9,616 research outputs found
Multiphase modelling of vascular tumour growth in two spatial dimensions
In this paper we present a continuum mathematical model of vascular tumour growth which is based on a multiphase framework in which the tissue is decomposed into four distinct phases and the principles of conservation of mass and momentum are applied to the normal/healthy cells, tumour cells, blood vessels and extracellular material. The inclusion of a diffusible nutrient, supplied by the blood vessels, allows the vasculature to have a nonlocal influence on the other phases. Two-dimensional computational simulations are carried out on unstructured, triangular meshes to allow a natural treatment of irregular geometries, and the tumour boundary is captured as a diffuse interface on this mesh, thereby obviating the need to explicitly track the (potentially highly irregular and ill-defined) tumour boundary. A hybrid finite volume/finite element algorithm is used to discretise the continuum model: the application of a conservative, upwind, finite volume scheme to the hyperbolic mass balance equations and a finite element scheme with a stable element pair to the generalised Stokes equations derived from momentum balance, leads to a robust algorithm which does not use any form of artificial stabilisation. The use of a matrix-free Newton iteration with a finite element scheme for the nutrient reaction-diffusion equations allows full nonlinearity in the source terms of the mathematical model. Numerical simulations reveal that this four-phase model reproduces the characteristic pattern of tumour growth in which a necrotic core forms behind an expanding rim of well-vascularised proliferating tumour cells. The simulations consistently predict linear tumour growth rates. The dependence of both the speed with which the tumour grows and the irregularity of the invading tumour front on the model parameters are investigated
Cumulant expansion of the periodic Anderson model in infinite dimension
The diagrammatic cumulant expansion for the periodic Anderson model with
infinite Coulomb repulsion () is considered here for an hypercubic
lattice of infinite dimension (). The same type of simplifications
obtained by Metzner for the cumulant expansion of the Hubbard model in the
limit of , are shown to be also valid for the periodic Anderson
model.Comment: 13 pages, 7 figures.ps. To be published in J. Phys. A: Mathematical
and General (1997
Effect of Particle-Hole Asymmetry on the Mott-Hubbard Metal-Insulator Transition
The Mott-Hubbard metal-insulator transition is one of the most important
problems in correlated electron systems. In the past decade, much progress has
been made on examining a particle-hole symmetric form of the transition in the
Hubbard model with dynamical mean field theory where it was found that the
electronic self energy develops a pole at the transition. We examine the
particle-hole asymmetric metal-insulator transition in the Falicov-Kimball
model, and find that a number of features change when the noninteracting
density of states has a finite bandwidth. Since, generically particle-hole
symmetry is broken in real materials, our results have an impact on
understanding the metal-insulator transition in real materials.Comment: 5 pages, 3 figure
Compressibility of the Two-Dimensional infinite-U Hubbard Model
We study the interactions between the coherent quasiparticles and the
incoherent Mott-Hubbard excitations and their effects on the low energy
properties in the Hubbard model. Within the framework of a
systematic large-N expansion, these effects first occur in the next to leading
order in 1/N. We calculate the scattering phase shift and the free energy, and
determine the quasiparticle weight Z, mass renormalization, and the
compressibility. It is found that the compressibility is strongly renormalized
and diverges at a critical doping . We discuss the nature
of this zero-temperature phase transition and its connection to phase
separation and superconductivity.Comment: 4 pages, 3 eps figures, final version to appear in Phys. Rev. Let
Fractional Aharonov-Bohm effect in mesoscopic rings
We study the effects of correlations on a one dimensional ring threaded by a
uniform magnetic flux. In order to describe the interaction between particles,
we work in the framework of the U Hubbard and - models. We focus
on the dilute limit. Our results suggest the posibility that the persistent
current has an anomalous periodicity , where is an integer in
the range ( is the number of particles in the ring
and is the flux quantum). We found that this result depends neither
on disorder nor on the detailed form of the interaction, while remains the on
site infinite repulsion.Comment: 14 pages (Revtex), 5 postscript figures. Send e-mail to:
[email protected]
Wigner crystallization in Na(3)Cu(2)O(4) and Na(8)Cu(5)O(10) chain compounds
We report the synthesis of novel edge-sharing chain systems Na(3)Cu(2)O(4)
and Na(8)Cu(5)O(10), which form insulating states with commensurate charge
order. We identify these systems as one-dimensional Wigner lattices, where the
charge order is determined by long-range Coulomb interaction and the number of
holes in the d-shell of Cu. Our interpretation is supported by X-ray structure
data as well as by an analysis of magnetic susceptibility and specific heat
data. Remarkably, due to large second neighbor Cu-Cu hopping, these systems
allow for a distinction between the (classical) Wigner lattice and the 4k_F
charge-density wave of quantum mechanical origin.Comment: 4 pages, 4 figure
Variational cluster approach to correlated electron systems in low dimensions
A self-energy-functional approach is applied to construct cluster
approximations for correlated lattice models. It turns out that the
cluster-perturbation theory (Senechal et al, PRL 84, 522 (2000)) and the
cellular dynamical mean-field theory (Kotliar et al, PRL 87, 186401 (2001)) are
limiting cases of a more general cluster method. Results for the
one-dimensional Hubbard model are discussed with regard to boundary conditions,
bath degrees of freedom and cluster size.Comment: 4 pages, final version with minor change
Cluster coherent potential approximation for electronic structure of disordered alloys
We extend the single-site coherent potential approximation (CPA) to include
the effects of non-local disorder correlations (alloy short-range order) on the
electronic structure of random alloy systems. This is achieved by mapping the
original Anderson disorder problem to that of a selfconsistently embedded
cluster. This cluster problem is then solved using the equations of motion
technique. The CPA is recovered for cluster size , and the disorder
averaged density-of-states (DOS) is always positive definite. Various new
features, compared to those observed in CPA, and related to repeated scattering
on pairs of sites, reflecting the effect of SRO are clearly visible in the DOS.
It is explicitly shown that the cluster-CPA method always yields
positive-definite DOS. Anderson localization effects have been investigated
within this approach. In general, we find that Anderson localization sets in
before band splitting occurs, and that increasing partial order drives a
continuous transition from an Anderson insulator to an incoherent metal.Comment: 7 pages, 6 figures. submitted to PR
Portfolio Diversification With NAFTA Equities
The results of our analysis suggests that diversified investment in the Mexican stock market has provided significant diversification and returns enhancement benefits to U. S. investors and that Canadian stocks offer only occasional return/risk improvement over a U.S. equities portfolio. When correlations among the three markets are considered, we see diversification opportunities in the longer periods of returns but also increasing convergence of the Mexican and Canadian markets with the U.S. stock market in recent years. The implications of our findings are that, if 17 years of returns data are representative of future expectations, there are clear return/risk enhancing advantages to including Mexican stocks in U.S. portfolio
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