6 research outputs found
Einfluss der Lichtfaktoren auf die KohlensSureassimilation der Laub. ' blatter.
No full textAus : Dansk botanisk Arkiv. Bd.IO, Heft 1.LEIDSSTELSELCHECK1875-1899ONAANGEROERDOPLADEN-RUG0
Phototsynthetic efficiency of Betula pendula acclimated to different quantum flux densities.
No full textA systematic relationship between phytochrome-controlled development and species habitat, for plants grown in simulated natural radiation
No full textIs plasticity in partitioning of photosynthetic resources between and within leaves important for whole-plant carbon gain in canopies?
No full text
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
No full textOsteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 osteoarthritis phenotypes, 52 of which have not been associated with the disease before. We report thumb and spine osteoarthritis risk variants and identify differences in genetic effects between weight-bearing and non-weight-bearing joints. We identify sex-specific and early age-at-onset osteoarthritis risk loci. We integrate functional genomics data from primary patient tissues (including articular cartilage, subchondral bone, and osteophytic cartilage) and identify high-confidence effector genes. We provide evidence for genetic correlation with phenotypes related to pain, the main disease symptom, and identify likely causal genes linked to neuronal processes. Our results provide insights into key molecular players in disease processes and highlight attractive drug targets to accelerate translation. © 2021 The Author
