Recommendations for Using Real-Time Continuous Glucose Monitoring (rtCGM) Data for Insulin Adjustments in Type 1 Diabetes.

The clinical benefits of real time continuous glucose monitoring (rtCGM) use have been well demonstrated in both CSII- and MDI-treated individuals in large clinical trials. However, recommendations for patient use of rtCGM in everyday life situations are lacking. This article provides guidance to clinicians and patients with type 1 diabetes (T1D) in effective use of rtCGM data, including glucose rate of change (ROC) arrows, for insulin dosing adjustments and other treatment decisions. The recommendations presented here are based on our own clinical experiences as endocrinologists, our personal experiences living with T1D using rtCGM, and findings from a recent survey of T1D patients who have successfully used rtCGM in their self-management. It is important that both clinicians and people with diabetes understand the utility and limitations of rtCGM. Maintaining a collaborative clinician-user relationship remains an important factor in safe, successful rtCGM use

Superdiffusion in the Dissipative Standard Map

We consider transport properties of the chaotic (strange) attractor along unfolded trajectories of the dissipative standard map. It is shown that the diffusion process is normal except of the cases when a control parameter is close to some special values that correspond to the ballistic mode dynamics. Diffusion near the related crisises is anomalous and non-uniform in time: there are large time intervals during which the transport is normal or ballistic, or even superballistic. The anomalous superdiffusion seems to be caused by stickiness of trajectories to a non-chaotic and nowhere dense invariant Cantor set that plays a similar role as cantori in Hamiltonian chaos. We provide a numerical example of such a sticky set. Distribution function on the sticky set almost coincides with the distribution function (SRB measure) of the chaotic attractor.Comment: 10 Figure

Probability of local bifurcation type from a fixed point: A random matrix perspective

Results regarding probable bifurcations from fixed points are presented in the context of general dynamical systems (real, random matrices), time-delay dynamical systems (companion matrices), and a set of mappings known for their properties as universal approximators (neural networks). The eigenvalue spectra is considered both numerically and analytically using previous work of Edelman et. al. Based upon the numerical evidence, various conjectures are presented. The conclusion is that in many circumstances, most bifurcations from fixed points of large dynamical systems will be due to complex eigenvalues. Nevertheless, surprising situations are presented for which the aforementioned conclusion is not general, e.g. real random matrices with Gaussian elements with a large positive mean and finite variance.Comment: 21 pages, 19 figure

Report of conference evaluation committee

A general classification is made of a number of approaches used for the prediction of turbulent shear flows. The sensitivity of these prediction methods to parameter values and initial data are discussed in terms of variable density, pressure fluctuation, gradient diffusion, low Reynolds number, and influence of geometry

Surface waves at a free interface of a saturated porous medium

Surface waves at a free interface of a saturated porous medium are investigated. Existence and peculiarities of surface wave propagation were revealed. Two types of surface waves proved possible: true surface wave, propagating almost without dispersion, and generalized Rayleigh wave, which attenuates along the propagation direction

Simplest miniversal deformations of matrices, matrix pencils, and contragredient matrix pencils

V. I. Arnold [Russian Math. Surveys 26 (2) (1971) 29-43] constructed a simple normal form for a family of complex n-by-n matrices that smoothly depend on parameters with respect to similarity transformations that smoothly depend on the same parameters. We construct analogous normal forms for a family of real matrices and a family of matrix pencils that smoothly depend on parameters, simplifying their normal forms by D. M. Galin [Uspehi Mat. Nauk 27 (1) (1972) 241-242] and by A. Edelman, E. Elmroth, B. Kagstrom [Siam J. Matrix Anal. Appl. 18 (3) (1997) 653-692].Comment: 20 page

On the possibility to supercool molecular hydrogen down to superfluid transition

Recent calculations by Vorobev and Malyshenko (JETP Letters, 71, 39, 2000) show that molecular hydrogen may stay liquid and superfluid in strong electric fields of the order of $4\times 10^7 V/cm$. I demonstrate that strong local electric fields of similar magnitude exist beneath a two-dimensional layer of electrons localized in the image potential above the surface of solid hydrogen. Even stronger local fields exist around charged particles (ions or electrons) if surface or bulk of a solid hydrogen crystal is statically charged. Measurements of the frequency shift of the $1 \to 2$ photoresonance transition in the spectrum of two-dimensional layer of electrons above positively or negatively charged solid hydrogen surface performed in the temperature range 7 - 13.8 K support the prediction of electric field induced surface melting. The range of surface charge density necessary to stabilize the liquid phase of molecular hydrogen at the temperature of superfluid transition is estimated.Comment: 5 pages, 2 figure

Dynamics of the Chain of Oscillators with Long-Range Interaction: From Synchronization to Chaos

We consider a chain of nonlinear oscillators with long-range interaction of the type 1/l^{1+alpha}, where l is a distance between oscillators and 0< alpha <2. In the continues limit the system's dynamics is described by the Ginzburg-Landau equation with complex coefficients. Such a system has a new parameter alpha that is responsible for the complexity of the medium and that strongly influences possible regimes of the dynamics. We study different spatial-temporal patterns of the dynamics depending on alpha and show transitions from synchronization of the motion to broad-spectrum oscillations and to chaos.Comment: 22 pages, 10 figure