Preparation and Medico-Biological Tests Nanocolloids Radiopharmaceuticals on the Based of Modified DTPA Labeled Technetium-99m

Technetium-99m recovery process in the presence of stannous Sn (II) with the aim to determine it is necessary and sufficient quantity, that would provide a complete "recovery" of 99mTc in the reaction mixture has been investigated. The studies were identified conditions for receiving radioactive nanopreparations based on a modified molecule DTPA. The authors has been shown that the direct interaction of 99mTc eluate solution with a solution of a mixture of SnCl2 DTPAmod and radiochemical impurity content unreduced 99mTc (VII) in the preparation labeled with nanocolloids is 2,7% and the yield nanocolloids with the size of 100 nm is about 80%. The medical-biological testing of the agents 99mTc (IV) - DTPAmod on test animals for the determination of the functional suitability for the scintigraphic imaging of lymph nodes has been carried out. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3540

Accounting and Analysis in Managing the Cost Of Innovation

The article reveals the theoretical and practical aspects of accounting and analysis in managing the cost of innovation. Innovation process is a process of successive transformation of ideas into goods including stages of basic and applied research, engineering development, marketing, production and distribution. The purpose of accounting and analysis in managing the cost of innovation is to find a solution that would best meet the needs of all participants in the innovation process, and provide the required level of profitability of the project costs. DOI: 10.5901/mjss.2015.v6n1s3p21

Development methods labeled technetium-99m magnetically nanocolloids for medical diagnosis

The opportunity of drawing of a radioactive label 99mTc on a surface nanoparticles of iron Fe2C, covered by a carbon environment, and also particles Fe2C (IDA), modified arenediazoniumtosylates is investigated. It is shown, that on not modified particles about 11,2 % 99mɌɫ from its entered quantity are adsorbed. Thus the size of atomic adsorption does not exceed 0,736·10-9 g-ɚt/g 99mɌɫ on 1 g Fe2C. On the modified particles Fe@C (IDA) physical adsorption is not observed. At their chemical interaction with 99mTc at presence of reducing agent of tin (II) output labeled a product increases more than in 1,5 times and makes 21,3 % from the general entered activity radionuclide. For achievement of higher output carrying out of the researches connected with selection of optimum concentration and conditions of preparation of a reducer or selection of other more effective reducer is necessary. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2065

Nonperturbative late time asymptotics for heat kernel in gravity theory

Recently proposed nonlocal and nonperturbative late time behavior of the heat kernel is generalized to curved spacetimes. Heat kernel trace asymptotics is dominated by two terms one of which represents a trivial covariantization of the flat-space result and another one is given by the Gibbons-Hawking integral over asymptotically-flat infinity. Nonlocal terms of the effective action generated by this asymptotics might underly long- distance modifications of the Einstein theory motivated by the cosmological constant problem. New mechanisms of the cosmological constant induced by infrared effects of matter and graviton loops are briefly discussed.Comment: 22 pages, LaTeX, final version, to be published in Phys. Rev.

Elliptic flow of charged particles at midrapidity relative to the spectator plane in Pb–Pb and Xe–Xe collisions

Measurements of the elliptic flow coefficient relative to the collision plane defined by the spectator neutrons v2{ SP} in collisions of Pb ions at center-of-mass energy per nucleon–nucleon pair √ 2.76 TeV and Xe ions at √ sNN = sNN =5.44 TeV are reported. The results are presented for charged particles produced at midrapidity as a function of centrality and transverse momentum for the 5–70% and 0.2–6 GeV/c ranges, respectively. The ratio between v2{ SP} and the elliptic flow coefficient relative to the participant plane v2{4}, estimated using four-particle correlations, deviates by up to 20% from unity depending on centrality. This observation differs strongly from the magnitude of the corresponding eccentricity ratios predicted by the TRENTo and the elliptic power models of initial state fluctuations that are tuned to describe the participant plane anisotropies. The differences can be interpreted as a decorrelation of the neutron spectator plane and the reaction plane because of fragmentation of the remnants from the colliding nuclei, which points to an incompleteness of current models describing the initial state fluctuations. A significant transverse momentum dependence of the ratio v2{ SP}/v2{4} is observed in all but the most central collisions, which may help to understand whether momentum anisotropies at low and intermediate transverse momentum have a common origin in initial state f luctuations. The ratios of v2{ SP} and v2{4} to the corresponding initial state eccentricities for Xe–Xe and Pb–Pb collisions at similar initial entropy density show a difference of (7.0 ±0.9)%with an additional variation of +1.8% when including RHIC data in the TRENTo parameter extraction. These observations provide new experimental constraints for viscous effects in the hydrodynamic modeling of the expanding quark–gluon plasma produced in heavy-ion collisions at the LHC

First measurement of Ωc0 production in pp collisions at s=13 TeV

The inclusive production of the charm–strange baryon 0 c is measured for the first time via its hadronic √ decay into −π+ at midrapidity (|y| <0.5) in proton–proton (pp) collisions at the centre-of-mass energy s =13 TeV with the ALICE detector at the LHC. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 2 < pT < 12 GeV/c. The pT dependence of the 0 c-baryon production relative to the prompt D0-meson and to the prompt 0 c-baryon production is compared to various models that take different hadronisation mechanisms into consideration. In the measured pT interval, the ratio of the pT-integrated cross sections of 0 c and prompt + c baryons multiplied by the −π+ branching ratio is found to be larger by a factor of about 20 with a significance of about 4σ when compared to e+e− collisions

Hydrodynamics and sediment transport modelling in estuarine environment with slon model

Proceedings of the Coastal Engineering Conference2316-2328PCEC

High-Cluster (Cu9) Cage Silsesquioxanes: Synthesis, Structure, and Catalytic Activity

Unusual high-cluster (Cu9) cage phenylsilsesquioxanes were obtained via complexation of in situ CuII,Na-silsesquioxane species formed with phenanthroline and neocuproine. In the first case, phenanthroline, acting as "a silent ligand" (not participating in the composition of the final product), favors the formation of an unprecedented cagelike phenylsilsesquioxane of Cu9Na6 nuclearity, 1. In the second case, neocuproine ligands withdraws two Cu ions from the metallasilsesquioxane matrix, producing two cationic fragments Cu+(neocuproine)2. The remaining metallasilsesquioxane is rearranged into an anionic cage of Cu9Na4 nuclearity, finalizing the formation of a specific ionic complex, 2. The impressive molecular architecture of both types of complexes, e.g., the presence of different (cyclic/acyclic) types of silsesquioxane ligands, was established by single-crystal X-ray diffraction studies. Compound 1 was revealed to be highly active in the oxidative amidation of benzylic alcohol and the catalyst loading could be reduced down to 100 ppm of Cu. Catalytic studies of compound 1 demonstrated its high activity in hydroperoxidation of alkanes with H2O2 and oxidation of alcohols to ketones with tert-BuOOH. © 2018 American Chemical Society

High-Cluster (Cu9) Cage Silsesquioxanes: Synthesis, Structure, and Catalytic Activity

Unusual high-cluster (Cu9) cage phenylsilsesquioxanes were obtained via complexation of in situ CuII,Na-silsesquioxane species formed with phenanthroline and neocuproine. In the first case, phenanthroline, acting as "a silent ligand" (not participating in the composition of the final product), favors the formation of an unprecedented cagelike phenylsilsesquioxane of Cu9Na6 nuclearity, 1. In the second case, neocuproine ligands withdraws two Cu ions from the metallasilsesquioxane matrix, producing two cationic fragments Cu+(neocuproine)2. The remaining metallasilsesquioxane is rearranged into an anionic cage of Cu9Na4 nuclearity, finalizing the formation of a specific ionic complex, 2. The impressive molecular architecture of both types of complexes, e.g., the presence of different (cyclic/acyclic) types of silsesquioxane ligands, was established by single-crystal X-ray diffraction studies. Compound 1 was revealed to be highly active in the oxidative amidation of benzylic alcohol and the catalyst loading could be reduced down to 100 ppm of Cu. Catalytic studies of compound 1 demonstrated its high activity in hydroperoxidation of alkanes with H2O2 and oxidation of alcohols to ketones with tert-BuOOH. © 2018 American Chemical Society

A mid-Holocene geochemical record of saline inflow to the Gotland Deep, Baltic Sea

The formation of Mn-enrichments in Gotland Deep sediments has been linked to the occurrence of periodic inflows of saline water from the North Sea. In turn these saline inflow events are very strongly linked to variation in North Atlantic atmospheric conditions. Here sedimentary Mn-concentrations in mid-Holocene sediments are measured with a 0.5 mm sampling resolution using scanning electron microscope techniques. As the sedimentation rate in core 20001-5 was estimated to be approximately 0.5–1 mm per year, examining the variation in Mn-enrichments may potentially provide an annual record of variation in saline inflow, and by extension, North Atlantic climate on interannual timescales. There are many processes that can affect Mn-cycling in the Gotland Deep. When considered together, these processes could potentially act to remove or significantly weaken the transmission of the primary saline inflow signal to the measured geochemical record, producing an effectively random Mn-record. Analysis of the Mn-record as a time series of discrete events revealed that the Mn-record was not consistent with a random distribution of events, and contains some long-term order. Spectral analysis of the Mn-record then indicates a significant periodicity in the Mn-record between 33 and 35.5 mm. This represents a discrete decadal periodicity in Mn-enrichment at 25–55 years that is consistent with the timing of previously reported Mn-enrichments in Gotland Deep sediments