215 research outputs found

    Incisional scar evisceration of fallopian tube in a pregnant woman

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    Background: Herniation of pelvic and solid abdominal structures like the fallopian tubes especially in pregnancy is extremely rare. We report a case of an eviscerated fallopian tube through an incisional hernia in a pregnant woman. There has been no such report in literature at the time of report.Case presentation: A case of a 38 year old gravida 3 Para 2 +0, Ibo Nigerian who presented with persistent abdominal pain and protrusion of a fleshy mass from the lower aspect of the anterior abdominal wall of one day duration. She was misdiagnosed as granuloma over the ruptured incisional hernia. At laparotomy, she was found to have a herniating fallopian tube secondary to laevo rotation of the pregnant uterus. This case exhibits one of those rare conditions that could become life threatening and which has a lot of issues to be considered before a decision is made.Conclusion: Evisceration of a fallopian tube through an incisional hernia in a pregnant woman is an uncommon occurrence which is life threatening and prone to misdiagnoses. It is therefore important that a good index of suspicion is created among health personnel especially gynaecologists and general surgeons on the possibility that the fleshy mass on the incisional hernia may be a vital organ like the fallopian tube. This is an original report of impact to the practice of medicin

    Histological study on the staining potentials of Aqueous extract of Ceratonia Siliqua bark

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    This study was designed to determine the staining potentials of aqueous extract of Ceratonia Siliqua bark adapted for the first time as a counter stain in Haematoxylin and Eosin staining reaction. The staining solution was used to stain liver, lung and kidney sections. Phytochemical screening of the extract revealed the presence of tannin (hennatonic acid or Lawsone), while results of the staining reactions showed that Ceratonia siliqua at a low pH, has intense staining qualities, confirming further that the effectiveness of a stain is influenced by the pH of its environment.Key words: Ceratonia siliqua, Extract, Haematoxylin and Eosin, Counterstain, General tissue structure

    The effect of L-arginine on contralateral testes following 7200 Torsion - Detorsion of the Ipsilateral testes.

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    This study was designed to evaluate the effect of torsion-detorsion on ipsilateral testes at 7200 and at time intervals, on the histology of contralateral testes. 20 male rats (130-200g) were involved in the study and allowed to acclimatize for three weeks. They were fed with commercial livestock feeds and tap water ad-libitum, and grouped into seven groups (A-G) of three rats each. In groups A-F, unilateral testicular torsion lasting for 15, 30, and 45 minutes was created. Alternate groups (A, C, and E) were treated intraperitoneally with 150mg/kg/body weight of  Larginine for 1 hour after detorsion, while the remaining groups (B,D,F) were untreated with L-arginine but still allowed to undergo 1 hour detorsion. Group G served as the control. The results showed that group A presented normal seminiferous tubules with intact sertoli cells, and germ cells at various stages of development. The untreated group B presented atrophic seminiferous tubules with loss of germs cells and no luminal spermatozoon, while group D presented normal features except for interstitial hemorrhage. Normal features were observed for groups E (treated) and F (untreated). Thus, L-arginine tends to reduce oxidative stress in the contralateral testes thereby preventing interstitial oedema and preserving the spermatogenic series.Keywords: Torsion-detorsion, Ipsilateral, Contralateral, L-arginine, Ischemia, Reperfusion

    Helicobacter pylori and precancerous conditions of the stomach: The frequency of infection in a cross-sectional study of 79 consecutive patients with chronic antral gastritis in Yaoundé, Cameroon

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    Introduction: The study aimed at determining the different types of precancerous conditions of the stomach and searches the frequency ofHelicobacter pylori in these lesions in patients with chronic antral gastritis in Yaounde, Cameroon.Methods: Five gastric biopsies were performed during upper  gastrointestinal endoscopy for pathology and fixed in formol 10% before being coated in paraffin. Both the modified Giemsa and Periodic acid of Shift – Alkaline blue stains were used for the histological diagnosis of Helicobacter pylori infection. Hematoxylyn and eosin stain was used to determine the activity of gastritis, atrophic gastritis and intestinal  metaplasia in accordance to the Sydney’s classification of gastritis.Data were analysed using both the Epi info 6.04 and Excel 2007 softwares. Means and their standard deviations, medians and their interquartiles(IQR) were calculated. Proportions were established for qualitative variables and chi square analysis done in this study with a p value set at 0.05.Results: Seventy-nine patients with chronic antral gastritis were enrolled, of which 43 (54.4%) were male, median age: 43 years (range from 21 to 70 years). The rate of atrophic gastritis was 74.7% (59/79). The activity of atrophic gastritis was mild in 47.5% (28/59) of cases, moderate in 47.5% (28/59) and severe in 5% (5/59). Intestinal metaplasia and follicular  gastritis were present in 6.3% (5/79), and 10.1% (8/79), respectively.Concerning Helicobacter pylori infection, 71.2% (42/59) of patients with atrophic gastritis tested positive against 28.8% (17/59) who tested negative (p = 0.00003). Helicobacter pylori infection was related to the severity of gastric atrophy (p = 0.0001). Among patients with intestinalmetaplasia and follicular gastritis, the proportion of those who tested positive for Helicobacter pylori infection was 80% (4/5), and 75% (6/8),respectively. There were no significant differences in the occurrence of atrophic gastritis according to age groups (p = 0.908).Conclusion: This study concludes that atrophic gastritis, which is most often caused by Helicobacter pylori, is the most frequent precancerous condition of stomach in Cameroon. Routine gastric sampling for pathologic analysis is mandatory for effective diagnosis and surveillance of Helicobacter pylori infection and precancerous conditions of the stomach

    Participatory planning and quality assessment: contributions of a nursing management technology

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    Objective: to analyze the outcomes of participatory planning and quality assessment of the nursing care provided in a hospital ward using a nursing management technology. Method: Convergent care research focuses on research and practice intervention, developed in a hospital in southern Brazil from April to August 2016. Participatory planning and quality evaluation was performed using the PRAXIS® technology. Results: In the participatory planning, a survey of needs/problems was carried out by 33 professionals followed by 5 workshops, where mission, guiding principles, 4 priority problems, expected results, objectives and plans of activities were defined. For quality evaluation, two indicators were used: satisfaction and notification of adverse events. The evaluation was carried out with 101 patients and /or relatives, predominating “great or good”. Adverse events, 28 records, predominating medication errors. Conclusion: Participatory planning and quality assessment are essential to improve nursing care management and the PRAXIS® technological innovation has been a useful resource.info:eu-repo/semantics/publishedVersio

    The role of polycyclic frameworks in modulating P2X<inf>7</inf> receptor function

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    Herein we describe our recent attempts to target the P2X7 receptor for potential treatment of neurological disorders. This work focusses on different polycycles including carborane, adamantane or cubane, joined by either a cyanoguanidine or an amide linker to phenyl or isoquinoline moieties. We have demonstrated the superiority of the adamantyl moiety over other polycycles in terms of synthetic accessibility and biological (cellular) activity. We have also shown that an amide or cyanoguanidine linker can greatly alter the biological activity of compounds. This SAR study provides important insights into the types of functionality required to target the P2X7 receptor

    Low Temperature Ignition of Biomass

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    Biomass is an especially reactive fuel. There have been large increases in the transportation and utilisation of biomass fuels over the past 10 years and this has raised concerns over its safe handling and utilisation. Fires, and sometimes explosions, are a risk during all stages of fuel production as well as during the handling and utilisation of the product. This paper presents a method for assessing ignition risk and provides a ranking of relative risk of ignition of biomass fuels. Tests involved single particle measurements, thermal analysis, dust layer and basket ignition tests. In all cases, smouldering combustion was observed, whereby the fuels pyrolyse to produce a black char, which then subsequently ignites. Low temperature pyrolysis kinetics have been utilised to predict ignition delay times at low temperatures. A method for evaluating risk was explored based on the activation energy for pyrolysis and a characteristic temperature from TGA analysis. Here, olive cake, sunflower husk and Miscanthus fall into the high risk category, while the woods, plane, pine, mesquite and red berry juniper, fall into the medium risk category. This method is able to capture the impact of low activation energy for pyrolysis on the increased risk of ignition

    The role of bioenergy and biochemicals in CO2 mitigation through the energy system - a scenario analysis for the Netherlands

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    Bioenergy as well as bioenergy with carbon capture and storage are key options to embark on cost-efficient trajectories that realize climate targets. Most studies have not yet assessed the influence on these trajectories of emerging bioeconomy sectors such as biochemicals and renewable jet fuels (RJFs). To support a systems transition, there is also need to demonstrate the impact on the energy system of technology development, biomass and fossil fuel prices. We aim to close this gap by assessing least-cost pathways to 2030 for a number of scenarios applied to the energy system of the Netherlands, using a cost-minimization model. The type and magnitude of biomass deployment are highly influenced by technology development, fossil fuel prices and ambitions to mitigate climate change. Across all scenarios, biomass consumption ranges between 180 and 760 PJ and national emissions between 82 and 178 Mt CO2. High technology development leads to additional 100-270 PJ of biomass consumption and 8-20 Mt CO2 emission reduction compared to low technology development counterparts. In high technology development scenarios, additional emission reduction is primarily achieved by bioenergy and carbon capture and storage. Traditional sectors, namely industrial biomass heat and biofuels, supply 61-87% of bioenergy, while wind turbines are the main supplier of renewable electricity. Low technology pathways show lower biochemical output by 50-75%, do not supply RJFs and do not utilize additional biomass compared to high technology development. In most scenarios the emission reduction targets for the Netherlands are not met, as additional reduction of 10-45 Mt CO2 is needed. Stronger climate policy is required, especially in view of fluctuating fossil fuel prices, which are shown to be a key determinant of bioeconomy development. Nonetheless, high technology development is a no-regrets option to realize deep emission reduction as it also ensures stable growth for the bioeconomy even under unfavourable conditions.</p

    Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome

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    <p>Abstract</p> <p>Background</p> <p>Differential diagnosis between acute cardiogenic pulmonary edema (APE) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS) may often be difficult. We evaluated the ability of chest sonography in the identification of characteristic pleuropulmonary signs useful in the diagnosis of ALI/ARDS and APE.</p> <p>Methods</p> <p>Chest sonography was performed on admission to the intensive care unit in 58 consecutive patients affected by ALI/ARDS or by acute pulmonary edema (APE).</p> <p>Results</p> <p>Ultrasound examination was focalised on finding in the two groups the presence of: 1) alveolar-interstitial syndrome (AIS) 2) pleural lines abnormalities 3) absence or reduction of "gliding" sign 4) "spared areas" 5) consolidations 6) pleural effusion 7) "lung pulse".</p> <p>AIS was found in 100% of patients with ALI/ARDS and in 100% of patients with APE (p = ns). Pleural line abnormalities were observed in 100% of patients with ALI/ARDS and in 25% of patients with APE (p < 0.0001). Absence or reduction of the 'gliding sign' was observed in 100% of patients with ALI/ARDS and in 0% of patients with APE. 'Spared areas' were observed in 100% of patients with ALI/ARDS and in 0% of patients with APE (p < 0.0001). Consolidations were present in 83.3% of patients with ALI/ARDS in 0% of patients with APE (p < 0.0001). A pleural effusion was present in 66.6% of patients with ALI/ARDS and in 95% of patients with APE (p < 0.004). 'Lung pulse' was observed in 50% of patients with ALI/ARDS and in 0% of patients with APE (p < 0.0001).</p> <p>All signs, except the presence of AIS, presented a statistically significant difference in presentation between the two syndromes resulting specific for the ultrasonographic characterization of ALI/ARDS.</p> <p>Conclusion</p> <p>Pleuroparenchimal patterns in ALI/ARDS do find a characterization through ultrasonographic lung scan. In the critically ill the ultrasound demonstration of a dyshomogeneous AIS with spared areas, pleural line modifications and lung consolidations is strongly predictive, in an early phase, of non-cardiogenic pulmonary edema.</p
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