Volkov-Akulov theory and D-branes

The action of supersymmetric Born-Infeld theory (D-9-brane in a Lorentz covariant static gauge) has a geometric form of the Volkov-Akulov-type. The first non-linearly realized supersymmetry can be made manifest, the second world-volume supersymmetry is not manifest. We also study the analogous 2 supersymmetries of the quadratic action of the covariantly quantized D-0-brane. We show that the Hamiltonian and the BRST operator are build from these two supersymmetry generators.Comment: 10 pages, Latex, Contribution to Supersymmetry and Quantum Field Theory, International Seminar dedicated to the memory of D. V. Volkov (Kharkov, 1997

The geometrical form for the string space-time action

In the present article, we derive the space-time action of the bosonic string in terms of geometrical quantities. First, we study the space-time geometry felt by probe bosonic string moving in antisymmetric and dilaton background fields. We show that the presence of the antisymmetric field leads to the space-time torsion, and the presence of the dilaton field leads to the space-time nonmetricity. Using these results we obtain the integration measure for space-time with stringy nonmetricity, requiring its preservation under parallel transport. We derive the Lagrangian depending on stringy curvature, torsion and nonmetricity.Comment: 13 page

Comment about UV regularization of basic commutators in string theories

Recently proposed by Hwang, Marnelius and Saltsidis zeta regularization of basic commutators in string theories is generalized to the string models with non-trivial vacuums. It is shown that implementation of this regularization implies the cancellation of dangerous terms in the commutators between Virasoro generators, which break Jacobi identity.Comment: LaTeX, 9 pages, no figures, submitted to Physics Letters

The Green--Schwarz Superstring in Extended Configuration Space and Infinitely Reducible First Class Constraints Problem

The Green--Schwarz superstring action is modified to include some set of additional (on-shell trivial) variables. A complete constraints system of the theory turns out to be reducible both in the original and in additional variable sectors. The initial $8s$ first class constraints and $8c$ second class ones are shown to be unified with $8c$ first and $8s$ second class constraints from the additional variables sector, resulting with $SO(1,9)$-covariant and linearly independent constraint sets. Residual reducibility proves to fall on second class constraints only.Comment: 14 pages, LaTe

Study of neutron response and n-gamma discrimination by charge comparison method for small liquid scintillation detector

The study of the neutron response and n-gamma discrimination for small (18x26x8) mm3 liquid scintillator BC501A (Bicron) detector was carried out by digital charge comparison method. Three ranges of neutron energies were used: uniform distribution from 0.95 MeV to 1.23 MeV, continuous spectra of AmBe source and monoenergetic 16.2 MeV neutrons. The obtained results are compared with those for cylindrical liquid scintillation detector (40 mm diameter, 60 mm length) at the same energies of neutrons. A dramatic fall of the neutron response function at 400 keVee for small detector at 16.2 MeV neutron energy was measured. For (0.95 - 1.23) MeV neutron energy range such fall takes place at 260 keVee. The greater slope of neutron locus at (0.95 - 1.23) MeV neutron energy comparing to 16.2 MeV for both detectors is explained by longer tail of pulse from proton recoils within (0.1-1.23) MeV energy range.Comment: submitted to Nuclear Instruments and Methods in Phys. Res. Sect.

4-point effective actions in open and closed superstring theory

Recently the effective action for the 4-point functions in abelian open superstring theory has been derived, giving an explicit construction of the bosonic and fermionic terms of this infinite $\alpha'$ series. In the present work we generalize this result to the nonabelian case. We test our result, at ${\alpha'}^3$ and ${\alpha'}^4$ order, with several existing versions for these terms, finding agreement in most of the cases. We also apply these ideas to derive the effective action for the 4-point functions of the NS-NS sector of closed superstring theory, to all order in $\alpha'$.Comment: 26 pages, 1 figure. To appear in JHE

Endocrine disruptor compounds-a cause of impaired immune tolerance driving inflammatory disorders of pregnancy?

Endocrine disrupting compounds (EDCs) are prevalent and ubiquitous in our environment and have substantial potential to compromise human and animal health. Amongst the chronic health conditions associated with EDC exposure, dysregulation of reproductive function in both females and males is prominent. Human epidemiological studies demonstrate links between EDC exposure and infertility, as well as gestational disorders including miscarriage, fetal growth restriction, preeclampsia, and preterm birth. Animal experiments show EDCs administered during gestation, or to either parent prior to conception, can interfere with gamete quality, embryo implantation, and placental and fetal development, with consequences for offspring viability and health. It has been presumed that EDCs operate principally through disrupting hormone-regulated events in reproduction and fetal development, but EDC effects on maternal immune receptivity to pregnancy are also implicated. EDCs can modulate both the innate and adaptive arms of the immune system, to alter inflammatory responses, and interfere with generation of regulatory T (Treg) cells that are critical for pregnancy tolerance. Effects of EDCs on immune cells are complex and likely exerted by both steroid hormone-dependent and hormone-independent pathways. Thus, to better understand how EDCs impact reproduction and pregnancy, it is imperative to consider how immune-mediated mechanisms are affected by EDCs. This review will describe evidence that several EDCs modify elements of the immune response relevant to pregnancy, and will discuss the potential for EDCs to disrupt immune tolerance required for robust placentation and optimal fetal development.John E. Schjenken, Ella S. Green, Tenuis S. Overduin, Chui Yan Mah, Darryl L. Russell and Sarah A. Robertso

Four dimensional "old minimal" N=2 supersymmetrization of R^4

We write in superspace the lagrangian containing the fourth power of the Weyl tensor in the "old minimal" d=4, N=2 supergravity, without local SO(2) symmetry. Using gauge completion, we analyze the lagrangian in components. We find out that the auxiliary fields which belong to the Weyl and compensating vector multiplets have derivative terms and therefore cannot be eliminated on-shell. Only the auxiliary fields which belong to the compensating nonlinear multiplet do not get derivatives and could still be eliminated; we check that this is possible in the leading terms of the lagrangian. We compare this result to the similar one of "old minimal" N=1 supergravity and we comment on possible generalizations to other versions of N=1,2 supergravity.Comment: 31 pages, no figures. Minor corrections. Details of the full calculation included as an appendix. Reference adde

String Theory, Unification and Quantum Gravity

An overview is given of the way in which the unification program of particle physics has evolved into the proposal of superstring theory as a prime candidate for unifying quantum gravity with the other forces and particles of nature. A key concern with quantum gravity has been the problem of ultraviolet divergences, which is naturally solved in string theory by replacing particles with spatially extended states as the fundamental excitations. String theory turns out, however, to contain many more extended-object states than just strings. Combining all this into an integrated picture, called M-theory, requires recognition of the r\^ole played by a web of nonperturbative duality symmetries suggested by the nonlinear structures of the field-theoretic supergravity limits of string theory.Comment: 29 pages, 13 figures, 3 tables; Lectures given at the 6th Aegean Summer School "Quantum Gravity and Quantum Cosmology", Chora, Naxos Island, Greece, 12-17 September 201

Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

Seminal fluid factors modulate the female immune response at conception to facilitate embryo implantation and reproductive success. Whether sperm affect this response has not been clear. We evaluated global gene expression by microarray in the mouse uterus after mating with intact or vasectomized males. Intact males induced greater changes in gene transcription, prominently affecting pro-inflammatory cytokine and immune regulatory genes, with TLR4 signaling identified as a top-ranked upstream driver. Recruitment of neutrophils and expansion of peripheral regulatory T cells were elevated by seminal fluid of intact males. In vitro, epididymal sperm induced IL6, CXCL2, and CSF3 in uterine epithelial cells of wild-type, but not Tlr4 null females. Collectively these experiments show that sperm assist in promoting female immune tolerance by eliciting uterine cytokine expression through TLR4-dependent signaling. The findings indicate a biological role for sperm beyond oocyte fertilization, in modulating immune mechanisms involved in female control of reproductive investment.John E. Schjenken, David J. Sharkey, Ella S. Green, Hon Yeung Chan, Ricky A. Matias, Lachlan M. Moldenhauer and Sarah A. Robertso