Fourteen Years of Education and Public Outreach for the Swift Gamma-ray Burst Explorer Mission

The Sonoma State University (SSU) Education and Public Outreach (E/PO) group leads the Swift Education and Public Outreach program. For Swift, we have previously implemented broad efforts that have contributed to NASA's Science Mission Directorate E/PO portfolio across many outcome areas. Our current focus is on highly-leveraged and demonstrably successful activities, including the wide-reaching Astrophysics Educator Ambassador program, and our popular websites: Epo's Chronicles and the Gamma-ray Burst (GRB) Skymap. We also make major contributions working collaboratively through the Astrophysics Science Education and Public Outreach Forum (SEPOF) on activities such as the on-line educator professional development course NASA's Multiwavelength Universe. Past activities have included the development of many successful education units including the GEMS Invisible Universe guide, the Gamma-ray Burst Educator's guide, and the Newton's Laws Poster set; informal activities including support for the International Year of Astronomy, the development of a toolkit about supernovae for the amateur astronomers in the Night Sky Network, and the Swift paper instrument and glider models.Comment: 7th Huntsville Gamma-Ray Burst Symposium, GRB 2013: paper 42 in eConf Proceedings C130414

Electro-Optic Modulation of Single Photons

We use the Stokes photon of a biphoton pair to set the time origin for electro-optic modulation of the wave function of the anti-Stokes photon thereby allowing arbitrary phase and amplitude modulation. We demonstrate conditional single-photon wave functions composed of several pulses, or instead, having gaussian or exponential shapes

Lessons from Non-Abelian Plasma Instabilities in Two Spatial Dimensions

Plasma instabilities can play a fundamental role in quark-gluon plasma equilibration in the high energy (weak coupling) limit. Early simulations of the evolution of plasma instabilities in non-abelian gauge theory, performed in one spatial dimension, found behavior qualitatively similar to traditional QED plasmas. Later simulations of the fully three-dimensional theory found different behavior, unlike traditional QED plasmas. To shed light on the origin of this difference, we study the intermediate case of two spatial dimensions. Depending on how the "two-dimensional'' theory is formulated, we can obtain either behavior.Comment: 15 pages, 10 figure

Sonic hedgehog medulloblastoma cancer stem cells mirnome and transcriptome highlight novel functional networks

Molecular classification has improved the knowledge of medulloblastoma (MB), the most common malignant brain tumour in children, however current treatments cause severe side effects in patients. Cancer stem cells (CSCs) have been described in MB and represent a sub population characterised by self-renewal and the ability to generate tumour cells, thus representing the reservoir of the tumour. To investigate molecular pathways that characterise this sub population, we isolated CSCs from Sonic Hedgehog Medulloblastoma (SHH MB) arisen in Patched 1 (Ptch1) heterozygous mice, and performed miRNA-and mRNA-sequencing. Comparison of the miRNA-sequencing of SHH MB CSCs with that obtained from cerebellar Neural Stem Cells (NSCs), allowed us to obtain a SHH MB CSC miRNA differential signature. Pathway enrichment analysis in SHH MB CSCs mirnome and transcriptome was performed and revealed a series of enriched pathways. We focused on the putative targets of the SHH MB CSC miRNAs that were involved in the enriched pathways of interest, namely pathways in cancer, PI3k-Akt pathway and protein processing in endoplasmic reticulum pathway. In silico analysis was performed in SHH MB patients and identified several genes, whose expression was associated with worse overall survival of SHH MB patients. This study provides novel candidates whose functional role should be further investigated in SHH MB