6 figure

Signatures of unresolved binaries in stellar spectra: implications for spectral fitting

The observable spectrum of an unresolved binary star system is a superposition of two single-star spectra. Even without a detectable velocity offset between the two stellar components, the combined spectrum of a binary system is in general different from that of either component, and fitting it with single-star models may yield inaccurate stellar parameters and abundances. We perform simple experiments with synthetic spectra to investigate the effect of unresolved main-sequence binaries on spectral fitting, modeling spectra similar to those collected by the APOGEE, GALAH, and LAMOST surveys. We find that fitting unresolved binaries with single-star models introduces systematic biases in the derived stellar parameters and abundances that are modest but certainly not negligible, with typical systematic errors of $300\,\rm K$ in $T_{\rm eff}$, 0.1 dex in $\log g$, and 0.1 dex in $[\rm Fe/H]$ for APOGEE-like spectra of solar-type stars. These biases are smaller for spectra at optical wavelengths than in the near-infrared. We show that biases can be corrected by fitting spectra with a binary model, which adds only two labels to the fit and includes single-star models as a special case. Our model provides a promising new method to constrain the Galactic binary population, including systems with single-epoch spectra and no detectable velocity offset between the two stars.Comment: Accept to MNRAS with minor revisions since v1. 7 pages, 5 figure

Performance Measures to Assess Resiliency and Efficiency of Transit Systems

Transit agencies are interested in assessing the short-, mid-, and long-term performance of infrastructure with the objective of enhancing resiliency and efficiency. This report addresses three distinct aspects of New Jersey’s Transit System: 1) resiliency of bridge infrastructure, 2) resiliency of public transit systems, and 3) efficiency of transit systems with an emphasis on paratransit service. This project proposed a conceptual framework to assess the performance and resiliency for bridge structures in a transit network before and after disasters utilizing structural health monitoring (SHM), finite element (FE) modeling and remote sensing using Interferometric Synthetic Aperture Radar (InSAR). The public transit systems in NY/NJ were analyzed based on their vulnerability, resiliency, and efficiency in recovery following a major natural disaster

Discovery and Characterization of 3000+ Main-Sequence Binaries from APOGEE Spectra

We develop a data-driven spectral model for identifying and characterizing spatially unresolved multiple-star systems and apply it to APOGEE DR13 spectra of main-sequence stars. Binaries and triples are identified as targets whose spectra can be significantly better fit by a superposition of two or three model spectra, drawn from the same isochrone, than any single-star model. From an initial sample of $\sim$20,000 main-sequence targets, we identify $\sim$2,500 binaries in which both the primary and secondary star contribute detectably to the spectrum, simultaneously fitting for the velocities and stellar parameters of both components. We additionally identify and fit $\sim$200 triple systems, as well as $\sim$700 velocity-variable systems in which the secondary does not contribute detectably to the spectrum. Our model simplifies the process of simultaneously fitting single- or multi-epoch spectra with composite models and does not depend on a velocity offset between the two components of a binary, making it sensitive to traditionally undetectable systems with periods of hundreds or thousands of years. In agreement with conventional expectations, almost all the spectrally-identified binaries with measured parallaxes fall above the main sequence in the color-magnitude diagram. We find excellent agreement between spectrally and dynamically inferred mass ratios for the $\sim$600 binaries in which a dynamical mass ratio can be measured from multi-epoch radial velocities. We obtain full orbital solutions for 64 systems, including 14 close binaries within hierarchical triples. We make available catalogs of stellar parameters, abundances, mass ratios, and orbital parameters.Comment: Accepted to MNRAS with minor revisions since v1. 19 pages, 12 figures, plus Appendice

Sensitivity Analysis on the Sizing Parameters of a Series-Parallel HEV

AAC 2019, 9th IFAC Symposium on Advances in Automotive Control, ORLEANS, FRANCE, 23-/06/2019 - 27/06/2019As an alternative to power-split hybrid architectures, a simple series-parallel architecture named SPHEV 2 can be realized. In this paper, the sizing process of this architecture is briefly presented and a deeper analysis is made. Mathematical sensitivity analysis studies are conducted on the sizing parameters of the architecture in order to bring more understanding to the optimization results. Local and global sensitivities are performed to understand the influence of the sizing variables on the fuel consumption. An analysis of the sensitivities is also made

Using Nyquist or Nyquist-Like Plot to Predict Three Typical Instabilities in DC-DC Converters

By transforming an exact stability condition, a new Nyquist-like plot is proposed to predict occurrences of three typical instabilities in DC-DC converters. The three instabilities are saddle-node bifurcation (coexistence of multiple solutions), period-doubling bifurcation (subharmonic oscillation), and Neimark bifurcation (quasi-periodic oscillation). In a single plot, it accurately predicts whether an instability occurs and what type the instability is. The plot is equivalent to the Nyquist plot, and it is a useful design tool to avoid these instabilities. Nine examples are used to illustrate the accuracy of this new plot to predict instabilities in the buck or boost converter with fixed or variable switching frequency.Comment: Submitted to an IEEE journal in 201

Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization

Modern antiretroviral therapies have provided HIV-1 infected patients longer lifespans and better quality of life. However, several neurological complications are now being seen in these patients due to HIV-1 associated injury of neurons by infected microglia and astrocytes. In addition, these effects can be further exacerbated with opiate use and abuse. One possible mechanism for such potentiation effects of opiates is the interaction of the mu opioid receptor (MOR) with the chemokine receptor CCR5 (CCR5), a known HIV-1 co-receptor, to form MOR-CCR5 heterodimer. In an attempt to understand this putative interaction and its relevance to neuroAIDS, we designed and synthesized a series of bivalent ligands targeting the putative CCR5-MOR heterodimer. To understand how these bivalent ligands may interact with the heterodimer, biological studies including calcium mobilization inhibition, binding affinity, HIV-1 invasion, and cell fusion assays were applied. In particular, HIV-1 infection assays using human peripheral blood mononuclear cells, macrophages, and astrocytes revealed a notable synergy in activity for one particular bivalent ligand. Further, a molecular model of the putative CCR5-MOR heterodimer was constructed, docked with the bivalent ligand, and molecular dynamics simulations of the complex was performed in a membrane-water system to help understand the biological observation