14 research outputs found
2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa Willd induces apoptosis in human leukemic U937 cells through modulation of MAPK pathways
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CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells
No full textPlant scientists’ research attention is skewed towards colourful, conspicuous and broadly distributed flowers
No full textRelationship between C-Reactive Protein Level and Diabetic Retinopathy: A Systematic Review and Meta-Analysis
No full textTargeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy
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Basement membranes and human disease
No full textIn 1990 the role of basement membranes in human disease was established by the identification of COL4A5 mutations in Alport’s syndrome. Since then the number of diseases caused by mutations in basement membrane components has steadily increased as has our understanding of the roles of basement membranes in organ development and function. However, many questions remain as to the molecular and cellular consequences of these mutations and how they lead to the observed disease phenotypes. Despite this, exciting progress has recently been made with potential treatment options for some of these so far incurable diseases
